Clinical trials
Stenosis clinical trials
Below are recruiting stenosis clinical trials, each written for real people, not researchers. We’re tracking 495 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03972644Recruiting
Early valve replacement for people with severe but silent aortic narrowing
This trial tests whether replacing a badly narrowed aortic valve earlier—even when you feel fine—can prevent future heart problems. It compares early valve replacement (through a catheter or surgery) versus standard watchful waiting.
Odense, FynAges 18–85 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80 - NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
BeijingAges 70 years+ - NCT04722796Recruiting
TAVR for bicuspid aortic valve with a specific device
This study tests a “solution” approach using a self-expanding valve during TAVR (a less invasive way to replace a narrowed aortic valve). It aims to improve how well the valve fits and works in people with a specific heart valve shape (bicuspid aortic stenosis).
Bengbu, AnhuiAges 60 years+ - NCT05550077Recruiting
Imaging study for narrowed brain arteries after stroke
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05629000Recruiting
Study of treatment planning after carotid artery narrowing
This study looks at an approach to better plan treatment for people with significant narrowing of the carotid artery (the main artery to the brain). It may help doctors choose safer, more effective care after surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05629104Recruiting
Predicting long-term outcomes after aortic valve procedure
This study follows people who have aortic valve treatment to better predict how they will do in the long term. It may help doctors understand what outcomes to expect after the procedure and improve future care.
UppsalaAges 18 years+ - NCT05644314Recruiting
Drug-coated stent for narrowed vertebral arteries
This trial studies whether a drug-coated stent placed in a narrowed vertebral artery can improve outcomes for people with artery narrowing from plaque. It also looks at how safe the stent is, since it requires specific blood-thinning medicines around the procedure.
Guangzhou, GuangdongAges 18 years+ - NCT05778773Recruiting
Study of treatment outcomes for severe aortic valve narrowing
This study looks at how well current treatment choices work for older adults with severe aortic valve narrowing (stenosis). It may help doctors better understand what works best for aging patients in Italy.
San Donato Milanese, MIAges 65 years+ - NCT05322824Recruiting
Study for adults with narrowed brain or neck arteries
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05244629Recruiting
Compare two stents for chronic artery-related gut pain
This trial tests whether an uncovered stent or a covered stent works better for treating chronic mesenteric ischemia (reduced blood flow to the intestines from artery narrowing). It’s meant for adults with symptoms and scans showing significant narrowing in a specific gut artery.
København ØAges 18 years+ - NCT05961748Recruiting
Brain and heart illness registry for adults in China
This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06085612Recruiting
How carotid artery blockage affects blood flow in the retina
This trial examines how a narrowing of the main neck artery (carotid stenosis) impacts blood flow in the retina using a special eye test called automated retinal oximetry. The goal is to better understand how this blockage affects eye health.
OlomoucAges 18 years+ - NCT06136429Recruiting
A study of a new valve device for severe aortic stenosis
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
BeijingAges 70 years+ - NCT05310461Recruiting
Early or delayed valve surgery for mixed heart valve disease
This study compares doing aortic valve replacement sooner versus waiting, in people with moderate aortic valve narrowing plus at least moderate leakage in the mitral valve. It aims to see which timing improves heart symptoms and outcomes while keeping treatment safe.
BernAges 18 years+ - NCT07855419Recruiting
Muscle loss and steroid injections for lumbar spinal stenosis
This study looks at whether the amount of muscle loss (sarcopenia) affects how well steroid injections into the spine work for people with lumbar spinal stenosis, a condition that causes back and leg pain from narrowing of the spinal canal.
Istanbul, IstanbulAges 50–75 - NCT07855445Recruiting
Nerve pain and MRI findings in lumbar spinal stenosis
This study looks at how nerve pain relates to MRI results in people with lumbar spinal stenosis, a condition where the spinal canal narrows and presses on nerves. It aims to better understand the link between symptoms and imaging, which could help improve care.
Istanbul, IstanbulAges 18 years+ - NCT04703699Recruiting
Study of a heart valve implant after 30 days
This study looks at people who already received the Myval THV heart valve implant for severe native aortic valve narrowing. It checks how patients are doing after at least 30 days of follow-up to better understand the valve’s performance.
TallinnAges 18 years+ - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT04968509RecruitingPhase 3
PCSK9 shots for calcified aortic valve narrowing
This study tests whether adding PCSK9 inhibitor injections (to statin treatment) can slow or improve calcific aortic valve stenosis, a condition where the heart’s aortic valve becomes stiff and narrowed. It’s aimed at adults with mild-to-moderate disease or certain people with severe disease but no symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03003299Recruiting
Valve replacement for failing aortic bioprosthetic valves
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
Phoenix, ArizonaAges Any age - NCT07827105Enrolling by invitation
AI heart test for undiagnosed aortic stenosis
This study uses an artificial intelligence (AI) tool to analyze electrocardiograms (ECGs, which record the heart's electrical activity) to find people who may have a heart valve condition called aortic stenosis, which can make the heart work harder. The goal is to help detect this condition earlier in people who haven't been diagnosed yet.
Orange, CaliforniaAges 65 years+ - NCT06319846RecruitingPhase 3
Tirofiban for recent mild stroke or TIA with narrowed brain artery
This trial tests the drug tirofiban (a blood thinner) to prevent another stroke in people who have had a mild stroke or high-risk TIA and have a narrowed artery in the brain. It must be started within 24 hours of symptoms.
Harbin, HeilongjiangAges 40 years+ - NCT06447740Recruiting
Stent vs. medication for narrowed kidney artery
This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for stenosis?
- Yes. Clin2 currently lists 495 recruiting stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.