Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06143137Recruiting
Long-term recovery after septic shock treatment
This study checks on people who had septic shock and were in the ReActIF-ICE trial. It looks at how their immune system recovered over time after an experimental therapy.
MagdeburgAges 18–80 - NCT07779720Recruiting
Personalized fluids for emergency sepsis care
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
Murray, UtahAges 18 years+ - NCT04448951Recruiting
Study of immune response in early sepsis or septic shock
This trial looks at how the immune system behaves in the first day after septic shock begins. It may help researchers find better ways to support the body’s immune balance during sepsis, but you must be enrolled very quickly.
Pilsen, Česká RepublikaAges 18 years+ - NCT07706413Recruiting
Plasma exchange for children with severe sepsis
This trial tests whether removing harmful substances from the blood (plasma exchange) can help children with severe infections that cause organ failure or very low blood pressure. If your child is in the hospital with severe sepsis or septic shock and is between 1 month and 18 years old, this treatment might be an option.
Shibīn al Kawm, Menoufia GovernorateAges 1 month–18 years - NCT07682766Recruiting
Biomarkers of inflammation and infection in critical care
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
TorinoAges 18 years+ - NCT06680180Recruiting
Blood Clot Breakdown in Severe Infection and Injury
This trial studies how well the body's natural clot-busting system works in people with serious infections or major injuries. It may help doctors find better ways to treat these conditions.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT04920565Recruiting
Hemoperfusion with Polymyxin B for septic shock after heart surgery
This trial studies a blood-filter treatment (hemoperfusion with Polymyxin B) to reduce harmful substances in the blood for people who develop septic shock after heart surgery. It may help by lowering inflammation and improving safety, but it also requires meeting specific signs of severe infection and blood/bleeding conditions.
MoscowAges 18–80 - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT06749756Recruiting
Vitamins B6, B12 and C for sepsis
This trial tests whether a combination of vitamins B6, B12, and C can help improve blood flow in tiny blood vessels (microcirculation) for people with sepsis. It may help your body recover better from severe infection.
Chengdu, SichuanAges 18–85 - NCT07419802Recruiting
Study of a special filter for septic shock patients
This trial tests a special blood filter called Oxiris that may help remove toxins and inflammation from the blood in patients with septic shock. It aims to see if this treatment can improve outcomes for people who need kidney replacement therapy.
RigaAges 18 years+ - NCT07411469Recruiting
Comparing heart monitoring methods in sepsis patients
This study compares two methods to measure fluid responsiveness in patients with sepsis and hypotension: cardiometry (non-invasive heart monitoring) and ultrasound of the IVC vein. The goal is to find a simpler way to guide treatment.
Shibīn al Kawm, MenoufiaAges 18–65 - NCT06754696Recruiting
Testing a blood protein in children with and without infection
This study looks at a specific blood protein level in children from birth to age 17. It compares healthy children and those with sepsis to see if the protein changes during infection.
NantesAges Up to 17 years - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT07343206Recruiting
Early norepinephrine for sepsis with low blood pressure
This trial tests whether giving a medicine called norepinephrine early and adjusting the dose quickly can help people with sepsis who have very low blood pressure. It is for adults who are diagnosed within the last 3 hours and who have not already received this medicine.
Bangkok Noi, BangkokAges 18 years+ - NCT05225402Recruiting
Testing blood-flow measurements in ICU shock patients
This trial studies how blood flow and organ “perfusion” look in ICU patients who are struggling with infection and low blood pressure. It may help doctors better measure and manage shock by comparing hemodynamic readings during standard treatment.
Hvidovre, CopenhagenAges 18 years+ - NCT07286643Recruiting
Ultrasound-guided sepsis care for patients with cirrhosis
This study tests whether using a special ultrasound of the heart can guide treatment for sepsis-related low blood pressure in patients with cirrhosis. It aims to improve care and outcomes for critically ill patients.
ChandigarhAges 18–65 - NCT07230041Recruiting
Antibiotic removal during kidney therapy in the ICU
This trial studies how much certain antibiotics (meropenem, linezolid, and daptomycin) are removed when you're on a special blood-filtering machine called continuous renal replacement therapy (CRRT) for severe kidney injury. The results could help doctors give the right dose of antibiotics to treat infections effectively.
Milan, ItaliaAges 18 years+ - NCT06915974Recruiting
Comparing Blood Tests for Sepsis in Burn ICU Patients
This study is comparing two blood tests (Interleukin 6 and Procalcitonin) to find which is better at detecting sepsis (a serious infection) and predicting the risk of death in burn patients in the ICU. If you have moderate burns and are otherwise healthy, this trial could help improve care for burn victims.
CairoAges 25–60 - NCT05575024Recruiting
Monitoring blood pressure and heart rhythm during kidney support in sepsis
This study looks at how stable blood pressure and heart rhythm are in people with sepsis who need continuous kidney filtration. If you qualify, it may help researchers better improve care for critically ill patients receiving this treatment.
SeoulAges 18 years+ - NCT07067866RecruitingPhase 3
Best way to stop vasopressin in sepsis patients
This trial compares two ways to safely stop the vasopressin medication in people with sepsis who are in the ICU. It aims to find the best approach to wean off this blood pressure support, which could help you recover more smoothly.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07063095RecruitingPhase 3
Testing two antibiotics combined for serious bacterial infections
This study tests whether combining two antibiotics (ceftazidime and fosfomycin) works better than ceftazidime alone for hospitalized adults with serious bacterial infections. If you have a severe infection thought to be caused by Gram-negative bacteria, this trial may offer a new treatment option.
Geneva, Canton of GenevaAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06904001Enrolling by invitation
Early warning model for sepsis in critically ill patients
This trial is building a tool to predict sepsis, a life-threatening response to infection, in intensive care patients. It may help doctors act faster to prevent complications.
Wenzhou, ZhejiangAges 18–99
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Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 110 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.