Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Glendale, ArizonaAges 45 years+ - NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT07218549RecruitingPhase 1
Study of psychoactive substances in people with past opioid use
This trial tests how safe certain psychoactive substances are and what effects they have in people who have used opioids in the past but are not currently dependent on them. It aims to gather information that could help future treatment options.
Houston, TexasAges 18–55 - NCT07215754Recruiting
Real-world study of anifrolumab for active lupus
This study tracks how well anifrolumab works and how safe it is for people with active lupus. It's a real-world look at the drug's effects, so no additional treatments or tests are required beyond what your doctor already prescribes.
PisaAges 18 years+ - NCT07207369RecruitingPhase 3
Study of an injectable gel for atrophic acne scars
This study tests an injectable gel called ELAPR002f for treating moderate to severe atrophic acne scars on the cheeks. If you have rolling or boxcar scars and are in good general health without active acne or other skin issues, this trial may help improve your scars.
Glendale, ArizonaAges 22 years+ - NCT05986669Recruiting
DSP dental implant safety study for tooth loss
This trial tests several types of DSP dental implants to see if they are safe and work well for people with missing teeth. It is for patients who have had tooth loss for at least three months and are in good overall health.
Campo Largo, ParanáAges 18–70 - NCT07194265Recruiting
A study of the DurAVR heart valve for aortic stenosis
This trial tests a new heart valve called DurAVR for people with severe aortic stenosis (a narrowed aortic valve) who need a valve replacement. It compares the new valve to standard valves to see if it is safe and works well.
Copenhagen, Capital Region of DenmarkAges 18 years+ - NCT07201051RecruitingPhase 2
Testing a new drug for people with bronchiectasis
This trial tests if a new drug, GSK3862995B, is safe and effective for adults with bronchiectasis. It might help reduce lung infections and improve symptoms.
Mobile, AlabamaAges 18–85 - NCT07197164RecruitingPhase 2
Remdesivir for kidney transplant patients with mild COVID-19
This trial tests whether giving remdesivir to kidney transplant patients who test positive for COVID-19 can prevent them from getting severely ill. It is for people who have already had at least three COVID-19 vaccine doses and are scheduled to receive a kidney transplant soon.
Badalona, BarcelonaAges 18 years+ - NCT06519149Recruiting
Device for sleep apnea without CPAP
This trial tests a device placed in your mouth during sleep to treat obstructive sleep apnea. It may be an option if you cannot or do not want to use a CPAP machine.
Austin, TexasAges 18 years+ - NCT07187297Recruiting
Radiofrequency skin tightening study for loose skin and wrinkles
This study tests a radiofrequency device called Thermage® FLX to see how well it tightens skin and reduces wrinkles on the neck, face, belly, or upper arms. It may be a good option if you have mild to moderate skin looseness or lines and haven't had recent cosmetic procedures.
Sacramento, CaliforniaAges 30–60 - NCT06946901RecruitingPhase 2
Heated chemo in abdomen plus IV chemo for pancreatic cancer
This trial tests a treatment that combines heating chemotherapy drugs and delivering them directly into the abdomen (HIPEC) with standard chemotherapy through a vein. It is for people whose pancreatic cancer has spread to the lining of the abdomen but not to other organs, and who have not had prior cancer treatment.
Changsha, HunanAges 18–80 - NCT07173751RecruitingPhase 3
Pumitamig for advanced triple-negative breast cancer
This study tests a new drug called pumitamig for people with a type of breast cancer that is triple-negative or has very low hormone receptors and has come back or spread. It aims to see if pumitamig works better than standard treatment and how safe it is for people who cannot get PD(L)-1 immunotherapy with chemo.
Springdale, ArkansasAges 18 years+ - NCT07169695RecruitingPhase 2
Comparing a new eye drop to cyclosporine for eye allergy in kids
This study tests a new eye drop (T1695) against cyclosporine for children with moderate to severe vernal keratoconjunctivitis, a type of eye allergy. It aims to see which treatment works better and is safer for reducing symptoms.
Kolkata, West BengalAges 4–17 - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT07163182RecruitingPhase 1
Safety study of nasal CHF6467 in healthy volunteers
This study tests a new medicine called CHF6467 given as a nasal spray. It looks at how safe the medicine is, how it is absorbed and removed from the body, and what side effects it might cause. Healthy volunteers aged 18 to 55 can take part.
SofiaAges 18–55 - NCT07147543RecruitingPhase 4
Study of a powered exercise device for walking problems
This trial tests if a motorized leg exercise machine can help improve walking and balance in adults with gait disorders. It may be suitable for people who have difficulty walking but can stand with or without help.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07147530RecruitingPhase 4
Powered exercise device for walking in hip disease
This study tests a new powered exercise device designed to help people with hip problems walk better. It may be a good option if you have hip osteoarthritis or avascular necrosis and can do some standing and walking with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07147491RecruitingPhase 4
Study of a powered exercise device after hip surgery
This study tests a powered exercise device to help people walk better after hip surgery. It's for adults who are medically stable and can sit and stand with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07135596Recruiting
OviTex PRS mesh for breast reconstruction after mastectomy
This study tests a special mesh called OviTex PRS used during immediate breast reconstruction after mastectomy. The goal is to see if it is safe and effective for supporting the new breast implant.
Tampa, FloridaAges 22–75 - NCT07139808Recruiting
A new glucose and ketone monitor for type 1 diabetes
This trial tests a new device that measures blood sugar and ketones continuously. It may help people with type 1 diabetes who use an insulin pump keep better track of their levels.
Shijiazhuang, HebeiAges 18 years+ - NCT07129694Enrolling by invitation
Testing a new lab-grown ligament for ACL repair
This study tests a new, lab-grown ligament made from biological tissue for ACL reconstruction. It may offer a regenerative option for people with a recent ACL tear who need surgery.
Hirosaki, AomoriAges 18–44 - NCT06252935Recruiting
Collagen membrane for gum and bone repair
This trial tests a new collagen membrane (FormaAid®) for repairing gum and bone damage from gum disease. It may help people with deep gum pockets and bone loss who are not smokers and have well-controlled health conditions.
Taipei, TaiwanAges 18–70
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.