Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07051694Recruiting
Ear nerve stimulation for sepsis patients in the ICU
This trial tests a non-invasive ear stimulation device (taVNS) as an extra treatment for sepsis in the ICU. It may help reduce inflammation and improve recovery.
ChongqingAges 18–80 - NCT07040202Recruiting
Immune system study for dengue, flu, and sepsis patients
This study looks at how the immune system responds to dengue, flu, and sepsis. It may help doctors understand these illnesses better and improve future treatments.
Kampong SpeuAges 2 years+ - NCT07022041Recruiting
Sepsis and survival in heart patients
This study looks at how sepsis and other infections affect survival in hospitalized heart patients. It is designed for people who are being treated for a heart condition and either have no infection or have a specific type of infection or heart inflammation.
CosenzaAges 18 years+ - NCT07009665Recruiting
Fluid management in sepsis patients at the emergency department
This study tests a personalized approach to giving fluids to patients with sepsis, a serious infection that can cause low blood pressure. The goal is to see if individualized fluid resuscitation improves outcomes compared to standard care.
Groningen, Provincie GroningenAges 18 years+ - NCT06184659RecruitingPhase 4
Comparing two antibiotics for sepsis in critical illness
This trial compares two common antibiotics, meropenem and piperacillin/tazobactam, to see which works better for adults with sepsis who are critically ill. It aims to help doctors choose the best treatment for serious infections.
Copenhagen, København ØAges 18 years+ - NCT06854640RecruitingPhase 1
A study of a new medicine for sepsis-related blood clotting problems
This study tests a new medicine called BAY 3389934 to see if it's safe and what dose works best for people with sepsis and blood clotting issues. The goal is to improve blood clotting and help you recover from the infection.
Aurora, ColoradoAges 18–85 - NCT06845332Recruiting
Best treatment choices for newborns with suspected early infection
This trial is testing ways to make the best treatment decisions for newborns who may have an early infection (sepsis). It focuses on babies born at 34 weeks or later and within their first three days of life.
AlkmaarAges Up to 3 days - NCT06287684Recruiting
Sepsis treatment study based on genetic subtypes
This study looks at how different genetic types of sepsis affect treatment. It aims to find better therapies for your specific sepsis subtype.
MsidaAges 18 years+ - NCT06731088Enrolling by invitationPhase 4
Sedation with remazolam and remifentanil for sepsis patients
This study tests a combination of two sedative drugs (remazolam besylate and remifentanil) for calming patients with sepsis who are on a ventilator in the ICU. The goal is to see if this approach improves recovery compared to standard care.
Ningbo, ZhejiangAges 18–75 - NCT04910464RecruitingPhase 3
Tranexamic acid trial for adults with sepsis in ICU
This trial studies whether early tranexamic acid (a medicine that can reduce bleeding) can change the body’s inflammatory response in people with sepsis. If it works, it may help improve outcomes for certain ICU patients—but you must meet specific safety and eligibility checks.
AsyutAges 18–65 - NCT06712641RecruitingPhase 4
Testing aminoglycoside antibiotics for early sepsis
This trial tests a type of antibiotic called aminoglycosides to treat early sepsis (a serious infection). It is for adults in the hospital who are sick enough to need strong antibiotics but not in the worst stage of the illness.
Bergen, BergenAges 18 years+ - NCT06686355RecruitingPhase 2
Yiqilishui formula for sepsis-related heart problems
This trial tests a Chinese herbal formula called Yiqilishui in people with sepsis who have developed heart muscle weakness. It aims to see if the formula can help improve heart function.
BeijingAges 50–85 - NCT06514339RecruitingEarly Phase 1
Shenhuang granules for sepsis treatment
This trial tests if Shenhuang granules, a traditional Chinese medicine, can help treat sepsis (a life-threatening response to infection). It aims to see if it improves outcomes for patients with sepsis.
Hangzhou, ZhejiangAges 18 years+ - NCT05985525Recruiting
Monitoring blood flow in ICU patients with severe infection or shock
This study monitors tiny blood vessels under the tongue using a non-invasive device to see how well blood flows in ICU patients on a breathing machine. Researchers hope to improve care for patients with serious infections or shock.
Winnipeg, ManitobaAges 18 years+ - NCT06562803Recruiting
Cleaning the blood for liver failure with sepsis
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Guangzhou, GuangdongAges 18–70 - NCT06512129Recruiting
Measuring fluid levels in sepsis patients
This study measures fluid levels outside your cells to better understand and manage sepsis. It may help doctors give the right amount of fluids during treatment.
Uppsala, UppsaAges 18 years+ - NCT06381661RecruitingPhase 2
Personalized treatment for sepsis in children and adults
This trial is testing several different treatments to find the best one for each person with sepsis. It looks at specific 'treatable traits' like inflammation, blood clotting problems, or immune system issues to match you with the right therapy. The goal is to improve recovery and survival.
DijonAges 9 months+ - NCT06344819RecruitingPhase 2
Acupuncture for People at High Risk of Sepsis
This study tests whether acupuncture can help people at high risk for sepsis, a serious infection that can lead to organ failure. If you’re 18 or older, have had a sepsis order set put in within the last two days, and are not yet in the ICU, you may be able to join.
Irvine, CaliforniaAges 18 years+ - NCT06319248RecruitingPhase 2
Midodrine to treat sepsis and reduce IV vasopressors
This trial tests if the oral medication midodrine can help wean patients with sepsis off IV vasopressors faster, potentially reducing ICU stays and complications.
Scottsdale, ArizonaAges 18 years+ - NCT06294600RecruitingPhase 3
Clarithromycin to prevent sepsis in pneumonia
This study tests whether the antibiotic clarithromycin can prevent pneumonia from getting worse and turning into sepsis. It is for adults with community-acquired pneumonia who have certain signs of infection in their blood.
Athens, AthensAges 18 years+ - NCT04280497Recruiting
Testing fast ways to tell steroid-resistant sepsis from sensitive
This trial studies a quick set of tests to figure out whether a person with severe infection (sepsis) will respond to corticosteroids like hydrocortisone. The goal is to guide treatment sooner and avoid ineffective care.
Garches, Hauts-de-SeineAges 18 years+ - NCT06219135Recruiting
Testing a new method to find infection germs and best antibiotics
This trial is testing a new method (IDBIORIV) to quickly identify the germs causing sepsis and find the right antibiotic. It aims to help patients with a confirmed bloodstream infection get the most effective treatment faster.
BronAges 1 day+ - NCT06160349Enrolling by invitation
Improving care for new mothers with infection risk
This study asks patients and community experts to share their experiences with infections during pregnancy, delivery, or after birth. Your answers can help hospitals better support mothers and prevent serious illness from infections.
New York, New YorkAges 18 years+ - NCT06148532Enrolling by invitation
Reducing illness from maternal sepsis study
This study looks at medical records of people who gave birth and were later readmitted to the hospital for postpartum care. It aims to find better ways to prevent and treat sepsis, a serious infection, in mothers.
New York, New YorkAges 18 years+
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.