Clinical trials
Renal Cell Carcinoma (Kidney Cancer) clinical trials
Below are recruiting renal cell carcinoma (kidney cancer) clinical trials, each written for real people, not researchers. We’re tracking 167 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05753839Recruiting
Testing surgery plus immunotherapy for metastatic kidney cancer
This trial studies whether removing the kidney tumor (cytoreductive nephrectomy) before treatment can improve outcomes for people with metastatic clear-cell kidney cancer. All participants are expected to receive standard immunotherapy (nivolumab plus ipilimumab), and the study focuses on the role of surgery in the “immuno-oncology era.”
SeoulAges 18 years+ - NCT06211790RecruitingPhase 2
Targeted first-line treatment for advanced kidney cancer based on protein profile
This trial tests a first-line precision treatment for clear cell kidney cancer that has spread or cannot be removed. It aims to match the treatment to your cancer's protein profile to improve outcomes.
ShanghaiAges 18–75 - NCT03414827Recruiting
Genetic testing study for kidney cancer
This study looks at genetic features of kidney cancer by testing tumor samples. The goal is to find biomarkers—specific signs—that may help predict what kind of kidney cancer it is.
RoskildeAges Any age - NCT07872553RecruitingEarly Phase 1
Kidney cancer treatment preference study
This study looks at how kidney cancer patients feel about getting their treatment at home versus at the clinic, and asks their doctors for their views too. It is for patients already on certain standard treatments and aims to understand preferences that may improve care.
Basking Ridge, New JerseyAges 18 years+ - NCT06399419RecruitingPhase 1
Study of CBM588 with immunotherapy for advanced kidney cancer
This trial tests whether adding a probiotic (CBM588) to a standard immunotherapy combination (nivolumab and ipilimumab) helps treat advanced kidney cancer. It is for people with a specific type of kidney cancer that has spread or cannot be removed with surgery, who have not had systemic treatment before.
Duarte, CaliforniaAges 18 years+ - NCT07833085Recruiting
Imaging test for solid tumors using a special tracer
This study tests a new imaging method that uses a special tracer to find solid tumors in the body. It may help doctors see tumors more clearly and guide treatment.
Wuhan, HubeiAges 18 years+ - NCT07820566Recruiting
Personalized 3D tumor model for kidney, bladder, and prostate cancers
This study uses your tumor sample to build a personalized 3D model that mimics how your cancer grows. The goal is to better understand these cancers and potentially find more effective treatments in the future.
StrasbourgAges 18 years+ - NCT07805122Recruiting
Monitoring cabozantinib levels to manage side effects in kidney cancer
This study looks at whether closer monitoring of cabozantinib levels in the blood can help doctors manage side effects better. It's for people with advanced kidney cancer who are already planning to take cabozantinib.
Aviano, PordenoneAges 18 years+ - NCT07714018Recruiting
Comparing two weight loss programs for kidney cancer patients
This study tests two different weight loss programs to see which one helps prevent kidney cancer from growing in people with small kidney masses who are under active surveillance. It may help by improving overall health and potentially slowing cancer progression.
Buffalo, New YorkAges 18 years+ - NCT07704970Recruiting
Nerve block for pain relief in robotic kidney surgery
This trial tests a special nerve block called QLESP to control pain after robotic partial kidney removal. It may reduce the need for strong pain medicines and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07667335RecruitingPhase 1/Phase 2
Combination therapy for advanced bladder cancer
This trial tests a combination of three drugs for advanced bladder cancer (including cancer of the renal pelvis or ureter) that has not been treated before. The goal is to see if the combination is safe and effective.
Seattle, WashingtonAges 18 years+ - NCT07645690RecruitingEarly Phase 1
CD70 CAR-T Cell Therapy for Advanced Kidney Cancer
This early-stage trial tests a new type of cell therapy called CD70 CAR-T for advanced kidney cancer (clear cell renal cell carcinoma) that has spread or cannot be surgically removed. The therapy uses cells from your own immune system that are genetically modified to recognize and attack cancer cells.
