Clinical trials
Rejection clinical trials
Below are recruiting rejection clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06774365Recruiting
Heart imaging and blood tests for transplant rejection detection
This study uses advanced heart imaging and blood tests to detect a type of rejection that can happen after a heart transplant. It may help doctors diagnose antibody-mediated rejection earlier and more accurately.
Bari, BariAges 18 years+ - NCT04615221Recruiting
Study of immune rejection after uterine transplant
This study looks at why the body’s immune system may reject a transplanted uterus or a related surgery. Your results may help doctors understand rejection and improve care for future uterine transplants.
SuresnesAges 18–45 - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT07081126Recruiting
Daratumumab for late antibody-mediated rejection in kidney transplant
This trial tests whether daratumumab can help treat a type of rejection that happens more than a year after a kidney transplant. It may be an option for people who have biopsy-proven antibody-mediated rejection and new donor-specific antibodies.
MartinAges 18 years+ - NCT07673536Recruiting
Heart transplant monitoring with extracellular vesicles
This study uses tiny particles called extracellular vesicles (which cells release) to check for signs of organ rejection after a heart transplant, aiming for a safer and less invasive alternative to biopsies.
Berlin, State of BerlinAges 18 years+ - NCT06112951Recruiting
ECP treatment for early signs of lung transplant rejection
This trial tests whether a therapy called extracorporeal photopheresis (ECP) can stop early, silent rejection in lung transplant patients. It is for people who have developed donor-specific antibodies but still have normal lung function.
ViennaAges 18 years+ - NCT06100965Recruiting
Lower dose alemtuzumab for kidney transplant rejection
This trial tests a reduced dose of alemtuzumab, a medicine that calms the immune system, for people whose kidney transplant is being rejected and standard treatments haven't worked or aren't safe.
Rotterdam, South HollandAges 18 years+ - NCT05375149Recruiting
Breath particle study after lung transplant
This study looks at tiny particles in exhaled breath after a lung transplant. It may help researchers understand how the lungs are doing after transplant by using breath samples.
Lund, Skåne CountyAges 16–75 - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT07053488RecruitingPhase 1/Phase 2
Gene-edited liver transplant to lower rejection risk
This trial tests a liver transplant using a donor organ that has been gene-edited to reduce the risk of rejection. It may help people who need a liver transplant and are not a perfect tissue match with their donor.
Beijing, ChangpingAges 16–85 - NCT06939751Recruiting
Testing microRNA levels to personalize heart transplant care
This trial is studying whether a blood test that measures small molecules called microRNAs can help doctors personalize the medicines used to prevent rejection after a heart transplant. If you qualify, you would help researchers learn how to better match immunosuppression to each patient's needs.
Los Angeles, CaliforniaAges 18–99 - NCT06532890Recruiting
Using microRNAs to personalize heart transplant medicines in children
This study is looking at heart transplant children (up to age 18) to see if measuring tiny molecules called microRNAs in the blood can help doctors personalize anti-rejection medicines. It aims to improve how we prevent rejection while reducing side effects.
Aurora, ColoradoAges Up to 18 years - NCT07060716Recruiting
Blood test to monitor kidney transplant health
This study is testing a blood test that looks for tiny pieces of the donor's DNA in your blood to check how your new kidney is doing. It may help doctors monitor your transplant and spot problems early, possibly without needing a biopsy.
Los Angeles, CaliforniaAges 18 years+ - NCT06982404Recruiting
Heart transplant biopsy study
This study tests whether a small biopsy taken from a donor heart before transplant can predict how well the heart will work after surgery. The goal is to improve transplant success for recipients.
Vienna, State of ViennaAges Any age - NCT06910527Recruiting
Testing blood and urine for kidney rejection signs
This study is for people with a kidney transplant who are in the hospital for a biopsy because their doctor suspects rejection. Researchers want to see if a simple blood or urine test can detect rejection, which might make future biopsies less necessary.
RouenAges 18 years+ - NCT06795958Recruiting
Detecting heart rejection without a biopsy in children
This trial tests if a special MRI can detect early signs of heart rejection in children and young adults who have had a heart transplant. If successful, it might reduce the need for invasive biopsies.
BolognaAges Up to 18 years - NCT06178744Recruiting
AI in heart transplant ultrasound study
This study uses artificial intelligence to look at echocardiograms (ultrasounds of the heart) from heart transplant patients. It aims to see if AI can help predict rejection or other problems, potentially reducing the need for biopsies.
Rochester, MinnesotaAges 18 years+ - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT05732779Recruiting
App-based check-ins to help teens take transplant medicines
This study tests a phone app that uses video check-ins (called directly observed therapy) to help adolescent heart-transplant patients take their immunosuppression medicines as prescribed. It may help reduce missed doses, which is important for protecting the transplanted heart.
Coral Gables, FloridaAges 10–21 - NCT05385432RecruitingPhase 3
Kidney transplant induction therapy for sensitized patients
This trial tests a specific “induction” treatment to help people who have stronger immune reactions from past sensitizing events during a kidney transplant. It may help improve how well the transplant works and how safely the immune system is managed.
ToursAges 18–79 - NCT05499637RecruitingPhase 2
PET/CT scan using a special tracer for heart inflammation
This Phase 2 study tests whether a PET/CT scan using a radioactive tracer can help evaluate acute heart inflammation. It may help doctors better identify inflammation and guide follow-up, especially in people suspected of specific heart inflammation conditions or recently after heart transplant follow-up.
Lausanne, Canton of VaudAges 18 years+ - NCT05586906Recruiting
Breath test to detect lung transplant problems early
This trial looks at a simple, noninvasive breath test to spot early lung transplant dysfunction after a lung transplant. Because it focuses on testing after the transplant, it may help your care team catch issues earlier.
ZurichAges 18 years+ - NCT04870437Recruiting
Light therapy study for kidney transplant rejection immune cells
This study looks at whether extra body light treatment (ECP) can change certain immune cells in people with a specific type of kidney transplant rejection caused by antibodies (cABMR). It’s meant to see if ECP could help manage the immune process after transplant.
BesançonAges 18 years+ - NCT04787822Enrolling by invitation
Follow-up for people in a lung transplant research group
This study checks long-term health and well-being in people who previously joined a lung transplant research study. It may help doctors understand long-term changes after transplant and improve future care.
Birmingham, AlabamaAges 13 years+
Hear when a new Rejection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for rejection?
- Yes. Clin2 currently lists 103 recruiting rejection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rejection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rejection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.