Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07779720Recruiting
Personalized fluids for emergency sepsis care
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
Murray, UtahAges 18 years+ - NCT05575024Recruiting
Monitoring blood pressure and heart rhythm during kidney support in sepsis
This study looks at how stable blood pressure and heart rhythm are in people with sepsis who need continuous kidney filtration. If you qualify, it may help researchers better improve care for critically ill patients receiving this treatment.
SeoulAges 18 years+ - NCT06492044Recruiting
Testing right heart strain to predict fluid response in septic shock
This study tests whether measuring the strain (stretch) of the right upper heart chamber with ultrasound can predict if a patient with septic shock will benefit from more fluids. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AmiensAges 18 years+ - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+ - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT04203979Recruiting
Sepsis care tailored to patients
This study looks at how to better recognize and manage sepsis (a serious body-wide reaction to infection) and tailor care to the individual. You may be eligible if you are newly admitted to the emergency department and your care is handled by a rapid response team for sepsis.
OsloAges 18 years+ - NCT04448951Recruiting
Study of immune response in early sepsis or septic shock
This trial looks at how the immune system behaves in the first day after septic shock begins. It may help researchers find better ways to support the body’s immune balance during sepsis, but you must be enrolled very quickly.
Pilsen, Česká RepublikaAges 18 years+ - NCT04774705Recruiting
Noninvasive vagus nerve stimulation for sepsis in the ICU
This study tests whether a noninvasive device that stimulates the vagus nerve can help adults with sepsis in the intensive care unit. Researchers want to see if adding this treatment improves outcomes compared with standard ICU care.
GarchesAges 18 years+ - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT04920565Recruiting
Hemoperfusion with Polymyxin B for septic shock after heart surgery
This trial studies a blood-filter treatment (hemoperfusion with Polymyxin B) to reduce harmful substances in the blood for people who develop septic shock after heart surgery. It may help by lowering inflammation and improving safety, but it also requires meeting specific signs of severe infection and blood/bleeding conditions.
MoscowAges 18–80 - NCT05225402Recruiting
Testing blood-flow measurements in ICU shock patients
This trial studies how blood flow and organ “perfusion” look in ICU patients who are struggling with infection and low blood pressure. It may help doctors better measure and manage shock by comparing hemodynamic readings during standard treatment.
Hvidovre, CopenhagenAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT05491941Recruiting
Testing ways to improve care for sepsis patients
This trial looks at how to best put proven sepsis care steps into practice in the emergency department. It may help you or other patients receive faster, more consistent treatment for sepsis.
Providence, Rhode IslandAges 18 years+ - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05761522Recruiting
Testing norepinephrine for blood pressure in septic shock
This trial studies how norepinephrine affects the heart and circulation in adults with septic shock whose blood pressure stays low after the first day. It may help doctors better choose and adjust medicines to support blood pressure and organ function.
ReimsAges 18 years+ - NCT06143137Recruiting
Long-term recovery after septic shock treatment
This study checks on people who had septic shock and were in the ReActIF-ICE trial. It looks at how their immune system recovered over time after an experimental therapy.
MagdeburgAges 18–80 - NCT06178822Recruiting
New blood tests to diagnose sepsis in the ER
This study aims to find new ways to quickly diagnose sepsis (a severe response to infection) in patients arriving at the emergency room. If successful, these new tests could help doctors start treatment faster.
Almere Stad, FlevolandAges 18 years+ - NCT06184659RecruitingPhase 4
Comparing two antibiotics for sepsis in critical illness
This trial compares two common antibiotics, meropenem and piperacillin/tazobactam, to see which works better for adults with sepsis who are critically ill. It aims to help doctors choose the best treatment for serious infections.
Copenhagen, København ØAges 18 years+ - NCT06287684Recruiting
Sepsis treatment study based on genetic subtypes
This study looks at how different genetic types of sepsis affect treatment. It aims to find better therapies for your specific sepsis subtype.
MsidaAges 18 years+ - NCT06330610Recruiting
Intermittent tube feeding for organ failure in the ICU
This trial tests if giving tube feeding at certain times of day, instead of continuously, helps people on breathing machines recover from organ failure faster. It is for patients who need a breathing tube and are receiving medicine to support their blood pressure.
Rouen, FranceAges 18 years+ - NCT06370078Recruiting
Albumin 20% vs Standard Fluids for Septic Shock
This trial tests whether giving a concentrated protein solution (albumin 20%) early in septic shock helps better than standard fluids (crystalloids). It's for people who have been in septic shock less than 24 hours and still need blood pressure support.
AsyutAges 18–60
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Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 120 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.