Clinical trials
Severe Infection clinical trials
Below are recruiting severe infection clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07070284Enrolling by invitation
Severe pneumonia in older adults: a study of risks and outcomes
This study looks at older adults with severe pneumonia to understand what causes it and how to improve outcomes. If you are 65 or older and have severe pneumonia, this trial may help doctors learn more about your condition.
Zagreb, City of ZagrebAges 65 years+ - NCT06508502Recruiting
Pancreatitis Severity and Gut Bacteria Study
This study looks at how the bacteria in your gut (microbiome) might affect the severity of a first-time acute pancreatitis attack. It aims to see if certain gut bacteria can predict how serious the illness will be, which could help doctors treat patients better.
Göttingen, Lower SaxonyAges 18 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Little Rock, ArkansasAges 12 years+ - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT05631405Recruiting
Dexamethasone for serious dengue with warning signs
This trial studies whether dexamethasone (a steroid medicine) can help people with dengue infection who have warning signs and are still in the fever stage. It may help reduce complications like breathing problems, severe bleeding, or organ stress, but it is only for a specific window and situation.
BangkokAges 7–99 - NCT05656105RecruitingEarly Phase 1
PET scan study of brain inflammation after COVID
This early-phase study uses a special PET scan to look for signs of brain inflammation in people with ongoing (long-term) nervous system symptoms after COVID-19. It may help researchers understand what is driving symptoms and whether this imaging approach can detect inflammation.
Birmingham, AlabamaAges 18–65 - NCT06751836Recruiting
New ways to treat severe dengue
This trial tests new strategies to treat dengue, ranging from mild to severe cases. It may help people with different stages of dengue find better care and support.
Guatemala CityAges 18 years+ - NCT06928753RecruitingPhase 4
Chikungunya vaccine study in La Réunion
This study is for people who are eligible for the chikungunya vaccine in La Réunion. It looks at how well the vaccine works in real life, if it’s safe, and how your body responds to it.
Saint-DenisAges 18 years+ - NCT05993442Recruiting
Skin-to-skin care to reduce infections in early babies
This study is testing if giving more skin-to-skin care (called Kangaroo Care) to very early-born babies in the NICU can reduce serious infections and the spread of resistant bacteria. It is for babies born before 32 weeks in certain hospitals.
AthensAges Up to 7 months - NCT04448145Recruiting
Study why COVID lasts after recovery
This study looks at what factors may make COVID-19 symptoms or infection effects last after someone has recovered. It also collects certain body samples to better understand why this persistence happens.
New York, New YorkAges 7 years+ - NCT07197164RecruitingPhase 2
Remdesivir for kidney transplant patients with mild COVID-19
This trial tests whether giving remdesivir to kidney transplant patients who test positive for COVID-19 can prevent them from getting severely ill. It is for people who have already had at least three COVID-19 vaccine doses and are scheduled to receive a kidney transplant soon.
Badalona, BarcelonaAges 18 years+ - NCT07379554Recruiting
Infection Risk Prediction After Transplant
This study is for people who have had a stem cell or solid organ transplant. It aims to predict who might get a serious infection and help doctors manage their care better.
Pavia, LombardyAges Any age - NCT07682766Recruiting
Biomarkers of inflammation and infection in critical care
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
TorinoAges 18 years+ - NCT06659588Recruiting
Study of chronic hepatitis risk in people with immune weaknesses
This study looks at people with certain immune system weaknesses to see if they are at risk for chronic hepatitis caused by a virus in the gut. Researchers want to understand how the immune system affects this infection.
ParisAges Any age
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Common questions
- Are there clinical trials for severe infection?
- Yes. Clin2 currently lists 62 recruiting severe infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.