Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 306 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT07424404RecruitingPhase 3
Long-term safety study of a medication for psychiatric disorders in children and teens
This study tests a combination medicine (xanomeline and trospium chloride) to see if it is safe and tolerable over a longer period for children and adolescents with psychiatric disorders, especially those with autism-related irritability. It may help families understand if this treatment can be used beyond the initial study period.
Dothan, AlabamaAges 5–17 - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT07853807Recruiting
Thinking and memory study for adults with schizophrenia and healthy volunteers
This study uses computer tasks to learn how people with schizophrenia think, pay attention, and remember. It may help improve future tests and treatments for schizophrenia. Healthy volunteers are also needed to compare results.
Irvine, CaliforniaAges 18–59 - NCT06197048Recruiting
Nutrition counseling for schizophrenia or bipolar disorder
This study tests whether nutritional counseling can improve body measurements and health markers in people with schizophrenia, psychosis, or bipolar disorder. It may help you manage weight and overall health.
Drammen, AkershusAges 18 years+ - NCT06127004Recruiting
Metacognitive training for negative symptoms
This study tests a training program designed to help people with schizophrenia or related conditions better manage challenging thoughts and feelings. It may be a good fit if you have trouble with motivation, social withdrawal, or low energy (negative symptoms).
Multiple LocationsAges 18 years+ - NCT07856368Recruiting
Magnetic brain stimulation for persistent voices
This study tests a non-invasive brain stimulation treatment called transcranial magnetic stimulation (TMS) to reduce persistent auditory hallucinations (hearing voices) that haven't improved with antipsychotic medication. It may help people who continue to hear voices despite trying several medications.
ZurichAges 18–65 - NCT05329363Recruiting
Early psychoeducation for people with schizophrenia or related disorders
This study tests a structured early educational program (“psychoeducation”) given to inpatients to help them understand their condition and cope. It may help people feel more informed and better supported during treatment.
BloisAges 18–65 - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT06005766Recruiting
Metacognitive skills training in forensic psychiatric care
This study tests if a specialized training program can help people with psychosis (like schizophrenia) who are in forensic psychiatric care. The training focuses on improving how you think about your own thoughts, which may help you manage symptoms better.
VaasaAges 18 years+ - NCT07834203Recruiting
State representation in early psychosis study
This study looks at how the brain processes information in people with early psychosis compared to healthy controls. It may help improve understanding and treatment of psychosis.
Minneapolis, MinnesotaAges 15–45 - NCT07817069Recruiting
Nitraria retusa tea for weight issues caused by clozapine
This trial tests whether a tea made from the plant Nitraria retusa can help reduce the weight gain and metabolic side effects caused by the medication clozapine. If you take clozapine for schizophrenia and have gained weight, this tea might help you manage that side effect.
SousseAges 18–65 - NCT07741981Recruiting
Biological markers for treatment-resistant psychiatric disorders
This study looks for biological markers in the blood or spinal fluid that might predict how well a new psychiatric treatment will work. If you have a psychiatric condition that hasn't improved with previous treatments, this research could help find better ways to match treatments to individuals in the future.
ParisAges 18 years+ - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT07713849Recruiting
Transition care for recent psychosis
This study tests a program to help people recently diagnosed with psychosis (within the last two years) transition from hospital to community care. If you have a psychotic disorder and a caregiver involved in your discharge planning, this could help you.
Chicago, IllinoisAges 18–40 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT07645443Recruiting
Mindfulness group therapy for young adults with early psychosis
This study tests whether a mindfulness-based group therapy program helps young adults who have recently experienced their first psychotic episode. You would participate in group sessions alongside your regular treatment to see if mindfulness can improve how you feel.
Mannheim, Baden-WurttembergAges 16–35 - NCT07621549Recruiting
Ultrasound Brain Stimulation for Schizophrenia Treatment
This study tests whether focused ultrasound waves directed at the brain can help reduce schizophrenia symptoms. If it works, it could offer a new treatment option for people whose symptoms aren't fully controlled by medication alone.
New Taipei CityAges 18–65 - NCT05982158Recruiting
Talking to an Avatar vs. Talk Therapy for Hearing Voices
This trial compares a new therapy where you talk to a computer avatar that represents the voice you hear, with standard cognitive behavioral therapy (CBT) to help reduce the distress from hearing voices. You must have been hearing voices for at least a year, and they should be upsetting or negative.
Hawthorn, VictoriaAges 18 years+ - NCT07616999Recruiting
Long-term follow-up study of early psychosis treatment
This study follows people who were part of an earlier research trial about medication management during their first psychotic episode. Researchers want to understand how those early treatment choices affected their recovery over the past 20 years.
Hong KongAges 18–65 - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT06729541Recruiting
Precision treatments for common mental disorders
This study is developing more personalized treatments for schizophrenia, depression, or bipolar disorder. It may help find the best treatment approach for your specific situation.
Beijing, Beijing MunicipalityAges 18–65 - NCT04038840RecruitingPhase 1
Brain PET-MR imaging to study schizophrenia connections
This early (Phase 1) study uses a special brain scan to look at synapses—the contact points between brain cells—in people with schizophrenia-related conditions. It helps researchers understand brain activity and connection patterns, which may guide future tests or treatments.
Palo Alto, CaliforniaAges 18–65 - NCT07534475Recruiting
Tourniquet Type for Monitoring Brain Activity During ECT
This study compares two types of arm tourniquets (blood-pressure cuffs) used during electroconvulsive therapy (ECT) to help doctors monitor seizure activity more accurately. ECT is a treatment for severe depression and other psychiatric conditions, and tourniquets help track how well the treatment is working.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 306 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.