Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07369154RecruitingPhase 3
Safety of a long-term schizophrenia treatment
This study tests the long-term safety of an investigational medication for schizophrenia over one year. It may be an option if you are currently stable on your antipsychotic medication.
Chandler, ArizonaAges 18–65 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT07263022RecruitingPhase 3
Cognitive Training for Early Psychosis Study
This study tests whether a cognitive training program can help young adults with recent psychosis improve their thinking and memory skills. It involves brain scans and cognitive exercises.
Minneapolis, MinnesotaAges 18–35 - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT07713849Recruiting
Transition care for recent psychosis
This study tests a program to help people recently diagnosed with psychosis (within the last two years) transition from hospital to community care. If you have a psychotic disorder and a caregiver involved in your discharge planning, this could help you.
Chicago, IllinoisAges 18–40 - NCT06058702RecruitingPhase 1
Genetics of cannabis use disorder and response
This study looks at how genes affect cannabis use disorder and how people respond to cannabis. It may help explain why some people develop problems with cannabis while others do not.
West Haven, ConnecticutAges 21–60 - NCT07645443Recruiting
Mindfulness group therapy for young adults with early psychosis
This study tests whether a mindfulness-based group therapy program helps young adults who have recently experienced their first psychotic episode. You would participate in group sessions alongside your regular treatment to see if mindfulness can improve how you feel.
Mannheim, Baden-WurttembergAges 16–35 - NCT03217110Recruiting
Brain stimulation study for thinking and control
This trial tests whether stimulating the cerebellum (a part of the brain involved in coordination and learning) can improve “cognitive control,” or the ability to focus and manage thoughts. You may be able to join if you have a diagnosis they are specifically enrolling for and you can safely complete the stimulation and study procedures.
Iowa City, IowaAges 18–90 - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT03649581Recruiting
Brain-scan study in catatonia and hebephrenia with stable schizophrenia
This study measures brain signals during scans to look for patterns linked to two types (subforms) of psychotic disorders. If you have schizophrenia or schizoaffective disorder and your symptoms have been stable, you may be able to help researchers understand these brain markers.
StrasbourgAges 18–65 - NCT03971487RecruitingPhase 1/Phase 2
Ocrelizumab for psychosis linked to an overactive immune system
This Phase 1/2 study tests ocrelizumab, a medicine that affects parts of the immune system, to see if it can improve psychosis symptoms in people with schizophrenia-spectrum disorders. It’s mainly for younger adults with ongoing psychosis and evidence that the symptoms began early in life, with certain infection/vaccine safety requirements.
Houston, TexasAges 18–35 - NCT03995121Recruiting
Brain scan study using a PET tracer
This study tests how a special PET scan tracer behaves in your brain. It may help researchers better understand brain activity and improve imaging for future studies.
New Haven, ConnecticutAges 18–85 - NCT04038840RecruitingPhase 1
Brain PET-MR imaging to study schizophrenia connections
This early (Phase 1) study uses a special brain scan to look at synapses—the contact points between brain cells—in people with schizophrenia-related conditions. It helps researchers understand brain activity and connection patterns, which may guide future tests or treatments.
Palo Alto, CaliforniaAges 18–65 - NCT04237155Recruiting
French memory and attention task for schizophrenia or controls
This study tests how people with schizophrenia and healthy volunteers track sources of information using a French computer task. It may help researchers better understand memory and thinking differences that could guide future support and treatments.
BronAges 18–45 - NCT04278339Recruiting
Brain and behavior study of empathy in schizophrenia
This study looks at brain signals and behavioral measures to understand empathy-related processes in people with schizophrenia or schizoaffective disorder. It may help researchers better understand what’s happening in the brain and how it relates to feelings and social understanding.
NiceAges 18–60 - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT04300946Recruiting
Brain stimulation study using TMS to test time prediction in healthy adults
This study uses a non-invasive brain stimulation method called TMS and brain imaging to understand how the cerebellum affects time prediction. It is for healthy adults and helps researchers learn how brain timing systems work.
StrasbourgAges 18–60 - NCT04368039Recruiting
Breathing regular air pressure oxygen for first-time psychosis
This trial tests whether breathing oxygen (not high-pressure) can improve symptoms in people experiencing a first episode of psychosis. It may help reduce symptoms by changing oxygen delivery to the brain early in the illness.
Columbus, OhioAges 15–35 - NCT04370730Recruiting
Study brain and symptoms in youth with early psychosis
This study looks at how psychosis symptoms and development change over time in children and teens. It may help doctors better understand different patterns of illness and how to support young people with these disorders.
GentillyAges 7–20 - NCT04414215Recruiting
Emotion-focused brain training for schizophrenia or schizoaffective disorder
This study tests a structured cognitive (thinking/skill) training program aimed at improving how people manage emotions. It may help by teaching emotion regulation skills alongside existing care.
Athens, GeorgiaAges 18–60 - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT04580134RecruitingPhase 4
Clozapine study for people with a specific schizophrenia or bipolar type
This trial tests whether clozapine works better for people whose illness fits a specific “biotype-1” pattern. It may help reduce ongoing symptoms, but it also requires close safety monitoring.
Hartford, ConnecticutAges 18–60 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT04730518Recruiting
Group yoga program for people with schizophrenia-spectrum disorders
This trial studies whether a structured group yoga program can help people who are currently receiving care for schizophrenia-spectrum disorders. It focuses on patients with low-to-moderate current psychosis and aims to add a supportive therapy alongside usual treatment.
Steglitz, State of BerlinAges 18–90
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 317 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.