Clinical trials
Spasticity, Muscle clinical trials
Below are recruiting spasticity, muscle clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06902168Recruiting
Diving and pool exercises for muscle tightness in kids with cerebral palsy
This study tests whether diving and swimming-type exercises can help reduce muscle stiffness and improve movement in young children with spastic cerebral palsy. It is for children ages 2 to 5 who have significant mobility challenges (GMFCS levels IV or V).
Banhā, BenhaAges 2–5 - NCT05447299Enrolling by invitation
Muscle and spasticity testing using MRI modeling
This study uses an MRI scan and movement measurements to better understand muscle tightness (spasticity) in children with cerebral palsy. It may help researchers improve how spasticity is evaluated and modeled to support future treatments.
StockholmAges 5–18 - NCT05506228Recruiting
Muscle biopsy during surgery study in brain injury conditions
This study looks at how muscles are affected in children and teens with cerebral palsy or an acquired brain injury. Researchers take a small muscle tissue sample during surgery that you were already having for medical reasons, to better understand muscle changes.
StockholmAges 2–18 - NCT07118228Recruiting
Ultrasound study of muscle in children with spastic cerebral palsy
This study uses ultrasound to look at muscle shape and function in children with spastic cerebral palsy. It aims to see how these muscle features relate to movement abilities, which could help guide future treatments.
KocaeliAges 4–18 - NCT05497609Recruiting
Study of tiny muscle changes in children with cerebral palsy
This study follows children with cerebral palsy (and sometimes acquired brain injury) to learn how the muscles look and change over time at a very small, microscopic level. The results may help researchers better understand what’s happening in the muscles and guide future treatments.
StockholmAges 2–18 - NCT05518565Recruiting
Study muscle changes in people with cerebral palsy
This study looks at how muscles work in the body in people with cerebral palsy or an acquired brain injury. It may help researchers understand muscle structure and changes over time, which could guide future treatments.
StockholmAges 2–18 - NCT05147441Recruiting
Freezing the obturator nerve for tight hip muscles
This trial looks at cryoneurotomy, a procedure that “freezes” a nerve, to reduce spasticity (tight, stiff muscles) in the hip adductors. It may help some people with spasticity who are already receiving this standard nerve-freezing treatment as part of their care.
Victoria, British ColumbiaAges 12 years+ - NCT06281223Recruiting
Brain and spinal cord connection study in spasticity
This study looks at how the brain and spinal cord connect in children with spasticity (muscle stiffness). It will help doctors understand more about this condition by studying patients who are already scheduled for surgery to reduce stiffness.
NiceAges 3–17 - NCT03384927Enrolling by invitation
Dairy intake study for muscle stiffness in spasticity
This trial looks at whether eating dairy can reduce spasticity, or muscle stiffness/tightness. It’s testing dairy as an add-on by comparing your muscle symptoms and treatment goals during the study.
Glostrup MunicipalityAges Any age - NCT06070233Recruiting
Radiosurgery for spasticity after stroke or injury
This trial tests a non-invasive radiation treatment (radiosurgery) to reduce severe muscle stiffness (spasticity) that hasn't improved with other treatments. It may help people with spasticity caused by stroke, spinal cord injury, or cerebral palsy.
Winter Park, FloridaAges 16 years+ - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99 - NCT06365476Recruiting
Shockwave therapy for arm stiffness after stroke
This trial tests whether shockwave therapy (gentle sound waves) can help relax stiff wrist and finger muscles after a stroke. It is for adults who have had one stroke and have noticeable muscle tightness in their arm.
Taipei, TaipeiAges 18 years+ - NCT07007858Enrolling by invitation
Stretch therapy for leg stiffness in kids with CP
This trial tests if a fast, gentle stretching technique can reduce leg stiffness and improve walking in children with cerebral palsy (CP). It may be an option for children who are already planning to receive Botox injections for tight calf muscles.
Kayseri, TurkeyAges 2–8 - NCT06733025Recruiting
Comparing surgery and Botox for arm spasticity
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
MölndalAges 18 years+ - NCT05354622Recruiting
Genetic testing study for inherited leg stiffness
This study looks at genes (DNA) to understand an inherited condition that causes gradually worsening leg stiffness. It may help researchers learn what causes the condition and potentially guide future care.
Boston, MassachusettsAges 1 month–30 years - NCT05518188RecruitingPhase 1/Phase 2
Gene therapy trial for a childhood AP4M1 brain disorder
This trial studies a one-time gene therapy meant to help children with SPG50 disease caused by changes in the AP4M1 gene. Researchers will give the treatment and closely monitor safety and early signs of benefit.
Dallas, TexasAges 4 months–10 years - NCT06547684Recruiting
Shock wave therapy for foot stiffness after stroke
This trial tests whether shock wave therapy can help relax the tight calf muscles that cause foot drop after a stroke. It may help you walk better and reduce foot stiffness.
Vila-real, CastellonAges 18 years+ - NCT06674785Recruiting
Shock wave therapy for shoulder spasticity after stroke
This trial tests if shock wave therapy can reduce shoulder stiffness caused by a stroke. It may help improve shoulder movement and daily comfort.
TaipeiAges 18 years+ - NCT03096197Recruiting
Exoskeleton and spinal stimulation for long-term spinal cord injury
This trial tests whether an external walking-assist device (an exoskeleton) plus targeted spinal cord stimulation can help people with long-term spinal cord injury. It may be designed for wheelchair users who meet specific nerve function and bone health requirements.
West Orange, New JerseyAges 18–65 - NCT05094362Recruiting
Training to reduce stiff leg reflexes after spinal cord injury
This study tests a special training approach designed to calm overactive leg reflexes (spasticity) after spinal cord injury. If you qualify, you may do structured walking/reflex training to see whether your leg reflexes and movement improve.
Charleston, South CarolinaAges 18 years+ - NCT06109129Recruiting
Mollii Suit study for children with cerebral palsy who can walk
This trial tests whether wearing a special suit (Mollii suit) helps children with cerebral palsy who can walk move better and feel less discomfort. It aims to see if the suit can improve daily life.
AnkaraAges 4–18 - NCT07108920Recruiting
Balance and Botox for Stiff Knee Gait
This study tests whether botulinum toxin (Botox) injections into the rectus femoris thigh muscle can improve balance and walking in people with a stiff knee gait (a common problem after stroke, brain injury, or multiple sclerosis).
Héricourt, Nord Franche-ComtéAges 18 years+ - NCT06044168Recruiting
Nutritional supplement for muscle growth in cerebral palsy
This study tests whether a nutritional supplement can help build muscle in children with spastic cerebral palsy. It may be a good fit if you have trouble with walking and have not had certain treatments recently.
Leuven, Vlaams-BrabantAges 4–10 - NCT06584851Recruiting
3D muscle study in children with cerebral palsy
This study uses a special 3D microscope to look at muscle structure in children with cerebral palsy. It aims to understand muscle stiffness by comparing tiny muscle samples taken during a scheduled procedure that already requires general anesthesia.
Leuven, Vlaams-BrabantAges 2–9
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Common questions
- Are there clinical trials for spasticity, muscle?
- Yes. Clin2 currently lists 34 recruiting spasticity, muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity, muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity, muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.