Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06730763Recruiting
Brain stimulation to reduce fall risk in children with cerebral palsy
This study tests whether a gentle, non-invasive brain stimulation (called tDCS) can help children with cerebral palsy (spastic hemiplegia) improve their balance and reduce falls. The goal is to see if it makes walking safer and easier.
Giza, Giza GovernorateAges 8–12 - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06844734Recruiting
Study of ITB treatment for hereditary spastic paraplegia
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Shanghai, Shanghai MunicipalityAges 14–70 - NCT06847295Recruiting
Spinal cord stimulation for standing and walking after paralysis
This trial tests if a device that sends mild electrical pulses to the spinal cord, combined with daily therapy, can help people with chronic spinal cord injury regain some ability to stand or walk. It also looks at reducing muscle spasms and improving quality of life.
São Paulo, São PauloAges 18–50 - NCT06920524Recruiting
Music therapy for stress during botox injections
This study tests whether listening to music can reduce stress and anxiety during botulinum toxin (botox) injections for muscle spasticity. It may help you feel more calm and comfortable during treatment.
Clermont-FerrandAges 18 years+ - NCT06936163Recruiting
Surgery for foot deformities in hereditary spastic paraplegia
This study looks at how well surgery works for foot problems like tight heel cords or clubfoot in people with hereditary spastic paraplegia (HSP), a condition that causes leg stiffness. It aims to see if surgery can improve walking, reduce pain, and prevent falls.
Shanghai, Shanghai MunicipalityAges 10–45 - NCT06937723Recruiting
App-based monitoring for spasticity in multiple sclerosis
This trial tests if a smartphone app can help monitor spasticity (muscle tightness or stiffness) in people with multiple sclerosis. If you have MS and spasticity that needs treatment, using your own smartphone might help track your health.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT06991725Recruiting
Botulinum toxin for children with CP: benefits vs harm
This study looks at how botulinum toxin injections affect the muscles of children with spastic cerebral palsy, comparing them to typically developing children to understand the balance between treatment benefits and potential muscle damage.
Leuven, Vlaams-BrabantAges 2–16 - NCT07034547Recruiting
Botox for children with cerebral palsy
This study tests whether a Botox (botulinum toxin) injection can improve arm and leg movement in children with cerebral palsy. It is for kids ages 8–17 who have stiffness mainly on one side and can walk well.
Santiago, Santiago MetropolitanAges 8–17 - NCT07045519Recruiting
Vibration therapy for walking and balance in cerebral palsy
This study tests whether a gentle vibrating device applied to the legs can improve walking and balance in children with cerebral palsy. It may help reduce muscle tightness and make moving easier.
AnkaraAges 4–18 - NCT07090057Recruiting
Targeting the plantaris muscle in ankle surgery for children
This study tests if removing the plantaris muscle during surgery improves ankle movement in children with tight heel cords. It aims to see if this extra step leads to better outcomes.
Edmonton, AlbertaAges 4–17 - NCT07132775Recruiting
Full-body electrical stimulation suit for spasticity and pain
This study tests a full-body suit that uses mild electrical stimulation to help reduce spasticity, pain, and overactive reflexes in people with conditions like Multiple Sclerosis or Fibromyalgia. It aims to see if the suit is safe and can improve comfort and movement.
Chicago, IllinoisAges 18–75 - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT07159789Recruiting
Brain stimulation to improve leg weakness in MS
This study tests whether a noninvasive brain stimulation technique (rTMS) can help people with multiple sclerosis who have leg stiffness and weakness. You will receive daily sessions over two weeks to see if it improves walking and quality of life.
Gatineau, QuebecAges 18–70 - NCT07167732Recruiting
CTNNB1 Syndrome Natural History Study
This study follows people with CTNNB1 syndrome over time to better understand the condition. It does not test any new treatment—just collects information to help future research.
SydneyAges Any age - NCT07233824Recruiting
Fun-core exercises for balance in children with cerebral palsy
This study tests if fun, child-friendly core stabilization exercises can improve balance and movement in children with spastic cerebral palsy. It may help kids who can walk with or without assistance.
Istanbul, FatihAges 6–12 - NCT07244146Recruiting
Hand therapy for children with spastic cerebral palsy
This trial tests a therapy called CHRIST for children ages 6-12 who have spastic cerebral palsy affecting one side. The goal is to improve hand use and arm function.
Lahore, Punjab ProvinceAges 6–12 - NCT07247812Recruiting
Spinal Cord Stimulation for Hand Function in Young People With Hemiplegic CP
This study tests a new way to help hand movement in young people with hemiplegic cerebral palsy. It uses a gentle electrical current on the spine (called transcutaneous spinal cord stimulation, or tSCS) to see if it can improve hand control and daily function.
LeedsAges 12–21 - NCT07293988Recruiting
Calf muscle stiffness in adults with cerebral palsy
This study looks at a type of muscle stiffness called spastic myopathy in adults with cerebral palsy. It tests whether a specific treatment or evaluation can help improve walking and calf muscle flexibility.
Créteil, Île-de-France RegionAges 18 years+ - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07343752Recruiting
Blood flow restriction therapy for teen flat feet
This study tests whether adding a special blood-flow restriction technique to physical therapy helps teenagers with stiff, spasming flat feet more than physical therapy alone. It is for teens whose flat feet didn't get better with initial treatment.
AsyutAges 10–18 - NCT00001778Recruiting
Understanding HTLV Infection and HAM/TSP Disease
This research study evaluates people with HTLV infection, a virus that can cause a nerve disorder called HAM/TSP. Researchers want to better understand who gets this condition and why, which may help develop future treatments.
Bethesda, MarylandAges 18–120 - NCT07417943Recruiting
Brain stimulation to improve movement in hereditary spastic paraplegia
This study tests whether a non-invasive brain stimulation technique (called neuromodulation) can improve walking, balance, and other movements in adults with hereditary spastic paraplegia (HSP). It may be a good fit if you can walk with or without help, have stable spasticity medications, and don't have a pacemaker or epilepsy.
Lexington, KentuckyAges 18 years+
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 154 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.