Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05878223Recruiting
Testing different shockwave doses for ankle stiffness after stroke
This study compares different doses of shockwave treatment to reduce ankle muscle tightness (spasticity) after stroke. If you have persistent ankle stiffness and can safely receive the treatment, your results may help find the best dose for symptom relief.
HsinchuAges 20 years+ - NCT06044168Recruiting
Nutritional supplement for muscle growth in cerebral palsy
This study tests whether a nutritional supplement can help build muscle in children with spastic cerebral palsy. It may be a good fit if you have trouble with walking and have not had certain treatments recently.
Leuven, Vlaams-BrabantAges 4–10 - NCT06059872Recruiting
Study of high-intensity interval training after stroke
This study tests whether a high-intensity interval training (HIIT) exercise program can help people with walking difficulties after a stroke. It looks for veterans who have had a stroke at least 6 months ago and walk slowly, to see if this type of exercise can improve their recovery.
Decatur, GeorgiaAges 18–89 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06109129Recruiting
Mollii Suit study for children with cerebral palsy who can walk
This trial tests whether wearing a special suit (Mollii suit) helps children with cerebral palsy who can walk move better and feel less discomfort. It aims to see if the suit can improve daily life.
AnkaraAges 4–18 - NCT06128746Recruiting
Brain stimulation for muscle tightness in children with cerebral palsy
This trial tests a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to see if it can reduce muscle tightness (spasticity) in the arm of children with cerebral palsy or hemiplegia caused by a brain injury. It is a randomized controlled trial, meaning some children will receive the active treatment and others a placebo, to find out if it really helps.
Hong Kong, Hong KongAges 7–18 - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT06214208Recruiting
Spinal stimulation frequencies for spasticity after spinal cord injury
This study tests how different frequencies of spinal stimulation affect spasticity, movement, and pain after a spinal cord injury. It may help if you have leg spasticity and no implanted devices.
Atlanta, GeorgiaAges 16 years+ - NCT06296082RecruitingPhase 2/Phase 3
Dry Needling vs Botox for Post-Stroke Leg Stiffness
This study compares two treatments for leg stiffness after a stroke: dry needling (tiny needles placed in trigger points) and Botox injections. It may help you if you've had a first stroke within the past year and have mild to moderate tightness in the calf muscles that limits ankle movement.
Antwerp, FlandersAges 18–75 - NCT06330922Recruiting
Muscle and tendon health study in cerebral palsy
This study looks at muscle and tendon health in people with spastic cerebral palsy who are mildly to severely affected. It involves using a special running frame to see how it affects the body.
GrazAges 14–30 - NCT06394310Recruiting
Dry needling for leg tightness in MS
This study tests whether dry needling (a therapy using thin needles to release muscle tightness) can help reduce leg stiffness and improve walking in people with multiple sclerosis. If you have leg spasticity and can walk with some help, this trial may be a good fit.
Kansas City, KansasAges 18–64 - NCT06454656Recruiting
Walking practice for kids with Cerebral Palsy
This study tests a motor learning program to help children with Cerebral Palsy improve their walking. If your child has a walking goal and a caregiver who can help at home, this could be a good fit.
Balrath, MeathAges 6–17 - NCT06494020Recruiting
Hand task practice with spinal cord stimulation
This study tests whether practicing hand and arm tasks while using spinal cord stimulation can improve movement and function for people with chronic cervical spinal cord injury.
Miami, FloridaAges 22–70 - NCT06531044Recruiting
Motor coordination and balance in children with cerebral palsy
This study looks at how well children with spastic cerebral palsy can coordinate their movements and keep their balance. It may help find new ways to improve movement and prevent falls.
IsmailiaAges 5–11 - NCT06532981Recruiting
How Ankle-Foot Braces Affect Muscle Activity in Children with CP
This study looks at how ankle-foot braces (AFOs) affect the electrical activity in the leg muscles of children with cerebral palsy. It may help understand if braces improve muscle function during walking.
Leuven, Vlaams-BrabantAges 6–17 - NCT06539520Recruiting
Walking exercise for heart and lung health after stroke
This trial tests whether a supervised walking and exercise program can improve your heart and lung fitness and overall quality of life after a stroke. It is designed for people who are still affected by weakness on one side but can walk on their own.
GizaAges 55–65 - NCT06543758RecruitingPhase 4
Gait rehab with a wearable robot at home
This trial tests whether using a wearable robotic device at home can improve walking ability in people who have had a stroke. If you have trouble walking due to a stroke, this study may help you regain strength and mobility.
Yongin-si, Gyeonggi-doAges 19–79 - NCT06584851Recruiting
3D muscle study in children with cerebral palsy
This study uses a special 3D microscope to look at muscle structure in children with cerebral palsy. It aims to understand muscle stiffness by comparing tiny muscle samples taken during a scheduled procedure that already requires general anesthesia.
Leuven, Vlaams-BrabantAges 2–9 - NCT06598683Recruiting
Brain stimulation for muscle stiffness after stroke
This study tests whether a gentle, non-invasive brain stimulation (tDCS) can help reduce muscle stiffness and improve arm or leg movement in people who had a stroke. If you have tight or stiff muscles after your stroke, this might be a good option to explore.
Rawalpindi, Punjab ProvinceAges 30–70 - NCT06640894Recruiting
Power2Walk: strength training for kids with cerebral palsy
This study tests a type of strength training called functional power training for children with cerebral palsy. The goal is to see if it helps kids be more active and take part in daily activities.
Emmen, DrentheAges 4–12 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06673849Recruiting
Rhythmic Stabilization vs. Ball Balancing for CP Children
This study compares two therapy techniques—rhythmic stabilization and ball balancing—to see which helps children with spastic diplegia CP improve balance and movement. It's for children aged 6 to 12 with mild spasticity and normal intelligence.
Lahore, Punjab ProvinceAges 6–12 - NCT06692712RecruitingPhase 3
Gene therapy study for children with SPG50
This study tests a gene therapy called IT MELPIDA for children with SPG50, a genetic condition that affects movement and development. The treatment is given through a lumbar puncture (spinal tap) and aims to slow or stop the loss of motor skills.
Dallas, TexasAges 4 months–6 years - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 155 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.