Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07122895RecruitingPhase 2
NMDA enhancer for negative symptoms in schizophrenia
This study tests whether a medication that boosts brain NMDA receptors can improve negative symptoms in schizophrenia, and looks at differences between men and women. It is for people with stable schizophrenia who still have mostly flat mood or low motivation.
TaichungAges 20–65 - NCT07139171Recruiting
Plasma exosome role in thinking problems in first-episode schizophrenia
This study looks at tiny particles called exosomes in your blood and how small molecules inside them called microRNAs may affect thinking and memory in people with a first episode of schizophrenia. If you join, your blood will be used to help find new ways to understand and treat cognitive symptoms.
TianjinAges 18–65 - NCT07144592Recruiting
Solutions-focused therapy for schizophrenia adjustment
This study tests a talking therapy approach that focuses on solutions to help people with schizophrenia adjust better to daily life and stick with their treatment. It is offered through a Community Mental Health Center.
MuşAges 18–65 - NCT07145918RecruitingPhase 2
Study of an oral schizophrenia drug for adults
This trial tests an experimental oral drug (emraclidine) to see if it helps symptoms of schizophrenia and how it moves through the body. It looks at two groups of participants: those with stable symptoms and those having an acute flare-up.
Little Rock, ArkansasAges 18–65 - NCT07176468Recruiting
Personalized brain stimulation for schizophrenia in real-world settings
This study tests a personalized form of brain stimulation called iTBS for people with schizophrenia. It aims to see if it works in everyday clinical settings.
Hefei, AnhuiAges 18–60 - NCT07191483RecruitingPhase 2
Study of KYN-5356 for cognitive problems in schizophrenia
This trial tests an investigational drug, KYN-5356, to see if it can improve thinking and memory problems in adults with schizophrenia. You may join if your schizophrenia is stable and you take only one antipsychotic medication.
Little Rock, ArkansasAges 18–55 - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT07227818RecruitingPhase 3
Testing NBI-1117568 to prevent schizophrenia relapse
This trial tests a new medicine, NBI-1117568, to see if it can help prevent a relapse of schizophrenia symptoms. It is for adults who have been stable on other antipsychotics and want to avoid returning to the hospital for a psychiatric stay.
Garden Grove, CaliforniaAges 18–65 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT07680959Enrolling by invitation
Brain stimulation for negative symptoms of schizophrenia
This trial tests combining two types of non-invasive brain stimulation (HD-tDCS and iTBS) to help with negative symptoms of schizophrenia, such as lack of motivation or social withdrawal. The goal is to see if this combination can improve these symptoms that are often hard to treat with medication alone.
TaipeiAges 18–65 - NCT07309172Recruiting
KetoBrain: Brain Energy in Schizophrenia
This study looks at how your brain uses energy if you have early schizophrenia. You will have an MRI scan and possibly receive a special diet (ketogenic) to see if it helps your brain work better.
AarhusAges 18–35 - NCT07344948RecruitingEarly Phase 1
Testing NTX-253 in healthy people and those with stable schizophrenia
This trial is testing a new medicine, NTX-253, to see how safe it is and how the body processes it. It is for healthy adults and adults with schizophrenia whose symptoms are stable on their current treatment.
Los Alamitos, CaliforniaAges 18–55 - NCT07363577RecruitingPhase 3
Testing LB-102 for adults with acute schizophrenia
This trial tests a new medication called LB-102 for people with acute (sudden worsening of) schizophrenia. It aims to see if the drug helps reduce symptoms like hallucinations or disorganized thinking.
Bentonville, ArkansasAges 18–65 - NCT01392885Recruiting
Brain health and exercise program for schizophrenia
This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.
Vancouver, British ColumbiaAges 19–45 - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT02455193Recruiting
Exercise study for people with schizophrenia
This study looks at how exercise affects brain function in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can improve brain-related outcomes alongside standard treatment.
Aurora, ColoradoAges 21–70 - NCT02640911Recruiting
Long-term study of certain antipsychines in schizophrenia
This is an observational (non-intervention) study that follows adults with schizophrenia who are taking specific “atypical” antipsychotic medicines long-term. Researchers want to learn about patients’ experiences and outcomes while on these treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07419321Recruiting
Social isolation and aging in schizophrenia study
This study looks at how social isolation affects aging in people with schizophrenia. It may help researchers understand more about the health and well-being of older adults with this condition.
Hartford, ConnecticutAges 40–70 - NCT07428460Recruiting
Speedy brain stimulation for persistent negative symptoms in schizophrenia
This trial tests if a new, faster form of brain stimulation called accelerated neuromodulation therapy can help reduce negative symptoms (like loss of motivation or social withdrawal) in people with schizophrenia. It aims to see if this treatment can improve daily functioning and quality of life.
Montreal, QuebecAges 18–65 - NCT07434479Recruiting
Virtual reality mindfulness for aggression in schizophrenia
This study tests whether a virtual reality mindfulness program can help people with schizophrenia who have problems with impulsive aggression. You would use a VR headset for relaxation exercises and answer questions about your mood and behavior.
New York, New YorkAges 18–64 - NCT07455929Recruiting
Yoga group therapy for schizophrenia
This trial tests whether a yoga-based group program can help people with schizophrenia spectrum disorders feel better. It's designed for outpatients who are stable enough to participate in group therapy.
BerlinAges 18–65 - NCT06674694RecruitingPhase 1
Testing brexpiprazole long-acting shot for schizophrenia
This study tests an injectable form of brexpiprazole that stays in the body for a long time. It aims to see if the shot is safe and tolerable for healthy volunteers and people with schizophrenia, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–65 - NCT07493551Recruiting
Bioequivalence study of a long-acting injection for schizophrenia
This trial tests whether a new version of an extended-release injection is as effective as the original in people with schizophrenia. The study helps ensure patients have access to a reliable treatment option.
Beijing, Beijing MunicipalityAges 18–65 - NCT07557368Recruiting
Gamified games to help with thinking and recovery in schizophrenia
This study tests whether playing structured games on a phone or tablet can help people with schizophrenia improve their thinking skills, memory, and social confidence while in the hospital. The games are designed to be engaging and therapeutic.
ShanghaiAges 18–45
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 317 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.