Clinical trials
Relapsed or Refractory Multiple Myeloma (RRMM) clinical trials
Below are recruiting relapsed or refractory multiple myeloma (rrmm) clinical trials, each written for real people, not researchers. We’re tracking 1,262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07604909RecruitingPhase 2
Serplulimab plus chemotherapy for early-relapsed colorectal cancer
This trial tests a new immunotherapy drug called serplulimab combined with standard chemotherapy or targeted therapy for colorectal cancer that has come back within a year after surgery. The goal is to see if adding this immune-boosting drug helps control the cancer better than chemotherapy alone.
ShanghaiAges 18 years+ - NCT07614321RecruitingPhase 4
Silodosin for Bladder Symptoms in Women With MS
This study tests whether silodosin, a medication that relaxes bladder muscles, can help women with multiple sclerosis who have bothersome urinary symptoms. The goal is to see if it can reduce urgency, frequency, and other lower urinary tract problems.
Morristown, New JerseyAges 18 years+ - NCT07615725Recruiting
Dry Needling for Lower Leg Pain in Multiple Sclerosis
This study tests whether dry needling—a technique using thin needles to treat muscle pain—can help reduce lower leg pain in people with multiple sclerosis. Researchers want to see if this treatment can safely improve pain and function.
Tampa, FloridaAges 18–80 - NCT07648277Recruiting
Spine Position, Movement, and Balance in Multiple Sclerosis
This study examines how multiple sclerosis affects your spine alignment, flexibility, and balance. Understanding these changes may help develop better physical therapies and support for people living with MS.
Ankara, ÇubukAges 18–65 - NCT07567989Enrolling by invitation
Home Exercise and Brain Stimulation for MS Fatigue
This study tests whether doing exercises at home combined with a non-invasive brain stimulation technique (gentle electrical stimulation on your scalp) can reduce the exhaustion and tiredness that comes with multiple sclerosis. The goal is to see if this combination helps you feel less fatigued and improves your ability to stay active.
A Coruña, A CoruñaAges 18–75 - NCT07564921Enrolling by invitation
Nutrition and Muscle Strength in Multiple Sclerosis With Swallowing Difficulty
This study looks at how nutritional status and muscle function relate to each other in people with multiple sclerosis who have difficulty swallowing. Understanding this connection may help doctors better support patients with MS who struggle with eating and drinking.
Gaziantep, şehitkamilAges 18–65 - NCT07462338Enrolling by invitation
Walking test reliability in multiple sclerosis patients
This study checks how reliable a simple walking test (Timed Up and Go) is for people with multiple sclerosis, especially when they do another task at the same time. It aims to improve how doctors measure walking ability.
Gaziantep, GaziantepAges 18–65 - NCT07074587Enrolling by invitation
Spinal stabilization exercise for MS-related bladder symptoms
This trial tests whether spinal stabilization exercises can improve bladder control and pelvic floor function in women with multiple sclerosis. If you have mild to moderate MS and bladder issues like urgency or leaking, this study may help you.
Merkez, BoluAges 18–65 - NCT06955962Enrolling by invitation
Mandala art therapy for multiple sclerosis symptoms and quality of life
This trial tests whether creating mandala art can help improve symptoms and quality of life for people with multiple sclerosis. You would participate in art sessions while continuing your regular MS care.
TrabzonAges 18–65 - NCT06873464Enrolling by invitation
Brain stimulation to reduce fatigue in multiple sclerosis
This trial tests if a gentle brain stimulation technique (tDCS) can help reduce fatigue and improve quality of life for people with multiple sclerosis. You would receive either real or placebo stimulation over several sessions to see if it helps you feel less tired.
MadridAges 18–75 - NCT06849960Enrolling by invitation
Reliability and validity of the Two-minute Test for Multiple Sclerosis
This study tests whether a simple two-minute walking test is a reliable way to measure function in people with multiple sclerosis. It aims to help doctors and patients understand the true value of this quick, easy test.
Şehitkamil, GaziantepAges 18–65 - NCT06261528Enrolling by invitationPhase 1
Light therapy for sleepiness in progressive MS
This trial tests whether a special light therapy can help people with progressive multiple sclerosis who feel sleepy during the day. It aims to improve energy, mood, and sleep patterns.