BeijingAges 18–75 - NCT06690697RecruitingPhase 2
Toripalimab and JS004 for advanced kidney cancer
This trial tests a combination of two drugs, toripalimab and JS004, for patients with advanced kidney cancer that has returned or spread. It aims to see if this therapy can help when other treatments have stopped working.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07636148Recruiting
Registry of minimally invasive cancer treatment with advanced imaging
This study collects information from patients undergoing minimally invasive procedures to treat solid tumors (cancers) using advanced CT imaging guidance. Researchers want to understand how well this imaging technique helps doctors perform these procedures safely and effectively.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT07564232RecruitingPhase 1
LNK001 for Advanced Kidney Cancer After Prior Treatments
This Phase 1 trial tests a new cell therapy called LNK001 in patients with advanced clear-cell kidney cancer that has progressed despite prior immunotherapy and targeted drugs. The therapy is designed to recognize and attack cancer cells by targeting a protein called CAIX.
Houston, TexasAges 18 years+ - NCT07555210Recruiting
Bone Density Changes During Cancer Immunotherapy
This study tracks how a type of cancer treatment called anti-PD-1 immunotherapy affects bone strength over time. Researchers want to understand whether this treatment causes bone density loss and help develop ways to protect bones during cancer care.
Nashville, TennesseeAges 18 years+ - NCT07516366RecruitingPhase 2
Immunotherapy before surgery for clear cell kidney cancer
This trial tests whether giving two immunotherapy drugs before surgery can safely shrink kidney cancer tumors and help your body fight the cancer. You would receive the drugs before your scheduled surgery, and then your cancer would be removed as planned.
Irvine, CaliforniaAges 18 years+ - NCT07510334RecruitingPhase 2
VSV Virus Plus Immunotherapy for Advanced Kidney Cancer
This trial tests a combination of a special virus (VSV-IFNβ-NIS) with two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced clear cell kidney cancer that hasn't been treated yet. It aims to see if this approach helps shrink tumors or slow the disease.
Rochester, MinnesotaAges 18 years+ - NCT06769893Recruiting
New PET scan for kidney cancer staging and monitoring
This study tests a new type of PET scan that uses a tracer called 68Ga-RCCB6 to see kidney cancer more clearly. It compares this scan to another PET scan (68Ga-PSMA) to help doctors stage the cancer, check treatment response, and detect any return of the disease.
Xi'an, China, ShaanxiAges 18–75 - NCT07485114Recruiting
Galectin-3 levels in patients on immunotherapy for cancer
This study looks at a protein called galectin-3 in people with certain cancers who are getting immunotherapy (PD-1/PD-L1 inhibitors). It aims to see if galectin-3 levels can help predict how well the treatment works.
Tel Aviv, IsraelAges 18 years+ - NCT06364631RecruitingPhase 3
Testing a new approach for advanced kidney cancer
This trial is testing a new treatment for people with advanced kidney cancer that has spread to other parts of the body. It aims to find a better way to manage the disease.
ViennaAges 18 years+ - NCT07402109Recruiting
Precise guided radiation therapy for kidney cancer
This trial tests a new type of precise radiation therapy for kidney cancer. It uses a special scanner to guide the treatment without needing a marker, which may make the procedure quicker and more comfortable.
Rotterdam, South HollandAges 18 years+ - NCT07397611RecruitingPhase 2
Neoadjuvant immunotherapy for clear cell kidney cancer
This study tests a new combination of medications (casdatifan and zimberelimab) given before surgery to remove kidney tumors in people with clear cell renal cell carcinoma (ccRCC). The goal is to see if this approach can help shrink the tumor or improve outcomes.
Boston, MassachusettsAges 18 years+ - NCT07389629RecruitingPhase 2
Combination therapy before surgery for kidney cancer
This trial tests a new drug combination given before surgery for kidney cancer that is early stage but hard to operate on. The goal is to shrink the tumor and make surgery easier.
GuangzhouAges 18–80
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Renal Cell Carcinoma (Kidney Cancer) trials by city
Studies with a site in or near these metro areas.
Renal Cell Carcinoma (Kidney Cancer) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for renal cell carcinoma (kidney cancer)?
- Yes. Clin2 currently lists 167 recruiting renal cell carcinoma (kidney cancer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a renal cell carcinoma (kidney cancer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a renal cell carcinoma (kidney cancer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.