Clinical trials
Rheumatic Heart Disease clinical trials
Below are recruiting rheumatic heart disease clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05504928Recruiting
School program to prevent hidden heart valve disease
This study tests whether a prevention program done at a specific school can reduce how common “latent” (hidden) rheumatic heart disease is in children. If you attend the study’s school in Tulsipur, this program may be offered to help protect students’ heart health over time.
Tulsi̇̄purAges 5–16 - NCT05991219Recruiting
Rheumatic heart disease screening and prevention study
This study is looking for people living in rural areas of Sindh, Pakistan, to help screen for and prevent rheumatic heart disease. It aims to find and treat the condition early.
Karachi, SindhAges 10–30 - NCT07753681Recruiting
Chronic disease care in Zambia
This study helps improve care for people with long-term illnesses like diabetes or high blood pressure in Zambia. It aims to make sure you get regular check-ups and support.
Lusaka, Lusaka ProvinceAges Any age - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT07493603RecruitingPhase 1/Phase 2
Herbal medicine study for chest pain after stent placement
This trial tests a traditional Chinese herbal formula, Yiyang Huoluo Decoction, for people who still have chest discomfort after getting a stent for coronary heart disease. It aims to see if the herbal treatment can improve symptoms.
Huzhou, ZhejiangAges 50–75 - NCT07146048RecruitingPhase 3
Stopping penicillin for early rheumatic heart disease
This trial tests whether it is safe to stop taking daily penicillin for children and teens whose rheumatic heart disease has improved or stayed mild. If you took part in the GOALIE study and your heart condition is now stable, this study may help determine if you can safely stop medication.
Kampala, UGAges 5–20 - NCT04556188Recruiting
Study to improve cardiac surgery services for rheumatic heart disease
This study looks at whether building a better, sustainable cardiac surgery service can reduce the burden of rheumatic heart disease. It focuses on patients who need cardiac surgery at a specific hospital during a training and research program.
Addis AbabaAges 14 years+ - NCT06720272Recruiting
School program to prevent rheumatic heart disease
This study tests whether a program in schools can help prevent rheumatic heart disease in children. If your child is between 5 and 16 years old and attends a participating school, they may be able to join.
KathmanduAges 5–16 - NCT05783375Recruiting
Rheumatic heart prevention program for Ugandan communities
This study helps deliver prevention care for rheumatic heart disease in specific districts of northern Uganda. If you live there (or provide care in the selected clinics), the program may offer extra support to help stop heart damage before it starts.
Kampala, UgandaAges 5 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT07275580RecruitingPhase 4
Antibiotics before tooth removal for people with immune disorders
This trial tests whether taking preventive antibiotics before a simple tooth extraction helps prevent infections in people with weakened immune systems due to autoimmune diseases. It might help you avoid complications after your dental procedure.
São Paulo, São PauloAges 18 years+ - NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT07464132RecruitingPhase 1/Phase 2
New PET scan for detecting certain diseases
This trial uses a special PET scan tracer to see if it can help find and monitor diseases linked to a protein called FAP. It is for both cancer patients needing a biopsy and healthy volunteers.
Beijing, Beijing MunicipalityAges 18–85 - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT06778343Recruiting
Biomarkers study for inflammatory rheumatic diseases
This study is looking for people with ankylosing spondylitis, rheumatoid arthritis, or lupus to help find biomarkers that may make diagnosis easier. If you have one of these conditions and haven't tried biologic therapies, you may be able to join.
LisbonAges 18–65 - NCT07208058RecruitingPhase 3
Testing plonmarlimab for blood cell overactivation in people with rheumatic disease
This trial tests a new drug called plonmarlimab for people with a rheumatic (joint or immune) disease who also have a dangerous overreaction of their immune system called HLH (or MAS). The goal is to see if the drug can help when high-dose steroids have not worked or are not an option.
Beijing, Beijing MunicipalityAges 16–80 - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT07274124Recruiting
Pain education and nerve stimulation for rheumatoid arthritis
This study tests whether combining pain education with a mild nerve stimulation device can improve pain and recovery in people with rheumatoid arthritis. It may help you manage long-term pain better.
Istanbul, FatihAges 20–65 - NCT07184450RecruitingPhase 1
CAR-T cell therapy for children with hard-to-treat rheumatic diseases
This trial tests a new treatment using your child's own immune cells, modified to target B cells and fight severe rheumatic diseases like juvenile dermatomyositis, arthritis, scleroderma, or Sjogren's syndrome. It's for children who haven't improved with standard treatments.
Hangzhou, ZhejiangAges 5 years+
Hear when a new Rheumatic Heart Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for rheumatic heart disease?
- Yes. Clin2 currently lists 26 recruiting rheumatic heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatic heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatic heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.