Dallas, TexasAges 18 years+ - NCT04415372Enrolling by invitation
MRI brain scan study for white and gray matter in MS
This study uses detailed MRI scans to look at brain “white matter” and “gray matter” changes in people with multiple sclerosis (MS). It may help researchers better understand how MS affects the brain and relates to symptoms.
Madison, WisconsinAges 18–60 - NCT03032601Enrolling by invitation
N-acetyl cysteine study for people with multiple sclerosis
This study tests whether N-acetyl cysteine (a supplement-like medicine) changes body and brain function in people with multiple sclerosis. It may help researchers understand how it affects brain chemistry and activity using special brain imaging.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07132775Recruiting
Full-body electrical stimulation suit for spasticity and pain
This study tests a full-body suit that delivers gentle electrical pulses to help reduce muscle stiffness, spasms, and pain in people with conditions like multiple sclerosis, fibromyalgia, or other neurological problems. It may help with movement and comfort.
Chicago, IllinoisAges 18–75 - NCT07257419RecruitingPhase 1
CAR T cells and stem cell transplant for leukemia and lymphoma
This trial tests giving special immune cells (CAR T cells) after a half-matched stem cell transplant. It's for children and young adults with high-risk leukemia or lymphoma that has come back or not responded to treatment.
Memphis, TennesseeAges Up to 21 years - NCT06676059Recruiting
Substance use monitoring study with a smartphone app
This study uses a smartphone app and daily surveys to track alcohol or drug use. It aims to create a database for future research on addiction patterns and recovery.
Baltimore, MarylandAges 18–120 - NCT06687772RecruitingPhase 2
Preventing brain relapse in high-risk lymphoma with stem cell transplant
This trial tests if high doses of chemotherapy (thiotepa and carmustine) followed by a stem cell transplant from your own cells can prevent lymphoma from coming back in the brain or spinal cord. It's for people with aggressive lymphoma that has a higher risk of spreading to the central nervous system.
St Louis, MissouriAges 18–75 - NCT07788859Recruiting
Testing dual-task walking tests in multiple sclerosis
This study looks at how well three different dual-task tests (doing two things at once while walking) work for people with multiple sclerosis. It aims to find reliable and valid ways to assess walking and thinking in MS.
GaziantepAges 18–65 - NCT07439211RecruitingPhase 1
Testing a new drug combo for acute myeloid leukemia
This trial tests a new drug, eganelisib, combined with azacitidine and venetoclax for patients with acute myeloid leukemia (AML). It's for people whose AML has come back or hasn't responded to treatment, or for those with a high-risk type who haven't been treated yet.
Boston, MassachusettsAges 18–90 - NCT04322318RecruitingPhase 2
Study of combination chemotherapy for Wilms tumor in children
This Phase 2 trial tests combination chemotherapy for children with certain types of Wilms tumor—either newly diagnosed diffuse anaplastic Wilms tumor or favorable Wilms tumor that has come back. The goal is to see how well the treatment controls the tumor and is tolerable for children.
Birmingham, AlabamaAges Up to 30 years - NCT04838041RecruitingPhase 2
Testing stopping treatment after asciminib for CML relapse
This trial looks at whether people with chronic-phase CML who tried stopping a prior CML medicine and had to restart can later stop treatment again after a set period using asciminib. It checks whether you can stay in a deep remission (“free remission” without the usual CML tablets).
Detroit, MichiganAges 18 years+ - NCT05183035RecruitingPhase 3
Testing venetoclax for children with relapsed AML
This study tests a drug called venetoclax in children and young adults whose acute myeloid leukemia (AML) has returned after treatment. The drug may help block cancer cell growth. The study also looks at safety and how well the drug works when given alone or with other treatments.
Phoenix, ArizonaAges 4 weeks–21 years - NCT07003295RecruitingPhase 2
Glofitamab for mantle cell lymphoma that returned after CAR-T
This trial tests a new drug, glofitamab, for mantle cell lymphoma that came back or didn’t respond after CAR-T cell therapy. It aims to see if glofitamab can shrink or control the lymphoma.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for relapsed or refractory multiple myeloma (rrmm)?
- Yes. Clin2 currently lists 1,262 recruiting relapsed or refractory multiple myeloma (rrmm) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a relapsed or refractory multiple myeloma (rrmm) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a relapsed or refractory multiple myeloma (rrmm) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.