Clinical trials
Sarcoma clinical trials
Below are recruiting sarcoma clinical trials, each written for real people, not researchers. We’re tracking 401 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07215611Recruiting
Financial stress after sarcoma surgery study
This study looks at financial problems patients may have after surgery for bone or soft tissue sarcoma. It aims to understand how treatment costs affect patients and help find ways to support them.
Houston, TexasAges Any age - NCT07193550RecruitingPhase 2
Testing Zanzalintinib for Advanced Bone Sarcomas
This trial tests a new drug called zanzalintinib for people with advanced or metastatic bone sarcomas that have not responded to standard treatments. It aims to see if the drug can help shrink or slow the growth of these tumors.
Houston, TexasAges 18 years+ - NCT07174427RecruitingPhase 3
Study of a new cell therapy for synovial sarcoma
This trial tests a new cell therapy called TBI-1301 (Mip-cel) for people with synovial sarcoma that has spread or come back after chemotherapy. It is designed to help your immune system attack the cancer cells that have a specific marker (NY-ESO-1).
Osaka, OsakaAges 18 years+ - NCT07156565RecruitingPhase 1
Study of actinium therapy for advanced soft tissue sarcoma
This trial is testing a new type of radiation therapy for advanced soft tissue sarcoma that has not responded to other treatments. The goal is to see if this therapy can shrink tumors and help control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07148193Recruiting
Quality of life for long-term sarcoma survivors
This study looks at the quality of life and medical care for people who have had sarcoma (including soft tissue, bone, or GIST) for at least 5 years. It aims to understand how survivors are doing and how their care can be improved.
Dresden, SaxonyAges 18 years+ - NCT07139990RecruitingPhase 1
Personalized radiotherapy for lung, brain, sarcoma, or head and neck cancers
This trial tests whether giving personalized radiotherapy alongside standard treatments can better control several types of cancer: small cell lung cancer, brain metastases, soft tissue sarcoma, and head and neck cancer. It aims to see if this approach helps patients live longer without their cancer growing or coming back.
Dallas, TexasAges 18 years+ - NCT07129005Enrolling by invitation
MRI-based tool to tell uterine sarcoma from fibroids
This trial uses MRI scans to see if a computer can tell the difference between uterine sarcoma (a rare cancer) and fibroids (non-cancerous growths). If you've already been diagnosed with one of these and had an MRI before surgery, you may be able to help.
Wuhan, HubeiAges 18 years+ - NCT05894018RecruitingPhase 2
Seed radiation plus fluzoparib for advanced soft tissue sarcoma
This trial tests whether combining seed radiation (iodine-125 placed in/near the tumor) with fluzoparib can better control advanced, hard-to-remove soft tissue sarcoma. It may help shrink tumors and slow progression, but you must meet several cancer, health, and safety requirements.
Guangzhou, GuangdongAges 18 years+ - NCT04072042RecruitingPhase 2
Test a VEGFR2 drug for sarcoma with lung lesions
This Phase 2 study tests a VEGFR2-targeted medicine in people with advanced or metastatic sarcoma whose cancer cannot be fully removed by surgery. It focuses on participants who have lung (pulmonary) lesions and whose prior standard chemotherapy did not work, to see if the biomarker-driven approach can improve outcomes.
Shanghai, Shanghai MunicipalityAges 8–65 - NCT07089992RecruitingPhase 2
Pembrolizumab for ultra-rare sarcoma types
This trial tests whether pembrolizumab, an immunotherapy that helps your immune system attack cancer cells, can shrink or slow growth in several ultra-rare sarcoma types that have come back or spread. It may be an option if your previous treatments have stopped working.
Basking Ridge, New JerseyAges 18 years+ - NCT07049848RecruitingPhase 2
Study of atezolizumab with chemo and radiation for high-risk sarcoma
This trial tests a combination of immunotherapy (atezolizumab), chemotherapy (doxorubicin), and radiation before and after surgery for people with high-risk soft tissue sarcoma in the arm, leg, or trunk. The goal is to see if this approach can improve outcomes.
Houston, TexasAges 18 years+ - NCT07028086RecruitingPhase 2
VAM for secondary or extramedullary AML
This trial tests a combination of three drugs (called VAM) in people whose acute myeloid leukemia (AML) is either secondary (came from another blood disorder), therapy-related (caused by previous cancer treatment), or has spread outside the bone marrow (extramedullary disease). It is for patients who have not yet received any treatment for their AML.
