Clinical trials
Schizophrenia and Other Psychotic Disorders clinical trials
Below are recruiting schizophrenia and other psychotic disorders clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07360665Recruiting
Exercise program for people with psychosis on injectable meds
This trial tests a personalized exercise program for people with psychosis who take long-acting injectable antipsychotics. The goal is to see if regular physical activity can improve overall health and well-being.
Vila RealAges 18 years+ - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT07455929Recruiting
Yoga group therapy for schizophrenia
This trial tests whether a yoga-based group program can help people with schizophrenia spectrum disorders feel better. It's designed for outpatients who are stable enough to participate in group therapy.
BerlinAges 18–65 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT04323566Enrolling by invitationPhase 2
Rituximab for OCD or psychosis linked to immune inflammation
This trial tests rituximab (an immune system medicine) to see if it can reduce OCD symptoms and/or psychosis when there are signs the immune system may be involved. You may be considered if other standard psychiatric treatments have not helped enough and your illness seems relatively recent with possible inflammation clues.
UppsalaAges 18–55 - NCT06624462Recruiting
Meta Care Clinic for weight and health in severe mental illness
This study tests a special clinic that helps people with schizophrenia or bipolar disorder manage their weight and metabolic health while taking antipsychotic medication. It focuses on improving overall health with practical support.
Glostrup Municipality, Capital RegionAges 18–45 - NCT06872463Recruiting
Karolinska Schizophrenia Project: Brain study for first episode psychosis
This study examines the brain in people having their first episode of psychosis (like hearing voices or strong false beliefs) to understand more about schizophrenia and related conditions. It involves MRI scans and other tests over one year.
StockholmAges 18 years+ - NCT03995121Recruiting
Brain scan study using a PET tracer
This study tests how a special PET scan tracer behaves in your brain. It may help researchers better understand brain activity and improve imaging for future studies.
New Haven, ConnecticutAges 18–85 - NCT06743711Recruiting
Heart fitness in severe mental illness study
This study checks how fit your heart and lungs are if you have a serious mental illness like schizophrenia or bipolar disorder. It aims to see if fitness can help improve health and well-being.
Glostrup MunicipalityAges 18–45 - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT05951660Recruiting
Study sexual side effects in schizophrenia with diabetes
This study looks at how sexual functioning is affected in people with schizophrenia, especially in those who also have diabetes or weight-related risk. It also examines how psychiatric medicines and diabetes/weight factors may be connected, which could help improve care for patients.
SlagelseAges 18 years+ - NCT04432116Recruiting
Virtual reality training for schizophrenia and bipolar symptoms
This study looks at whether virtual reality and time-based training can improve symptoms for people with schizophrenia or bipolar disorder. You may do virtual-reality tasks as part of your care plan while the team tracks changes over time.
StrasbourgAges 18–60 - NCT07671261Recruiting
Brain surgery for schizophrenia guided by electrode mapping
This trial tests whether deep brain stimulation (DBS) guided by SEEG (a way to map brain activity with electrodes) can help treat schizophrenia. It is for people with moderate to severe symptoms who have not improved after trying at least two different antipsychotic medications.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT03649581Recruiting
Brain-scan study in catatonia and hebephrenia with stable schizophrenia
This study measures brain signals during scans to look for patterns linked to two types (subforms) of psychotic disorders. If you have schizophrenia or schizoaffective disorder and your symptoms have been stable, you may be able to help researchers understand these brain markers.
StrasbourgAges 18–65 - NCT04370730Recruiting
Study brain and symptoms in youth with early psychosis
This study looks at how psychosis symptoms and development change over time in children and teens. It may help doctors better understand different patterns of illness and how to support young people with these disorders.
GentillyAges 7–20 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT00762866Enrolling by invitation
Study of mental health traits using genetic and brain measurements
This study collects information about mental health symptoms and body/genetic samples to better understand how different mental health conditions are related. Some people may also have brain scans (PET or MRI) if they can safely complete them.
Nashville, TennesseeAges 16–65 - NCT04113993RecruitingPhase 4
Bazedoxifene study in women with schizophrenia
This trial tests whether bazedoxifene can help women with schizophrenia who are stable on their current medicines. You may be asked to do questionnaires and thinking (cognitive) tests to see if symptoms or brain-related measures change.
Melbourne, VictoriaAges 18–65 - NCT05890183Recruiting
Telehealth exercise and brain training after a first psychosis episode
This trial tests whether a combination of at-home (telehealth) aerobic exercise and computer-based cognitive training can improve thinking and day-to-day function after a first episode of schizophrenia-spectrum illness. It may help by strengthening attention and learning skills after the initial psychotic episode.
Los Angeles, CaliforniaAges 18–45 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT06505564Recruiting
VR avatar therapy for hearing voices
This study tests a virtual reality (VR) therapy where you talk to a computer-generated avatar that represents the main voice you hear. The goal is to help you feel more in control.
BudapestAges 18 years+ - NCT06568081Recruiting
Studying a therapy for paranoia in psychosis
This trial tests a therapy for people with psychosis who also experience paranoia. It aims to see if the therapy works and whether it's cost-effective in routine care.
LondonAges 18 years+
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Common questions
- Are there clinical trials for schizophrenia and other psychotic disorders?
- Yes. Clin2 currently lists 90 recruiting schizophrenia and other psychotic disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia and other psychotic disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia and other psychotic disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.