Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06446947Recruiting
Blood markers for poor outcomes after sepsis in cancer surgery
This study looks at blood markers (epigenetics) to better understand why some people have a harder time recovering from a severe infection after major cancer surgery. The goal is to find early signs of poor outcomes in men aged 45–75 with post-surgery sepsis.
Marseille, Bouches du RhôneAges 45–75 - NCT06464510RecruitingPhase 3
Treating sepsis with norepinephrine plus early vasopressin
This trial tests whether giving a second medicine called vasopressin early (along with norepinephrine) helps people with sepsis and low blood pressure better than waiting to use vasopressin only if norepinephrine doesn't work. It may improve blood pressure control and reduce the need for strong medicines.
Caxias do Sul, Rio Grande do SulAges 18 years+ - NCT07530146RecruitingPhase 3
Sedation Medications for Older ICU Patients on Breathing Machines
This study compares two sedation medications—propofol alone versus propofol combined with ketamine—in older patients in the ICU who are on breathing machines due to infection or lung problems. The goal is to find which combination is safer and works better for keeping patients calm and comfortable.
CairoAges 65 years+ - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90 - NCT06680180Recruiting
Blood Clot Breakdown in Severe Infection and Injury
This trial studies how well the body's natural clot-busting system works in people with serious infections or major injuries. It may help doctors find better ways to treat these conditions.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06693726RecruitingPhase 4
Early blood pressure medication in the ER
This trial tests a drug called angiotensin II for people in the emergency room who need a specific dose of norepinephrine (a medicine to raise blood pressure) and are also getting antibiotics. The goal is to see if giving angiotensin II early can help stabilize blood pressure.
Iowa City, IowaAges 18–99 - NCT07682766Recruiting
Biomarkers of inflammation and infection in critical care
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
TorinoAges 18 years+ - NCT06749756Recruiting
Vitamins B6, B12 and C for sepsis
This trial tests whether a combination of vitamins B6, B12, and C can help improve blood flow in tiny blood vessels (microcirculation) for people with sepsis. It may help your body recover better from severe infection.
Chengdu, SichuanAges 18–85 - NCT06754696Recruiting
Testing a blood protein in children with and without infection
This study looks at a specific blood protein level in children from birth to age 17. It compares healthy children and those with sepsis to see if the protein changes during infection.
NantesAges Up to 17 years - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT06915974Recruiting
Comparing Blood Tests for Sepsis in Burn ICU Patients
This study is comparing two blood tests (Interleukin 6 and Procalcitonin) to find which is better at detecting sepsis (a serious infection) and predicting the risk of death in burn patients in the ICU. If you have moderate burns and are otherwise healthy, this trial could help improve care for burn victims.
CairoAges 25–60 - NCT07063095RecruitingPhase 3
Testing two antibiotics combined for serious bacterial infections
This study tests whether combining two antibiotics (ceftazidime and fosfomycin) works better than ceftazidime alone for hospitalized adults with serious bacterial infections. If you have a severe infection thought to be caused by Gram-negative bacteria, this trial may offer a new treatment option.
Geneva, Canton of GenevaAges 18 years+ - NCT07067866RecruitingPhase 3
Best way to stop vasopressin in sepsis patients
This trial compares two ways to safely stop the vasopressin medication in people with sepsis who are in the ICU. It aims to find the best approach to wean off this blood pressure support, which could help you recover more smoothly.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07230041Recruiting
Antibiotic removal during kidney therapy in the ICU
This trial studies how much certain antibiotics (meropenem, linezolid, and daptomycin) are removed when you're on a special blood-filtering machine called continuous renal replacement therapy (CRRT) for severe kidney injury. The results could help doctors give the right dose of antibiotics to treat infections effectively.
Milan, ItaliaAges 18 years+ - NCT07425587Recruiting
Symphony IL-6 test for sepsis in the emergency room
This trial checks if a new blood test (Symphony IL-6) can help doctors quickly identify sepsis in patients coming to the emergency room. It may speed up diagnosis and treatment for serious infections.
Gainesville, FloridaAges 22 years+ - NCT07286643Recruiting
Ultrasound-guided sepsis care for patients with cirrhosis
This study tests whether using a special ultrasound of the heart can guide treatment for sepsis-related low blood pressure in patients with cirrhosis. It aims to improve care and outcomes for critically ill patients.
ChandigarhAges 18–65 - NCT07343206Recruiting
Early norepinephrine for sepsis with low blood pressure
This trial tests whether giving a medicine called norepinephrine early and adjusting the dose quickly can help people with sepsis who have very low blood pressure. It is for adults who are diagnosed within the last 3 hours and who have not already received this medicine.
Bangkok Noi, BangkokAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT02936232Recruiting
Registry for severe sepsis and septic shock
This registry collects medical information from adults who have suspected or proven serious infection causing body organ problems. It helps researchers better understand what happens in severe sepsis and septic shock and may guide future care.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07411469Recruiting
Comparing heart monitoring methods in sepsis patients
This study compares two methods to measure fluid responsiveness in patients with sepsis and hypotension: cardiometry (non-invasive heart monitoring) and ultrasound of the IVC vein. The goal is to find a simpler way to guide treatment.
Shibīn al Kawm, MenoufiaAges 18–65 - NCT07419802Recruiting
Study of a special filter for septic shock patients
This trial tests a special blood filter called Oxiris that may help remove toxins and inflammation from the blood in patients with septic shock. It aims to see if this treatment can improve outcomes for people who need kidney replacement therapy.
RigaAges 18 years+ - NCT06904001Enrolling by invitation
Early warning model for sepsis in critically ill patients
This trial is building a tool to predict sepsis, a life-threatening response to infection, in intensive care patients. It may help doctors act faster to prevent complications.
Wenzhou, ZhejiangAges 18–99 - NCT05304728Enrolling by invitation
Hospital sepsis decision support program enrollment study
This study tests a computer system meant to help doctors recognize and manage sepsis (a serious body-wide response to infection) when people come to the emergency department or are admitted to the hospital. If you’re evaluated in a hospital setting for possible sepsis, you may be included to help improve care decisions.
Irvine, CaliforniaAges 18–89
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Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 120 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.