Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06293378Recruiting
Sulfasalazine for liver fibrosis and cirrhosis
This study tests if sulfasalazine, a medicine already used for other conditions, is safe and helpful for people with liver scarring (fibrosis or cirrhosis). It is for patients with cirrhosis caused by certain liver diseases, like PBC, hepatitis B, hepatitis C, or alcohol use.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07376590Recruiting
Flow diverter stent study for brain aneurysms
This trial tests a flow-diverting stent for treating certain brain aneurysms located in distal parts of the brain's arteries. It’s for people who have already received this stent and are between 18 and 80 years old.
Hangzhou, ZhejiangAges 18–80 - NCT07367100Recruiting
Testing a new clot-removal catheter for stroke
This study tests a special catheter (a thin tube) designed to remove blood clots from large arteries in the brain during a stroke. The goal is to see if it is safe and effective at restoring blood flow.
EdegemAges 18–90 - NCT07355543Recruiting
Freezing device for skin tags: test of a new pen
This trial tests a new cryogenic pen that freezes off skin tags to see if it works better than an existing device. It may be an option if you have small, soft, skin-colored skin tags in certain body areas.
VilleurbanneAges 22 years+ - NCT07347938Recruiting
Tetanus prevention after injury: study of siltartoxatug
This study compares a new tetanus shot (siltartoxatug) with standard tetanus treatments to see if it works as well. It is for people aged 18 and older who need tetanus protection after an injury.
Hangzhou, ZhejiangAges 18 years+ - NCT07347600Recruiting
Studying inavolisib for a type of advanced breast cancer
This study tests a targeted therapy called inavolisib for people whose breast cancer has spread (advanced or metastatic), is hormone receptor-positive and HER2-negative, has a PIK3CA mutation, and has stopped responding to hormone therapy. It aims to see if inavolisib is safe and works well for them.
Xiamen, FujianAges 18 years+ - NCT07323342Recruiting
Hyaluronic acid plus fibrinogen for knee arthritis
This study tests whether a combination of two natural substances—hyaluronic acid (a joint lubricant) and fibrinogen (a blood protein that helps healing)—given as an injection into the knee, can safely reduce pain and improve function in people with knee osteoarthritis. It is for Vietnamese patients who have not recently used certain painkillers or had other knee treatments.
Ho Chi Minh CityAges 45–75 - NCT07316270Recruiting
Catheter ablation for atrial fibrillation after brain bleeding
This trial studies a procedure called catheter ablation to treat atrial fibrillation (an irregular heartbeat) in people who have had a brain hemorrhage. The procedure aims to reduce stroke risk and improve heart rhythm without increasing bleeding risk.
Hefei, AnhuiAges 18 years+ - NCT07309822Recruiting
Beltaven® venom allergy immunotherapy study
This study tests a treatment called Beltaven® for people with severe allergic reactions to bee, wasp, or hornet stings. It aims to see if the treatment is safe and helps prevent future reactions.
Barcelona, BarcelonaAges 14 years+ - NCT07298421RecruitingPhase 3
Testing afimkibart for children with Crohn's disease
This trial tests a medicine called afimkibart for children with moderately to severely active Crohn's disease. It aims to see how well the drug works and how safe it is when used for both starting and ongoing treatment.
New York, New YorkAges 2–17 - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT07296497Recruiting
Acupuncture for stubborn rosacea: safety and effectiveness
This trial tests whether acupuncture can help people with rosacea that hasn't improved with standard treatments like oral antibiotics or light therapy. If you have persistent redness or flushing that affects your daily life, this study may offer a new option.
Changsha, HunanAges 18–65 - NCT06664918Recruiting
Milk ladder therapy for children with cow's milk allergy
This study tests whether a gradual 'milk ladder' approach (slowly introducing milk in increasing amounts) is safe and effective for children with cow's milk allergy. It may help your child eventually tolerate milk.
WarsawAges 1–5 - NCT07284121Recruiting
Patient satisfaction and safety of Atezolizumab in routine care
This study tracks how well Atezolizumab (Tecentriq) works for people with certain lung or liver cancers in everyday medical practice. It helps doctors understand if patients are satisfied with their treatment and how it affects their quality of life.
KremsAges 18 years+ - NCT07280247Recruiting
AlphaVac System for Treating Acute Pulmonary Embolism
This study tests a device that suctions blood clots from the lungs in people with a moderate-risk pulmonary embolism. The goal is to see if it is safe and effective at removing clots and improving blood flow.
Saint Cloud, MinnesotaAges 18 years+ - NCT07275827RecruitingPhase 3
Testing 3 treatments for H. pylori infection
This study compares two different acid-reducing medications, given with or without zinc, to see which is safer and works best for treating H. pylori. All treatments are combined with two antibiotics.
Shibīn al KawmAges 19 years+ - NCT07271342Recruiting
Tracking tenecteplase for stroke in real-world settings
This study is collecting information on stroke patients who received the clot-dissolving drug tenecteplase. It aims to see how well the drug works and how safe it is in everyday hospital care in China.
BeijingAges 18 years+ - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07234591Recruiting
Study of an oral medication for moderate to severe plaque psoriasis
This study tests an experimental oral medication (a TYK2 inhibitor) for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing psoriasis symptoms.
ShanghaiAges 18–70 - NCT06907056RecruitingPhase 4
A study on a simpler HIV medication combination
This study tests if a two-drug HIV regimen (darunavir/cobicistat plus lamivudine) works as well as a standard three-drug regimen in men whose HIV is already well-controlled. If effective, this could mean taking fewer medications.
Mexico City, Mexico CityAges 18–70 - NCT07227532Recruiting
Testing a new catheter for atrial fibrillation treatment
This study tests a new catheter system, called Varipulse, to see if it's safe and effective for treating atrial fibrillation (AF), a heart rhythm problem. People with short-lasting AF who haven't been helped by medication may be able to join.
Phoenix, ArizonaAges 22 years+ - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT07229430Recruiting
Ultrasound treatment for loose neck and chin skin
This study tests a high-intensity focused ultrasound (HIFU) device to lift and tighten loose skin under the chin and neck. If you are in good health and want a non-surgical option for mild to moderate skin laxity, this trial may be for you.
Los Angeles, CaliforniaAges 30–65 - NCT07217509Enrolling by invitation
Myasthenia gravis drug safety registry
This study tracks the safety and effectiveness of newer drugs for myasthenia gravis. If you have started or are about to start a new medication for MG, this registry can help doctors learn more about how well these treatments work in real life.
Waltham, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.