Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02055105Recruiting
Study tests a blood test pattern in children with sepsis
This trial studies how a specific pattern in blood (called “molecular fingerprinting”) changes in children with suspected or developing sepsis. The goal is to help doctors better recognize sepsis early and understand how it progresses, which may improve care.
Phoenix, ArizonaAges 1–18 - NCT05912413Recruiting
Predicting how people recover from sepsis in the ICU
This pilot study looks at whether doctors can sort ICU patients with sepsis into recovery “types” and predict how well they will recover. It may help future care plans for people after sepsis by identifying who needs what kinds of support.
Birmingham, AlabamaAges 18–80 - NCT05882708RecruitingPhase 4
Ivabradine to slow heart rate in sepsis ICU patients
This study tests whether ivabradine (a heart-rate medicine) can improve blood flow and other vital measurements in adults with sepsis in the ICU. It may help by lowering a fast heart rate when blood pressure is already being supported.
Guangzhou, GuangdongAges 18 years+ - NCT05875740Recruiting
Memory T cells and sepsis severity study
This study looks at a type of immune cell called 'memory CD8+ T cells' in patients with sepsis, a life-threatening response to infection. The goal is to see if these cells are linked to how severe the sepsis is and the risk of dying. This may help doctors better predict outcomes for people with sepsis.
Wuhan, HubeiAges 18–60 - NCT05383963Recruiting
Using ICU routine data to diagnose sepsis sooner
This study checks whether information collected routinely in the ICU can help doctors recognize sepsis or septic shock earlier. If it works, it may improve how quickly diagnosis happens and potentially outcomes for patients.
BerlinAges 18 years+ - NCT05616130Recruiting
Study of abnormal blood immune activation after trauma or elective hip surgery
This study looks at how the body’s blood-related immune system “switches on” in unusual ways after a major injury or elective hip repair. The researchers hope this helps them understand who is at risk for complications and why, by measuring changes in your blood around the time of surgery or hospital treatment.
Gainesville, FloridaAges 18–100 - NCT05453695RecruitingPhase 1
IV DNase for ICU sepsis with organ stress
This Phase 1 study tests whether an IV medicine called DNase I can safely help people with sepsis who are having worsening organ function. It’s designed to see if the treatment is tolerated and could improve outcomes for ICU patients with early sepsis.
Hamilton, OntarioAges 18–100 - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Birmingham, AlabamaAges 1 day–17 years - NCT05179499RecruitingPhase 3
Early norepinephrine for low blood pressure in sepsis
This Phase 3 trial tests whether starting a medicine called norepinephrine early can improve outcomes for adults with sepsis (a serious body-wide response to infection) and low blood pressure. You might be considered if you’re very early in hospital care and meet specific blood pressure and lactate tests.
AintreeAges 18 years+ - NCT05110937Recruiting
Testing immune cell changes in sepsis and trauma shock
This study looks at abnormal immune cells (from the bone marrow) in people with sepsis or severe trauma with shock. It aims to understand why the body’s immune response gets out of balance, which could help guide future treatments.
Gainesville, FloridaAges 18–100 - NCT04955210Recruiting
Study of data sharing in children with severe infections
This trial builds a shared medical data system to better understand severe pneumonia and sepsis in children. Your participation helps clinicians and researchers learn from many cases to improve future care.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT03146546Enrolling by invitation
Study of sepsis groups to guide future care
This study looks at different types (“endotypes”) of sepsis in adults to better understand what’s happening in the body and how patients may respond. You might be asked to provide information and samples as the study tries to sort sepsis into meaningful subgroups.
Hershey, PennsylvaniaAges 18 years+ - NCT07556107RecruitingPhase 4
Safety study of two antibiotics for serious hospital infections
This study watches how safely two common antibiotics (vancomycin and a combination called piperacillin/tazobactam) work together in hospitalized patients with serious infections. Researchers want to make sure the combination doesn't harm kidney function.
Worcester, MassachusettsAges 18 years+ - NCT04140578RecruitingPhase 4
Antibiotic prevention for certain liver disease patients
This trial tests whether taking preventive antibiotics can help people with certain liver conditions avoid infections after an endoscopy-related procedure. It may reduce infection risk, but it also requires that you have no signs of infection and haven’t recently taken antibiotics.
TaipeiAges 20–85 - NCT00901602Recruiting
Study of invasive pneumococcal infections in Lebanon
This study collects laboratory samples from patients with invasive pneumococcal infections to learn about the germ and where it spreads. It may help doctors and public health teams track infection patterns and improve prevention and treatment planning.
BeirutAges 1 day+ - NCT06076200Recruiting
How Piperacillin/Tazobactam works in pregnant women and newborns
This study looks at how the antibiotic Piperacillin/Tazobactam moves through the body of pregnant women and their newborns. It may help doctors decide the best dose to prevent infections in babies at risk.
JinanAges 18 years+ - NCT05604846Recruiting
Probiotic drops for very preterm babies in Scandinavia
This trial studies whether giving probiotic supplements to extremely preterm newborns helps improve health outcomes. It’s meant for babies born very early, and the results could help guide safer early nutrition and care.
Solna, Stockholm CountyAges 5 months–6 months - NCT06145841Recruiting
Gene test to guide infection treatment in AIDS
This study is for people with HIV/AIDS who develop severe pneumonia or septic shock. It uses a special genetic test (metagenomic next-generation sequencing) to find the exact germ causing the infection so doctors can choose the right antibiotic.
Guangzhou, GuangdongAges 18–65 - NCT06226441Recruiting
Aminoglycoside antibiotics for sepsis with low kidney function
This study tests how well aminoglycoside antibiotics work in people with sepsis who also have low kidney function. It may help find the best way to treat serious infections in patients with kidney problems.
Larissa, ThessalyAges 18 years+ - NCT07859852Recruiting
Blood test for bloodstream infections
This study tests a new blood test that may find bloodstream infections faster and more accurately than standard methods. It could help doctors start the right treatment sooner.
Orange, CaliforniaAges Any age - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT07831057Recruiting
Temperature control for patients with sepsis
This trial tests whether actively warming a cool, sedated intensive-care patient with sepsis helps recovery. Sepsis is a life-threatening reaction to infection that can make body temperature drop, and this study aims to see if warming can improve outcomes.
Rotterdam, South HollandAges 18 years+ - NCT07821190Recruiting
Blood marker for late infection in preterm babies
This study tests a new blood marker (called MDW) to help doctors quickly spot late-onset sepsis in preterm babies. If it works, it could lead to faster treatment for infections in premature infants.
TantaAges 3 days–4 weeks
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.