Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06797531Recruiting
Ribociclib Real-World Study in Early Breast Cancer
This study observes people with early-stage hormone receptor positive, HER2-negative breast cancer who are taking ribociclib (Kisqali) with hormone therapy after surgery. It aims to see how well the treatment works and how safe it is in real life.
RiyadhAges 18–99 - NCT06779630Recruiting
Study of a 48mm drug-coated stent for long coronary artery blockages
This trial tests a longer-than-usual drug-coated stent (Orsiro Mission) for treating long blockages in heart arteries. It aims to see if the stent is safe and effective for people with coronary artery disease.
Concord, CaliforniaAges 18 years+ - NCT06771323RecruitingPhase 2
Adding valbenazine to botox for neck muscle spasms
This study tests if adding a daily pill (valbenazine) to regular botox injections can better reduce neck muscle spasms. It helps people whose botox works but may not be enough.
Richmond, VirginiaAges 18–75 - NCT06757764RecruitingPhase 4
Stroke from artery narrowing: testing combination of anti-platelet drugs
This trial tests whether a combination of two or three anti-platelet medicines (like aspirin, clopidogrel, or cilostazol) is safe and works better than one alone for people who had a stroke from a narrowed artery. The goal is to prevent another stroke.
Seoul, Songpa-guAges 20 years+ - NCT05631730RecruitingPhase 3
Flecainide plus metoprolol vs metoprolol alone for rhythm control
This trial studies whether adding flecainide to metoprolol can better reduce dangerous heart rhythm problems in people with mitral valve prolapse. It also checks safety and side effects compared with metoprolol alone.
OsloAges 18 years+ - NCT06734351RecruitingPhase 3
Comparing two gels for cheek fullness
This study tests a new injectable gel (NOA VOLUME) for restoring fullness in the cheeks, comparing it to an already-approved gel (JUVÉDERM VOLUMA XC). It's for adults with moderate to severe cheek hollowing who want a safe, effective option.
Birmingham, AlabamaAges 22 years+ - NCT06681051Recruiting
OSTENIL TENDON for tendon pain study
This study tests whether OSTENIL TENDON, a gel-like substance injected into the tendon, can safely reduce pain and improve movement in people with common tendon problems (like jumper's knee or tennis elbow). It may be a good option if other treatments haven't worked for you.
Berlin, State of BerlinAges 18–99 - NCT06669806Recruiting
TIPS Stent Graft for Cirrhosis Complications
This study tests a TIPS stent graft (a tiny mesh tube placed in the liver to relieve pressure) for people with cirrhosis and complications like bleeding or fluid buildup. It aims to see how well it works and if it's safe.
Changsha, HunanAges 18–75 - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT06676644Recruiting
Flu vaccine with booster for older adults with health conditions
This trial tests whether a flu vaccine with an extra ingredient (called an adjuvant) is safer and works better for older Asian adults with chronic health conditions than a standard flu vaccine. It aims to provide better protection against the flu for people like you.
TaipeiAges 65 years+ - NCT06663358Recruiting
Safety and effectiveness of Elfabrio in Fabry disease patients
This study is for people with Fabry disease who are taking or planning to take the medication Elfabrio (pegunigalsidase alfa). It will look at how safe and effective the treatment is in real-world use.
Birmingham, AlabamaAges 18 years+ - NCT06634589RecruitingPhase 1/Phase 2
Combination therapy for relapsed B-cell blood cancers
This study tests new drug combinations for people with B-cell blood cancers (like lymphoma or leukemia) that have come back or stopped responding to treatment. It aims to see if these combos are safe and can help fight the cancer.
Phoenix, ArizonaAges 18 years+ - NCT06620757Recruiting
Short-term single blood thinner after LAmbre device implant
This study tests whether it is safe and effective to use just one blood thinner (aspirin or clopidogrel) for a short time after getting a LAmbre device implanted to close off a heart pouch that can cause strokes. It is for people with atrial fibrillation who cannot take standard blood thinners long-term.
A CoruñaAges 18–100 - NCT06603558Recruiting
Preventing migraines with atogepant for Korean adults
This study tests a once-daily pill, atogepant, to see if it safely prevents chronic or episodic migraines in Korean adults. It's meant for people whose doctor has already prescribed the pill for migraine prevention.
Busan, Busan Gwang YeogsiAges 19 years+ - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06603246RecruitingPhase 1
Study of inhaled GDC-6988 for mucus lung diseases
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
Birmingham, AlabamaAges 18 years+ - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT06575192RecruitingPhase 3
Breast reconstruction study with ARTIA matrix
This study tests a new supportive mesh called ARTIA for women having breast reconstruction immediately after a mastectomy. The mesh is placed under the skin to help hold a breast implant in position during a two-stage reconstruction process.
Los Angeles, CaliforniaAges 18 years+ - NCT06202027Recruiting
CRYSVITA safety and effectiveness in Korean patients
This study looks at the safety and effectiveness of CRYSVITA (burosumab) in real-world use among patients in South Korea. If you are already prescribed CRYSVITA for X-linked hypophosphatemia, your doctor may ask you to join this survey to help track how well it works and any side effects.
Wŏnju, Gangwon-doAges 1 day+ - NCT06562270Recruiting
Teens with severe alopecia areata: treatment safety study
This study tracks the safety and effectiveness of alopecia areata treatments in teenagers aged 12-17. It helps doctors understand which treatments work best and are safest for young people with severe hair loss.
Waltham, MassachusettsAges 12–17 - NCT06499363Recruiting
Treprostinil for pulmonary hypertension in newborns
This study collects information on how well a medicine called treprostinil works and how safe it is for newborn babies with pulmonary hypertension (high blood pressure in the lungs). It is for babies who have already received this treatment as part of their regular care.
BronAges Up to 10 months - NCT06541847RecruitingPhase 2
Testing HLX-1502 for NF1 with Plexiform Neurofibromas
This trial tests an experimental drug called HLX-1502 for people with NF1 who have a plexiform neurofibroma (a type of nerve tumor) that is growing or causing problems. It aims to see if the drug is safe and can shrink or stop the tumor from worsening.
Birmingham, AlabamaAges 12 years+ - NCT06548204RecruitingPhase 2
Antihistamine after a heart attack
This trial tests whether taking an antihistamine medicine called fexofenadine hydrochloride can help people recover better after a heart attack. It is a randomized study, so some participants will receive the medicine and others will receive a placebo (a pill with no active ingredients).
Hangzhou, ZhejiangAges 18 years+ - NCT06517264Enrolling by invitation
Treating mild diverticulitis without antibiotics as an outpatient
This trial tests if mild diverticulitis (a small infection in the colon) can be safely treated at home without antibiotics. If you have this condition and are otherwise healthy, you may be able to avoid a hospital stay.
MurciaAges 18–80
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.