ShanghaiAges 18–65 - NCT05357768Recruiting
Research study of rare round cell sarcoma biology and outcomes
This study collects information and archived tumor samples from people with undifferentiated round cell sarcoma to better understand the disease. It may help future diagnoses and treatments by linking lab findings in tumor tissue to clinical outcomes.
Bologna, BOAges Any age - NCT06827717RecruitingPhase 2
Liposomal irinotecan combo for advanced Ewing sarcoma
This trial tests a combination of three drugs (liposomal irinotecan, temozolomide, and fluzoparib) for people with Ewing sarcoma that has spread or come back after first treatment. The goal is to see if this combination can help shrink tumors or slow the disease.
Guangzhou, GuangdongAges 18–75 - NCT07014137RecruitingPhase 2
A study of an oral pill for angiogenic sarcomas
This trial tests an oral medication (ABSK043) that may help your immune system fight certain rare sarcomas. It is for people with intimal sarcoma, head and neck angiosarcoma, or epithelioid hemangioendothelioma that has spread or cannot be removed by surgery.
Toronto, OntarioAges 18 years+ - NCT07007273RecruitingPhase 2
Pembrolizumab for advanced skin sarcomas (not angiosarcoma)
This trial is testing a drug called pembrolizumab (Keytruda) for people with advanced soft tissue sarcomas that started in the skin. The goal is to see if this immunotherapy can help shrink or slow the growth of these tumors.
Tampa, FloridaAges 18 years+ - NCT06975293RecruitingPhase 1/Phase 2
STC-15 with toripalimab for advanced cancers and sarcomas
This trial tests a new drug called STC-15, either alone or with another drug (toripalimab), for people with certain advanced cancers or sarcomas that have progressed after prior treatment. The goal is to see if this combination or single drug can help shrink tumors or slow the disease.
San Francisco, CaliforniaAges 18 years+ - NCT06981637RecruitingPhase 2
PLD vs. observation for advanced soft tissue sarcoma
This trial tests whether a type of chemotherapy called pegylated liposomal doxorubicin (PLD) can help keep advanced soft tissue sarcoma from growing after successful first treatment with standard anthracycline-based chemo. You may be eligible if you've completed 4-8 cycles of that initial chemo and your disease is controlled (shrank or stable).
Kaohsiung CityAges 18 years+ - NCT06980259Recruiting
Comparing two types of radiation for soft tissue sarcoma
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
Jinan, ShandongAges 18–70 - NCT06968884Enrolling by invitation
Reducing complications after sarcoma surgery
This trial tests a special care plan before, during, and after surgery to lower the risk of problems for people with sarcoma. It compares this new approach to standard care for 300 patients.
Stockholm, Stockholm CountyAges 15 years+ - NCT06962072Recruiting
Outcomes after limb-sparing surgery for soft tissue sarcoma
This study looks at how well patients do after surgery to remove a soft tissue sarcoma from an arm or leg while saving the limb. It helps doctors understand recovery and function after this type of surgery.
AmsterdamAges 18 years+ - NCT06958107Recruiting
Liquid biopsy study for sarcoma patients
This study uses a simple blood test (liquid biopsy) to look for tiny pieces of tumor DNA in people with sarcoma. It may help doctors learn more about the disease and guide treatment decisions, whether you are just diagnosed, being treated, or have finished treatment recently.
Charlotte, North CarolinaAges Any age - NCT06905132RecruitingPhase 2
Short radiation before surgery for soft tissue sarcoma
This study tests a 5-day course of radiation before surgery instead of the usual 5 weeks. It may help people who face challenges like travel or tumor growth that make the longer schedule difficult.
Charleston, South CarolinaAges 18 years+ - NCT06898203Recruiting
Precision imaging for Kaposi sarcoma
This trial uses advanced imaging to better understand Kaposi sarcoma. If you are starting or already receiving treatment, researchers want to see how imaging can help track your cancer.
KisumuAges 18 years+
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Common questions
- Are there clinical trials for sarcoma?
- Yes. Clin2 currently lists 401 recruiting sarcoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sarcoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sarcoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.