Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04798131Recruiting
Brain-scan training to reduce medication-resistant voices
This study uses brain scans (MRI) and real-time feedback to help train the brain to reduce frequent, distressing auditory hallucinations (hearing voices) in people with schizophrenia. If you qualify, you may try a structured neurofeedback program while researchers track changes in your symptoms.
LilleAges 18–60 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT05036590Recruiting
Testing a family support program for first-episode psychosis
This study checks whether a structured family intervention helps caregivers support a person with schizophrenia or a first psychotic episode. You may be asked to take part in a step-by-step program and answer questions to see if it works better than usual care.
BronAges 18 years+ - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT05142735Recruiting
NAC for early psychosis risk symptoms
This trial studies whether NAC (a nutrient-like supplement) can reduce symptoms in people who are at high risk for developing psychosis. It may help by testing a safer, non-standard treatment approach for early warning signs.
Toronto, OntarioAges 16–35 - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70 - NCT05329363Recruiting
Early psychoeducation for people with schizophrenia or related disorders
This study tests a structured early educational program (“psychoeducation”) given to inpatients to help them understand their condition and cope. It may help people feel more informed and better supported during treatment.
BloisAges 18–65 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT05491538Recruiting
Work skills training for Veterans living with serious mental illness
This study tests whether a social-skills training program designed for work goals is doable and helpful for Veterans with serious mental illness. It focuses on improving work-related coping and interactions while you receive supported services through the VA.
Minneapolis, MinnesotaAges 18 years+ - NCT05550155Recruiting
TMS treatment to reduce voices in schizophrenia
This trial studies whether repeated noninvasive brain stimulation (TMS) can help reduce ongoing voice-hearing (auditory verbal hallucinations) in people with schizophrenia or schizoaffective disorder. It focuses on whether doing this after medication is already adjusted can improve symptoms and help keep them controlled.
CaenAges 18–65 - NCT05648591RecruitingPhase 4
Iloperidone study for teens with schizophrenia or bipolar I
This Phase 4 study checks how safe and well-tolerated iloperidone is when used in a typical, open-label way for teenagers. It may help doctors better understand side effects and safety in teens with schizophrenia or bipolar I disorder.
Little Rock, ArkansasAges 12–17 - NCT05698589Recruiting
Therapy program to reduce self-stigma in mental health
This study looks at how a program may help people with long-term mental health conditions feel less shame about their diagnosis (self-stigma). It is meant for adults who are stable enough to participate and who speak French.
BordeauxAges 18 years+ - NCT05763966Recruiting
Uppsala study of psychosis risk and early psychosis
This study follows people with early psychosis, or a high risk of developing psychosis, to better understand brain and symptom changes over time. It may help future prevention or treatment by comparing brain/clinical measurements between people who are at risk, recently affected, and healthy controls.
UppsalaAges 18–40 - NCT05783063Recruiting
TBS treatment for weight gain from antipsychotics
This trial tests a brain-stimulation treatment (TBS) to help reduce increased appetite and weight gain that can happen with antipsychotic medicines. It may be an option if you have schizophrenia and have gained weight after starting antipsychotics, and if you can safely have TBS and MRI exams.
Changsha, HunanAges 18–40 - NCT05805397Recruiting
Motivation skills training for schizophrenia or schizoaffective disorder
This study tests whether “Motivation Skills Training” can help people with schizophrenia or schizoaffective disorder. It’s for people who are stable on treatment and can participate in English-speaking sessions.
New York, New YorkAges 18–65 - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT05945277Recruiting
Peer support after a recent hospital stay
This trial tests a “critical time intervention” approach with peer support for people with a psychotic disorder soon after leaving psychiatric inpatient care. It may help by providing practical support during a high-risk period for relapse and distress.
LisbonAges 18–65 - NCT05945602Recruiting
Using brain signals to guide cognitive rehab in psychosis
This study looks at brain-wave or related “brain signal” measurements to better guide cognitive rehabilitation (thinking and memory skills). It may help people with long-term psychotic disorders, and it also may include healthy comparison volunteers to understand the signals.
San Diego, CaliforniaAges 18–75 - NCT05962216Recruiting
Real-world check of Rexulti for schizophrenia and depression
This study looks at how well brexpiprazole (Rexulti) works in everyday treatment, and how people feel and function over time. You may be eligible if you’re newly started on Rexulti and have a qualifying mental health diagnosis.
Hong KongAges 18–65 - NCT05973110Recruiting
Virtual reality training to improve thinking in psychosis
This trial tests whether a virtual reality program can help people living with psychosis improve thinking and daily functioning. It may help if your symptoms are currently stable and you can safely use the VR equipment.
Ottawa, OntarioAges 18–60 - NCT05982158Recruiting
Talking to an Avatar vs. Talk Therapy for Hearing Voices
This trial compares a new therapy where you talk to a computer avatar that represents the voice you hear, with standard cognitive behavioral therapy (CBT) to help reduce the distress from hearing voices. You must have been hearing voices for at least a year, and they should be upsetting or negative.
Hawthorn, VictoriaAges 18 years+
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 317 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.