Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07320638Enrolling by invitation
TRIM25 study in people with sepsis
This trial looks at a protein called TRIM25 in patients with sepsis (a serious infection). It may help doctors understand the condition better.
ShanghaiAges 18–70 - NCT06845332Recruiting
Best treatment choices for newborns with suspected early infection
This trial is testing ways to make the best treatment decisions for newborns who may have an early infection (sepsis). It focuses on babies born at 34 weeks or later and within their first three days of life.
AlkmaarAges Up to 3 days - NCT06731088Enrolling by invitationPhase 4
Sedation with remazolam and remifentanil for sepsis patients
This study tests a combination of two sedative drugs (remazolam besylate and remifentanil) for calming patients with sepsis who are on a ventilator in the ICU. The goal is to see if this approach improves recovery compared to standard care.
Ningbo, ZhejiangAges 18–75 - NCT06160349Enrolling by invitation
Improving care for new mothers with infection risk
This study asks patients and community experts to share their experiences with infections during pregnancy, delivery, or after birth. Your answers can help hospitals better support mothers and prevent serious illness from infections.
New York, New YorkAges 18 years+ - NCT06148532Enrolling by invitation
Reducing illness from maternal sepsis study
This study looks at medical records of people who gave birth and were later readmitted to the hospital for postpartum care. It aims to find better ways to prevent and treat sepsis, a serious infection, in mothers.
New York, New YorkAges 18 years+ - NCT03146546Enrolling by invitation
Study of sepsis groups to guide future care
This study looks at different types (“endotypes”) of sepsis in adults to better understand what’s happening in the body and how patients may respond. You might be asked to provide information and samples as the study tries to sort sepsis into meaningful subgroups.
Hershey, PennsylvaniaAges 18 years+ - NCT07779720Recruiting
Personalized fluids for emergency sepsis care
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
Murray, UtahAges 18 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT07774962Recruiting
Comparing fingertip refill time and blood oxygen use in septic shock
This study looks at two ways to check blood flow and oxygen use in people with septic shock, a severe infection-related condition. It aims to see if a simple bedside test (fingertip refill) and a blood measure (oxygen extraction ratio) agree, which could help guide treatment.
IstanbulAges 18 years+ - NCT07556107RecruitingPhase 4
Safety study of two antibiotics for serious hospital infections
This study watches how safely two common antibiotics (vancomycin and a combination called piperacillin/tazobactam) work together in hospitalized patients with serious infections. Researchers want to make sure the combination doesn't harm kidney function.
Cooperstown, New YorkAges 18 years+ - NCT06893939RecruitingPhase 2/Phase 3
Feeding approach for very premature babies
This study compares two ways of starting tiny feedings in very premature babies. The goal is to see if a shorter or longer period of very small feedings leads to better growth and fewer feeding problems. If you are okay with your baby receiving donor breast milk when needed, this trial may be a good fit.
Birmingham, AlabamaAges birth–2 years - NCT05575024Recruiting
Monitoring blood pressure and heart rhythm during kidney support in sepsis
This study looks at how stable blood pressure and heart rhythm are in people with sepsis who need continuous kidney filtration. If you qualify, it may help researchers better improve care for critically ill patients receiving this treatment.
SeoulAges 18 years+ - NCT07460349Recruiting
Extended interval gentamicin dosing in newborns
This study looks at spacing out doses of the antibiotic gentamicin for newborns up to 7 days old who need it. The goal is to make sure the dosing schedule works well and is safe for babies.
London, OntarioAges birth–1 week - NCT06527443Recruiting
Arterial stiffness in adults with sepsis
This study measures how stiff your arteries are during sepsis, which may help doctors understand your condition better. You need to be an adult in the ICU with sepsis and be tested within 24 hours.
AsyutAges 18 years+ - NCT07739004Recruiting
Fever in Children: Predictors of Serious Illness
This study looks at children with fever to find early signs that might predict serious illness, helping doctors make better triage decisions in the emergency room.
Kayseri, TalasAges birth–18 years - NCT06853301Recruiting
A faster test to find bloodstream infections
This study tests a new machine learning method to quickly identify bacteria in the blood using special sample bottles. If you are getting blood cultures done already, this may help get results faster.
GrenobleAges 18 years+ - NCT07388628Recruiting
Observing ARTICE® treatment in the ICU
This study is collecting real-world data on ARTICE® treatment for adults in the ICU. It helps doctors understand how this treatment works in daily practice.
MagdeburgAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+ - NCT03720860Recruiting
Study inflammatory signals in sudden kidney injury in ICU
This study looks at substances related to inflammation to better understand sudden kidney problems in people who are very sick in the ICU. It may help improve how kidney injury is predicted and treated after severe illness or major events.
Uppsala, Uppsala CountyAges 18 years+ - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT04033224Recruiting
Blood-filter treatments for ICU patients with kidney and organ failure
This trial tests a specific type of blood-filter treatment in critically ill ICU patients who have acute kidney injury and/or failure of other organs. It aims to see whether these filters can improve care by supporting kidney function and/or calming harmful inflammation.
Empoli, FirenzeAges Any age - NCT04140578RecruitingPhase 4
Antibiotic prevention for certain liver disease patients
This trial tests whether taking preventive antibiotics can help people with certain liver conditions avoid infections after an endoscopy-related procedure. It may reduce infection risk, but it also requires that you have no signs of infection and haven’t recently taken antibiotics.
TaipeiAges 20–85
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 268 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.