Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07557381Recruiting
Game-Based Brain Training for Schizophrenia
This study tests whether playing games on a smartphone or tablet can help improve memory, attention, and thinking skills in people with schizophrenia. Researchers will track how the game-based training affects cognitive abilities over time.
ShanghaiAges 18–45 - NCT07559084Recruiting
Brain Stimulation for Schizophrenia Negative Symptoms
This trial tests a newer form of brain stimulation called multi-target TMS (transcranial magnetic stimulation) to help reduce negative symptoms of schizophrenia—like reduced emotion, motivation, and speech—in people whose symptoms aren't fully controlled by medication alone.
Shanghai, Shanghai MunicipalityAges 16–45 - NCT07615426RecruitingPhase 1
Testing aticaprant with antipsychotic medication for schizophrenia
This study tests whether a new medication called aticaprant is safe and well-tolerated when added to your current antipsychotic medication for schizophrenia. The goal is to see if it could help improve symptoms without causing serious side effects.
Garden Grove, CaliforniaAges 18–55 - NCT07671261Recruiting
Brain surgery for schizophrenia guided by electrode mapping
This trial tests whether deep brain stimulation (DBS) guided by SEEG (a way to map brain activity with electrodes) can help treat schizophrenia. It is for people with moderate to severe symptoms who have not improved after trying at least two different antipsychotic medications.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07273175Enrolling by invitation
Can brain stimulation improve thinking in schizophrenia?
This study tests if a safe, non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve cognitive functions like memory and attention in people with schizophrenia. If you are between 18 and 65, have a schizophrenia diagnosis, and are mentally stable, you may be eligible.
Lodz, Łódź VoivodeshipAges 18–65 - NCT07225712RecruitingPhase 3
Long-term study of an experimental drug for stable schizophrenia
This trial tests a new medication called SEP-363856 over a long period for people with schizophrenia who are currently stable. It looks at how well the drug works and its safety over time.
FukuokaAges 18 years+ - NCT07173192Enrolling by invitation
Empowerment program for schizophrenia caregivers
This trial tests a program designed to support relatives who care for someone with schizophrenia. It aims to help caregivers feel more confident and capable.
Istanbul, CevizlibağAges 18–65 - NCT07162467Enrolling by invitation
Exploring metabolism and thinking in schizophrenia
This trial looks at how a natural chemical pathway in the body might relate to thinking problems in people with schizophrenia. It compares healthy volunteers to people with schizophrenia to find biological clues.
TianjinAges 18–55 - NCT05165316Enrolling by invitation
Long-acting antipsychotic options for schizophrenia
This study looks at long-acting (extended-release) antipsychotic medicine options in people with schizophrenia, compared with regular tablets. You may be able to join if you were already part of a related earlier study or its real-world follow-up.
Ramat GanAges 18 years+ - NCT07146802Recruiting
Personalized thinking training for psychosis
This trial tests a personalized thinking training program for people with schizophrenia to help reduce symptoms like delusions or suspiciousness. It might be a good fit if you have had some of these symptoms recently and are stable on your current treatment.
StrasbourgAges 18–65 - NCT06817980Recruiting
Sense of self and physical activity study
This study looks at how physical activity affects your sense of self in people with schizophrenia, borderline personality disorder, or inner ear disorders. It involves vision tests, exercise, and questionnaires.
StrasbourgAges 18–60 - NCT06898879Recruiting
Working together to improve mental health care for veterans
This study is for veterans getting mental health support through VA programs. It tests a way to improve teamwork between veterans and their care teams to make the care better.
San Diego, CaliforniaAges 18 years+ - NCT07101094Recruiting
Study on satisfaction with a new schizophrenia treatment
This study tracks how satisfied people with schizophrenia are with a new combination medicine called xanomeline and trospium chloride (XT). It aims to understand real-world experiences and benefits of this treatment.
Costa Mesa, CaliforniaAges 18 years+ - NCT07379827Recruiting
A study on switching to KarXT for schizophrenia
This trial looks at how well KarXT works and what side effects it might have when people with schizophrenia switch to it from their current antipsychotic medication. It may be an option for those who have started KarXT recently or who plan to switch from their current treatment.
Bryant, ArkansasAges 18 years+ - NCT07006935Recruiting
Clubhouse program effects on recovery and brain health
This study looks at how Clubhouse programs (a type of community-based support) affect thinking and brain health in people with schizophrenia or related conditions. It compares Clubhouse participation to usual care. If eligible, you would complete thinking tests and possibly an MRI brain scan.
Cleveland, OhioAges 18–50 - NCT04940663RecruitingTeam says not enrolling
Study brain and feelings in loneliness and social isolation
This study looks at how the brain and behavior relate to loneliness and feeling socially isolated in people with serious mental health conditions. It may help researchers understand what drives loneliness and how it could be addressed in the future.
Charlestown, MassachusettsAges 18–55 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT06562504Recruiting
Study of temporal memory in people with schizophrenia
This study looks at how people with schizophrenia process time-related memories. Researchers will test your memory using tasks on a computer to better understand how the brain works.
Lanzhou, GansuAges 18–50 - NCT06127004Recruiting
Metacognitive training for negative symptoms
This study tests a training program designed to help people with schizophrenia or related conditions better manage challenging thoughts and feelings. It may be a good fit if you have trouble with motivation, social withdrawal, or low energy (negative symptoms).
Multiple LocationsAges 18 years+ - NCT04004364Recruiting
Research study for people enrolled in a schizophrenia care program
This is an early-stage research study for people who are already enrolled in a specific schizophrenia care program. It aims to improve outcomes by testing practice changes within that program.
Lauderdale Lakes, FloridaAges 15–40 - NCT05669742RecruitingPhase 3
Empagliflozin plus olanzapine to reduce metabolic side effects
This trial tests whether adding empagliflozin to standard olanzapine treatment can improve metabolic problems (like blood sugar and cholesterol changes) that can happen with olanzapine in people with schizophrenia. If you qualify, you would be closely monitored for benefits and side effects.
TantaAges 18–65 - NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia
This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.
Buffalo, New YorkAges 21–50 - NCT06969755RecruitingPhase 4
Brain scans and genetics to guide early schizophrenia treatment
This study tests whether using brain scans and genetic tests can help choose the best treatment for people early in their schizophrenia. It will check if these biomarkers can predict who will respond better to medication.
Birmingham, AlabamaAges 18–35 - NCT07534475Recruiting
Tourniquet Type for Monitoring Brain Activity During ECT
This study compares two types of arm tourniquets (blood-pressure cuffs) used during electroconvulsive therapy (ECT) to help doctors monitor seizure activity more accurately. ECT is a treatment for severe depression and other psychiatric conditions, and tourniquets help track how well the treatment is working.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 317 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.