Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 306 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06692530Recruiting
Virtual reality study for paranoid delusions in asylum seekers
This study uses virtual reality to help understand and treat paranoid delusions in asylum seekers who have a psychotic disorder. It may help improve care for people with similar experiences.
Balkbrug, OverijsselAges 18 years+ - NCT07230652RecruitingPhase 1
Safety study of LY03020 for healthy volunteers and people with schizophrenia
This study tests the safety of a new medication called LY03020. It is for healthy volunteers and for people with stable schizophrenia. The study aims to see how well the body handles the drug and what side effects might occur.
BeijingAges 18–60 - NCT07234851Enrolling by invitation
Brain tissue study of synaptic loss in mental and brain diseases
This study looks at how brain connections break down in people with psychiatric disorders (like schizophrenia, depression, or bipolar disorder) or neurodegenerative diseases (like Alzheimer's or frontotemporal dementia). It uses donated brain tissue after death to understand why symptoms occur.
BarcelonaAges 40 years+ - NCT07221877RecruitingPhase 4
Study of KarXT for urological safety in schizophrenia
This study tests a new medicine (KarXT) for schizophrenia, focusing on how it affects urological (bladder and urinary) safety. You'll stop your current antipsychotic and take the study drug to see if it works well and is safe for your urinary system.
Little Rock, ArkansasAges 18–65 - NCT07217652Recruiting
Brain study on mental flexibility
This study uses MRI scans to understand how a part of the brain called the mediodorsal thalamus helps you switch between tasks and adapt to new situations. It aims to learn more about cognitive flexibility in healthy adults.
Iowa City, IowaAges 18–35 - NCT06542640Recruiting
Understanding brain changes in youth at risk for psychosis
This research study looks at how the brain changes in young people who are at high risk for developing psychosis. It aims to find better ways to predict and prevent psychosis by using brain imaging and thinking tests.
Shanghai, Shanghai MunicipalityAges 15–35 - NCT07185815RecruitingPhase 1/Phase 2
Study of a long-acting cariprazine shot for mood and schizophrenia
This trial tests a monthly injection of cariprazine (a medication for mental health conditions) in people who could benefit from it. It aims to see if the shot is safe, tolerable, and effective compared to taking pills every day.
AhmedabadAges 18–64 - NCT07146802Recruiting
Personalized thinking training for psychosis
This trial tests a personalized thinking training program for people with schizophrenia to help reduce symptoms like delusions or suspiciousness. It might be a good fit if you have had some of these symptoms recently and are stable on your current treatment.
StrasbourgAges 18–65 - NCT07130500Enrolling by invitation
Rewards for sticking with long-acting injections
This study tests whether offering small rewards (like gift cards) can help people stick with a long-acting injection of their medication. It's for people with serious mental health conditions who have had a recent hospital stay or are at high risk of one.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07131137Enrolling by invitation
Online Life Balance Training for Schizophrenia
This study tests a remote training program to help people with schizophrenia improve their daily life balance. It is done entirely online, so you can join from home.
IstanbulAges 18–65 - NCT07119268Recruiting
Sleep quality study for college students
This study tests whether a sleep program can help college students who have trouble sleeping. You may qualify if you have poor sleep and some unusual experiences, but have never been diagnosed with a psychotic disorder.
Indianapolis, IndianaAges 18–65 - NCT01980147Recruiting
Skills for Wellness program for youth coping with mental health risks
This trial tests a structured skills program to help children and teens (ages 9–21) cope with early mental health warning signs such as anxiety, mood swings, or unusual thoughts. It may help participants build practical coping tools and well-being.
Halifax, Nova ScotiaAges 9–21 - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT07098169Recruiting
Testing a program to improve self-awareness for schizophrenia
This trial tests a program called iTEST that helps people with schizophrenia or schizoaffective disorder improve how accurately they understand their own thoughts. The program combines device use with feedback from a clinician or loved one to support better self-awareness.
San Diego, CaliforniaAges 18–65 - NCT07101094Recruiting
Study on satisfaction with a new schizophrenia treatment
This study tracks how satisfied people with schizophrenia are with a new combination medicine called xanomeline and trospium chloride (XT). It aims to understand real-world experiences and benefits of this treatment.
Orange, CaliforniaAges 18 years+ - NCT07105111RecruitingPhase 4
Valbenazine for tardive dyskinesia after other treatment
This study tests if valbenazine helps adults with tardive dyskinesia whose symptoms continue even after taking or stopping another similar medication. Tardive dyskinesia involves uncontrollable movements from long-term use of certain mental health drugs.
Bryant, ArkansasAges 18 years+ - NCT07091344Recruiting
VR-based therapy for voice hearing in schizophrenia
This study tests whether a virtual reality therapy that lets you talk to an avatar of the voice you hear can help reduce distress and improve thinking skills. It's for people with schizophrenia who hear voices regularly and are on stable medication.
Barcelona, CataloniaAges 18 years+ - NCT06978803Recruiting
Speech and brain study for early psychosis
This study looks at how people with early psychosis (within the first 5 years of treatment) talk during conversations. Researchers hope to learn more about speech patterns and brain activity related to psychosis.
Montreal, QuebecAges 18–60 - NCT07061288RecruitingPhase 1
Testing a new injectable medicine for schizophrenia
This trial tests a new injectable form of KarXT for schizophrenia. It aims to see if the medicine is safe, tolerable, and how it works in the body.
Los Alamitos, CaliforniaAges 18–55 - NCT07058389Recruiting
Exercise in green spaces for schizophrenia symptoms
This study tests whether combining physical activity with being in green outdoor spaces can reduce the tough symptoms of schizophrenia, like feeling flat or unmotivated. It's designed for people whose negative symptoms are not going away.
Saint-Etienne, FranceAges 18–55 - NCT07003529Recruiting
Can brain scans help understand auditory hallucinations?
This study uses brain scans (MRI) to look at a part of the brain called the inferior colliculi in people with schizophrenia who hear voices. The goal is to learn more about why auditory hallucinations happen, which could lead to better treatments in the future.
NîmesAges 18–60 - NCT07006935Recruiting
Clubhouse program effects on recovery and brain health
This study looks at how Clubhouse programs (a type of community-based support) affect thinking and brain health in people with schizophrenia or related conditions. It compares Clubhouse participation to usual care. If eligible, you would complete thinking tests and possibly an MRI brain scan.
Cleveland, OhioAges 18–50 - NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT06978881Enrolling by invitation
Brain activity study for stable schizophrenia
This study uses a brain scan called magnetoencephalography (MEG) to understand brain activity in people with schizophrenia. It may help researchers learn more about the condition and could lead to better treatments.
Montreal, QuebecAges 18–50
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 306 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.