Clinical trials
Rotator Cuff Tears of the Shoulder clinical trials
Below are recruiting rotator cuff tears of the shoulder clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07781553Recruiting
Shoulder tear repair healing study
This study looks at whether certain markers in your body can predict how well your shoulder tendon heals after surgery. It may help doctors know what to expect during recovery.
Iowa City, IowaAges 18–99 - NCT05067543Recruiting
Shoulder replacement study using a new humerus implant device
This study tests a specific device used for shoulder arthroplasty (shoulder replacement) in adults. You may be able to join if you need a shoulder replacement and meet safety checks around infection, bone quality, and allergies.
Lexington, KentuckyAges 18 years+ - NCT07587931Recruiting
Concentric vs Eccentric Exercise for Partial Rotator Cuff Tears
This study compares two types of shoulder exercises—one where you shorten the muscle and one where you lengthen it—to see which works better for partial tears of your rotator cuff (the muscles that stabilize your shoulder). The goal is to reduce pain and improve shoulder function.
Elâzığ, MErkezAges 18–65 - NCT05981833Recruiting
Donated skin graft for large rotator cuff tears
This study tests whether adding a donated skin graft during rotator cuff repair helps heal large tears better than repair alone. It may be an option for people with a first-time, large rotator cuff tear who have moderate to severe fatty changes in the muscle.
Scottsdale, ArizonaAges 30–75 - NCT05590494Recruiting
New treatment for partial rotator cuff shoulder tears
This trial tests a new approach for people with a partial (not full) tear of the rotator cuff, found on MRI. It may help improve shoulder function if your tear matches the study’s specific size and location rules.
Onalaska, WisconsinAges 25–75 - NCT03752034Recruiting
Muscle fragments after rotator cuff surgery to improve shoulder function
This study looks at whether using “muscle fiber fragments” during/after rotator cuff repair can help your shoulder work better. It targets people with a small tear in one shoulder who can follow the post-surgery follow-up plan.
Winston-Salem, North CarolinaAges 40–80 - NCT04571918Recruiting
Arthroscopic repair using a biodegradable spacer for severe shoulder tears
This study looks at an arthroscopic procedure (a minimally invasive surgery) that includes cleaning the tear and placing a biodegradable spacer to treat painful, severe rotator cuff tears. It may help reduce pain and improve shoulder function in people who have tried non-surgical treatments but still have symptoms.
ArendalAges 60–85 - NCT01193647Enrolling by invitation
Study genetics that may raise rotator cuff injury risk
This study looks at genetic (inherited) factors that may make some people more likely to develop rotator cuff tears. You may be able to join if you’ve had a shoulder MRI for pain or you’re a close family member of someone with a documented tear.
Salt Lake City, UtahAges 18 years+ - NCT06741527Recruiting
Integrity Implant for rotator cuff repair study
This study is testing a new shoulder implant called the Integrity Implant System to see how well it works for people with rotator cuff tears. It may be a good fit if you need surgery to repair your torn tendon and meet the safety requirements.
Gilbert, ArizonaAges 18 years+ - NCT07219654RecruitingPhase 2
Study of TPX-115 for partial rotator cuff tear
This study tests an experimental treatment called TPX-115 for people with a partial-thickness rotator cuff tear. It aims to see if the treatment can reduce pain and improve function compared to standard care.
La Mesa, CaliforniaAges 18 years+ - NCT07004218Enrolling by invitation
Ultrasound follow-up after massive rotator cuff tear surgery
This trial uses ultrasound imaging to check how the shoulder heals over the first year after surgery for a large tear in the rotator cuff (the group of tendons that helps lift and rotate your arm). The goal is to better understand recovery and improve care for people with this injury.
Çankaya, AnkaraAges 18–80 - NCT07375277Recruiting
Biceps tendon transfer for large rotator cuff tears
This study tests a new surgical technique that uses your biceps tendon to help repair a large rotator cuff tear. It may be an option if you have not improved after at least 3 months of other treatments.
BalıkesirAges 18 years+ - NCT07448584Recruiting
Study of shoulder repair with Lok™ suture anchors
This trial tests how well Lok™ suture anchors work for repairing certain shoulder problems like rotator cuff tears, shoulder instability, or partial tears. It is for people whose MRI confirms the injury and who haven't had prior shoulder surgery on that side.
Valence, Auvergne-Rhône-AlpesAges 18 years+ - NCT06817616Recruiting
Rotator cuff repair with stem cells for large shoulder tears
This trial tests whether adding umbilical cord stem cells to standard arthroscopic rotator cuff repair helps heal large or massive tears better. It may be an option if you have had shoulder pain for at least three months and other treatments haven't worked.
Seoul, KoreaAges 19 years+ - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT06818448Recruiting
Comparing rotator cuff repair methods for small tears
This trial compares two surgical techniques for repairing small rotator cuff tears (up to 2 cm). It tests if a newer method helps people recover better than the standard approach.
MechernichAges 18 years+ - NCT06414005RecruitingPhase 2/Phase 3
TPX-115 injection for partial-thickness rotator cuff tear
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07324343Recruiting
Education for shoulder pain: which patients benefit most?
This study tests whether patients with different types of shoulder pain respond better to learning about their condition through education alone. You will receive information and advice to help you manage your pain without injections or surgery.
IstanbulAges 18–65 - NCT07208448Recruiting
Study on a new shoulder spacer for torn rotator cuff
This trial tests a new biodegradable spacer for the shoulder in people with a full-thickness rotator cuff tear. It may help relieve pain and improve shoulder function without the need for more invasive surgery.
AshdodAges 50 years+ - NCT07232511Recruiting
Cuff-assisted exercise for shoulder pain
This study tests whether using a blood pressure cuff during gentle shoulder exercises can help reduce pain and improve movement. It is for people with ongoing shoulder pain related to the rotator cuff (the muscles and tendons that help lift and rotate your arm).
Valencia, ValenciaAges 18–65 - NCT06848023Enrolling by invitation
Shoulder replacement vs tendon repair in older adults
This study compares how well two different shoulder surgeries—reverse total shoulder replacement and rotator cuff repair—work for people 60 and older, at least one year after the operation. If you meet the age and surgery requirements, your results could help doctors decide which procedure is better for older adults.
Germantown, TennesseeAges 60–95 - NCT07228936Recruiting
Pectoralis minor tightness and rotator cuff tears
This trial looks at whether tightness in a small chest muscle (pectoralis minor) is linked to rotator cuff tears. If you have a partial rotator cuff tear or a healthy shoulder, you might be able to join to help answer this question.
Ankara, CankayaAges 18–55 - NCT03617562Recruiting
Compare two surgeries for large rotator cuff tears
This trial compares two different operations to treat large, hard-to-repair rotator cuff tears. If your tear is too damaged to be repaired in the usual way, the study tests whether one surgical approach may work better than a partial repair.
Toronto, OntarioAges 18–65 - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80
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Common questions
- Are there clinical trials for rotator cuff tears of the shoulder?
- Yes. Clin2 currently lists 105 recruiting rotator cuff tears of the shoulder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff tears of the shoulder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff tears of the shoulder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.