Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 397 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06625749Recruiting
AccuraSee lens implant to improve near vision after cataract surgery
This trial tests an artificial lens (AccuraSee IOPCL) placed inside your eye to help you see better up close and at intermediate distances after having cataract surgery. It is for people who still need reading glasses and have a specific type of monofocal lens already in their eye.
Cleveland, OhioAges 22 years+ - NCT06634589RecruitingPhase 1/Phase 2
Study of a new drug combo for returning B-cell blood cancers
This trial tests a new drug combination for people with B-cell blood cancers (like lymphoma or leukemia) that have returned or stopped responding to treatment. It aims to find out if the combination is safe and works better than current options.
Phoenix, ArizonaAges 18 years+ - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT06662630Recruiting
Oscillatory ventilation study for ICU patients on breathing machines
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06663358Recruiting
Safety and effectiveness of Elfabrio in Fabry disease patients
This study is for people with Fabry disease who are taking or planning to take the medication Elfabrio (pegunigalsidase alfa). It will look at how safe and effective the treatment is in real-world use.
Birmingham, AlabamaAges 18 years+ - NCT06664918Recruiting
Milk ladder therapy for children with cow's milk allergy
This study tests whether a gradual 'milk ladder' approach (slowly introducing milk in increasing amounts) is safe and effective for children with cow's milk allergy. It may help your child eventually tolerate milk.
WarsawAges 1–5 - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT06676644Recruiting
Flu vaccine with booster for older adults with health conditions
This trial tests whether a flu vaccine with an extra ingredient (called an adjuvant) is safer and works better for older Asian adults with chronic health conditions than a standard flu vaccine. It aims to provide better protection against the flu for people like you.
TaipeiAges 65 years+ - NCT06681051Recruiting
OSTENIL TENDON for tendon pain study
This study tests whether OSTENIL TENDON, a gel-like substance injected into the tendon, can safely reduce pain and improve movement in people with common tendon problems (like jumper's knee or tennis elbow). It may be a good option if other treatments haven't worked for you.
Berlin, State of BerlinAges 18–99 - NCT06702813Recruiting
High-frequency vibration breathing treatment for ICU patients
This trial tests a device called MetaNeb that delivers high-frequency vibrations to help clear mucus and open collapsed air sacs in the lungs. It is designed for patients in the ICU who are awake, alert, and have trouble breathing or need extra oxygen.
Shanghai, Shanghai MunicipalityAges 1.5 years–80 years - NCT06707194RecruitingPhase 4
Penicillin plus etanercept for spondyloarthritis
This trial tests whether adding a common antibiotic (benzathine penicillin) to a standard biologic drug (etanercept) can better treat spondyloarthritis. It may help if you have active disease and are free of certain infections.
Hefei, AnhuiAges 18–59 - NCT06708156RecruitingPhase 3
Low-dose atropine drops to slow childhood nearsightedness
This trial tests two low-dose atropine eye drops (0.01% and 0.02%) to see if they can safely slow down the worsening of nearsightedness (myopia) in children. Your child would receive either one of these drops or a placebo (an inactive drop) once daily for up to 2 years.
Hefei, AnhuiAges 6–12 - NCT06720870Recruiting
Siltuximab for Castleman's disease: a real-world study
This trial is looking back at the medical records of people with a rare condition called Castleman's disease to see how well the drug Siltuximab worked for them in everyday hospital care, not in a research setting. The goal is to learn more about how safe and effective the drug can be for patients in real life.
Bologna, BolognaAges 18 years+ - NCT06731985Recruiting
Shorter sling tape follow-up study
This study looks at how well and how safely a shorter type of sling tape (used to treat stress urinary incontinence) works over time. It may help women who had this specific surgery between 2009 and 2020 understand their long-term results.
LorenskogAges 25–90 - NCT06757764RecruitingPhase 4
Stroke from artery narrowing: testing combination of anti-platelet drugs
This trial tests whether a combination of two or three anti-platelet medicines (like aspirin, clopidogrel, or cilostazol) is safe and works better than one alone for people who had a stroke from a narrowed artery. The goal is to prevent another stroke.
Seoul, Songpa-guAges 20 years+ - NCT06758609Recruiting
Brain cooling plus clot removal for large artery stroke
This trial tests a new treatment that combines cooling the brain with a catheter and removing the clot to restore blood flow — for people who have had a major stroke in the front part of the brain within the last 24 hours.
Guangzhou, GuangdongAges 18–85 - NCT06762782RecruitingPhase 2
Lenvatinib after liver cancer surgery to prevent recurrence
This trial tests whether taking lenvatinib after liver cancer surgery can lower the chance of the cancer coming back. It is for people who have a high risk of recurrence and have recently had their liver tumor completely removed.
Nanjing, JiangsuAges 18–80 - NCT06782373RecruitingPhase 2
Pacritinib for treating VEXAS syndrome
This trial tests a drug called pacritinib for people with VEXAS syndrome. It aims to see if pacritinib can help control inflammation and reduce the need for steroids. You may qualify if you have a specific UBA1 gene mutation and are currently on a stable steroid dose.
Scottsdale, ArizonaAges 18 years+ - NCT06782789Recruiting
Study of Tafasitamab and Lenalidomide for aggressive B-cell lymphoma
This study looks back at medical records of people with relapsed or refractory diffuse large B-cell lymphoma who received a combination of two drugs (tafasitamab and lenalidomide) through a special access program. The goal is to learn how well the treatment worked and what side effects occurred.
Bologna, BolognaAges 18 years+ - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06797531Recruiting
Ribociclib Real-World Study in Early Breast Cancer
This study observes people with early-stage hormone receptor positive, HER2-negative breast cancer who are taking ribociclib (Kisqali) with hormone therapy after surgery. It aims to see how well the treatment works and how safe it is in real life.
RiyadhAges 18–99 - NCT06804057Recruiting
SLE drug safety registry for adults with lupus
This registry tracks the safety and effectiveness of lupus treatments over time. If you have SLE and are starting a new treatment or were recently diagnosed, joining helps doctors learn which medicines work best.
Waltham, MassachusettsAges 18 years+ - NCT06808685Recruiting
Study of Elovie for advanced colorectal cancer
This study looks at how well a biosimilar version of bevacizumab (Elovie) works in people with advanced colorectal cancer that has spread and cannot be surgically removed. It aims to see if Elovie is safe and effective when used as the first treatment for this cancer.
Vitória, Espírito SantoAges 18 years+ - NCT06809764Recruiting
Study of T-DXd in Chinese patients with HER2m NSCLC
This study looks at how safe and effective the drug T-DXd (trastuzumab deruxtecan) is for Chinese patients with a specific type of lung cancer that has a HER2 mutation. It helps understand if this treatment works well in real-world settings.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 397 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.