Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07451600Recruiting
TMS for spasticity and balance in multiple sclerosis
This study tests if transcranial magnetic stimulation (TMS) can help reduce muscle stiffness (spasticity) and improve balance in people with multiple sclerosis. TMS uses magnetic pulses to stimulate parts of the brain.
Ankara, YenimahalleAges 18–60 - NCT07417943Recruiting
Brain stimulation to improve movement in hereditary spastic paraplegia
This study tests whether a non-invasive brain stimulation technique (called neuromodulation) can improve walking, balance, and other movements in adults with hereditary spastic paraplegia (HSP). It may be a good fit if you can walk with or without help, have stable spasticity medications, and don't have a pacemaker or epilepsy.
Lexington, KentuckyAges 18 years+ - NCT06730763Recruiting
Brain stimulation to reduce fall risk in children with cerebral palsy
This study tests whether a gentle, non-invasive brain stimulation (called tDCS) can help children with cerebral palsy (spastic hemiplegia) improve their balance and reduce falls. The goal is to see if it makes walking safer and easier.
Giza, Giza GovernorateAges 8–12 - NCT06847295Recruiting
Spinal cord stimulation for standing and walking after paralysis
This trial tests if a device that sends mild electrical pulses to the spinal cord, combined with daily therapy, can help people with chronic spinal cord injury regain some ability to stand or walk. It also looks at reducing muscle spasms and improving quality of life.
São Paulo, São PauloAges 18–50 - NCT06844734Recruiting
Study of ITB treatment for hereditary spastic paraplegia
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Shanghai, Shanghai MunicipalityAges 14–70 - NCT07343752Recruiting
Blood flow restriction therapy for teen flat feet
This study tests whether adding a special blood-flow restriction technique to physical therapy helps teenagers with stiff, spasming flat feet more than physical therapy alone. It is for teens whose flat feet didn't get better with initial treatment.
AsyutAges 10–18 - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07293988Recruiting
Calf muscle stiffness in adults with cerebral palsy
This study looks at a type of muscle stiffness called spastic myopathy in adults with cerebral palsy. It tests whether a specific treatment or evaluation can help improve walking and calf muscle flexibility.
Créteil, Île-de-France RegionAges 18 years+ - NCT07287215Recruiting
Motor imagery and daily function in diplegic cerebral palsy
This study tests whether imagining movements (motor imagery) can help improve everyday skills like walking and playing in children with diplegic cerebral palsy. It compares the effects of motor imagery training with standard physical therapy.
BingoelAges 5–18 - NCT07286435Recruiting
Vibration therapy after botox for stroke spasticity
This trial tests if adding whole-body vibration therapy to botulinum toxin A (Botox) injections can improve muscle stiffness, balance, and walking in stroke survivors. It may help reduce spasticity and make daily activities easier.
Bursa, BursaAges 18–75 - NCT06539520Recruiting
Walking exercise for heart and lung health after stroke
This trial tests whether a supervised walking and exercise program can improve your heart and lung fitness and overall quality of life after a stroke. It is designed for people who are still affected by weakness on one side but can walk on their own.
GizaAges 55–65 - NCT06598683Recruiting
Brain stimulation for muscle stiffness after stroke
This study tests whether a gentle, non-invasive brain stimulation (tDCS) can help reduce muscle stiffness and improve arm or leg movement in people who had a stroke. If you have tight or stiff muscles after your stroke, this might be a good option to explore.
Rawalpindi, Punjab ProvinceAges 30–70 - NCT07244146Recruiting
Hand therapy for children with spastic cerebral palsy
This trial tests a therapy called CHRIST for children ages 6-12 who have spastic cerebral palsy affecting one side. The goal is to improve hand use and arm function.
Lahore, Punjab ProvinceAges 6–12 - NCT07247812Recruiting
Spinal Cord Stimulation for Hand Function in Young People With Hemiplegic CP
This study tests a new way to help hand movement in young people with hemiplegic cerebral palsy. It uses a gentle electrical current on the spine (called transcutaneous spinal cord stimulation, or tSCS) to see if it can improve hand control and daily function.
LeedsAges 12–21 - NCT06936163Recruiting
Surgery for foot deformities in hereditary spastic paraplegia
This study looks at how well surgery works for foot problems like tight heel cords or clubfoot in people with hereditary spastic paraplegia (HSP), a condition that causes leg stiffness. It aims to see if surgery can improve walking, reduce pain, and prevent falls.
Shanghai, Shanghai MunicipalityAges 10–45 - NCT06937723Recruiting
App-based monitoring for spasticity in multiple sclerosis
This trial tests if a smartphone app can help monitor spasticity (muscle tightness or stiffness) in people with multiple sclerosis. If you have MS and spasticity that needs treatment, using your own smartphone might help track your health.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07167732Recruiting
CTNNB1 Syndrome Natural History Study
This study follows people with CTNNB1 syndrome over time to better understand the condition. It does not test any new treatment—just collects information to help future research.
SydneyAges Any age - NCT07159789Recruiting
Brain stimulation to improve leg weakness in MS
This study tests whether a noninvasive brain stimulation technique (rTMS) can help people with multiple sclerosis who have leg stiffness and weakness. You will receive daily sessions over two weeks to see if it improves walking and quality of life.
Gatineau, QuebecAges 18–70 - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT07132775Recruiting
Full-body electrical stimulation suit for spasticity and pain
This study tests a full-body suit that delivers gentle electrical pulses to help reduce muscle stiffness, spasms, and pain in people with conditions like multiple sclerosis, fibromyalgia, or other neurological problems. It may help with movement and comfort.
Chicago, IllinoisAges 18–75 - NCT07108920Recruiting
Balance and Botox for Stiff Knee Gait
This study tests whether botulinum toxin (Botox) injections into the rectus femoris thigh muscle can improve balance and walking in people with a stiff knee gait (a common problem after stroke, brain injury, or multiple sclerosis).
Héricourt, Nord Franche-ComtéAges 18 years+ - NCT07090057Recruiting
Targeting the plantaris muscle in ankle surgery for children
This study tests if removing the plantaris muscle during surgery improves ankle movement in children with tight heel cords. It aims to see if this extra step leads to better outcomes.
Edmonton, AlbertaAges 4–17
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 153 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.