Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07549516Recruiting
Asciminib for chronic myeloid leukemia in germany
This study tests whether the drug asciminib is safe and works well for people with chronic myeloid leukemia, compared to standard TKIs. You may join if you're newly diagnosed or have tried only one previous TKI treatment.
Baden-Baden, Baden-WurttembergAges 18–100 - NCT07543692Recruiting
Ultrasound-guided injection therapy for spine pain
This study tests whether using ultrasound imaging to guide a special injection treatment (pharmacopuncture) is safe and effective for people with spine-related neck or lower back pain that radiates into the arms or legs. The treatment is already being offered as routine care, and this study tracks how well it works.
Daejeon, DaejeonAges 19–69 - NCT06708156RecruitingPhase 3
Low-dose atropine drops to slow childhood nearsightedness
This trial tests two low-dose atropine eye drops (0.01% and 0.02%) to see if they can safely slow down the worsening of nearsightedness (myopia) in children. Your child would receive either one of these drops or a placebo (an inactive drop) once daily for up to 2 years.
Hefei, AnhuiAges 6–12 - NCT07542314RecruitingPhase 4
Gene therapy for Duchenne muscular dystrophy
This study is checking how safe and effective ELEVIDYS, a gene therapy for Duchenne muscular dystrophy, is when used in everyday clinics. It will help doctors understand more about the treatment's real-world effects and provide care for those who receive it.
Houston, TexasAges 4 years+ - NCT07539389Recruiting
Robot-Assisted Walking Training for Children With Cerebral Palsy
This study tests whether a robotic device called Bambini Kids can safely help children with cerebral palsy improve their walking and movement. The robot assists with gait training—guided walking practice—to see if it helps strengthen muscles and improve mobility.
Songpa, SeoulAges 2–10 - NCT07518615Recruiting
Safety and Effectiveness of Guided Dental Implant Surgery System
This trial tests a new computer-guided system (Straumann Dynamic Navigation Falcon) that helps dentists place dental implants more precisely. If you need one or more dental implants and have healthy gums and jaw, this study may help determine if this guided approach is safe and works well.
GhentAges 18 years+ - NCT06762782RecruitingPhase 2
Lenvatinib after liver cancer surgery to prevent recurrence
This trial tests whether taking lenvatinib after liver cancer surgery can lower the chance of the cancer coming back. It is for people who have a high risk of recurrence and have recently had their liver tumor completely removed.
Nanjing, JiangsuAges 18–80 - NCT06122285Recruiting
Bulevirtide for chronic hepatitis delta
This study tests a daily shot of Bulevirtide for people with long-term hepatitis delta and early-stage cirrhosis. It aims to see if the medicine is safe and works well.
Milan, MIAges 18 years+ - NCT07496840Recruiting
Speedboat UltraSlim in POEM for swallowing disorders
This study is testing a new device called Speedboat UltraSlim™ during a procedure called POEM (per-oral endoscopic myotomy), which is used to treat achalasia and other swallowing disorders. The goal is to see if the device is safe and works well for people already scheduled for this surgery.
Houston, TexasAges 18 years+ - NCT06775405RecruitingPhase 3
Testing a new RSV treatment for hospitalized babies
This study tests a medicine called AK0529 for babies and toddlers hospitalized with RSV. It aims to see if the drug helps them recover faster and is safe for this age group.
BeijingAges 1 month–2 years - NCT06782789Recruiting
Study of Tafasitamab and Lenalidomide for aggressive B-cell lymphoma
This study looks back at medical records of people with relapsed or refractory diffuse large B-cell lymphoma who received a combination of two drugs (tafasitamab and lenalidomide) through a special access program. The goal is to learn how well the treatment worked and what side effects occurred.
Bologna, BolognaAges 18 years+ - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06485206Recruiting
Hybrid disc replacement and fusion for two-level neck disease
This study tests a combination of a disc replacement (Mobi-C) and a spinal fusion (ACDF) for people with degenerative disc disease at two levels in the neck. The goal is to see if this approach is safe and effective for relieving pain and nerve symptoms.
Sacramento, CaliforniaAges 22–69 - NCT07444957Recruiting
Safety of a drug-coated balloon for heart artery blockages
This study tests a special balloon coated with a drug called sirolimus to open blocked heart arteries. It may be an option for people with coronary artery disease who need a less invasive treatment.
Vigo, PontevedraAges 18 years+ - NCT07444489Enrolling by invitationPhase 3
Long-term safety of felzartamab for kidney transplant rejection
This study checks the long-term safety of felzartamab for people who have had a kidney transplant and are dealing with antibody-mediated rejection or signs of inflammation in the kidney. It's for those who were already in a previous study and took at least one dose of felzartamab.
Los Angeles, CaliforniaAges 18–75 - NCT07442045Recruiting
Comparing combined vs single drug for ulcerative colitis
Researchers want to see if taking two medications together (upadacitinib and vedolizumab) works better than taking just upadacitinib alone for people with moderate to severe ulcerative colitis. This is a real-world study, meaning it looks at patients being treated in normal medical practice.
Foshan, GuangdongAges 18 years+ - NCT06809231Recruiting
Long-term follow-up of CartiONE for knee cartilage repair
This study follows people who had CartiONE treatment for a knee cartilage lesion more than 6 months ago. Researchers want to see how well the treatment works and how safe it is over 1 to 13 years.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07425171Recruiting
Testing a drug-coated balloon for long leg artery blockages
This trial is testing a special balloon coated with the drug paclitaxel to open up long blockages in the leg artery (femoropopliteal). The goal is to see if it is safe and effective for improving blood flow and symptoms like pain or ulcers.
Suwon, Gyeonggi-doAges 19–85 - NCT07409272RecruitingPhase 3
Study of setidegrasib with chemo for pancreatic cancer
This trial tests a new drug called setidegrasib, given with two types of chemotherapy (mFOLFIRINOX or NALIRIFOX), for people whose pancreatic cancer has spread and has a specific genetic change called KRAS G12D. The goal is to see if adding setidegrasib helps control the cancer better than chemo alone.
Tucson, ArizonaAges 18 years+ - NCT06823960Recruiting
Zanubrutinib for marginal zone lymphoma in Italy
This study checks how well and how safely zanubrutinib worked for people with marginal zone lymphoma who got the drug through a special access program in Italy. The goal is to learn more about the drug's real-world effects and help future patients.
Alessandria, AlessandriaAges 18 years+ - NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT07404761Recruiting
Moving your arm after stroke or TBI
This study tests a device that uses mild electrical pulses and augmented reality (a computer overlay on real life) to help people who have arm or hand weakness after a recent stroke or brain injury regain movement.
HaifaAges 18 years+ - NCT07404176RecruitingPhase 2
New radioactive drug for advanced neuroendocrine tumors
This trial tests a new radioactive drug, Terbium-161 DOTATATE, for people with advanced neuroendocrine tumors that have stopped responding to a similar treatment called Lu-177 DOTATATE. It aims to see if this new drug is safe and can help shrink tumors.
Mumbai, MaharashtraAges 18–70 - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.