Clinical trials
Subjective Cognitive Impairment clinical trials
Below are recruiting subjective cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT05305092Recruiting
Study of memory and thinking in early breast cancer
This study checks how breast cancer affects memory and thinking before other treatments start. It may help doctors better understand cognitive changes and who is most at risk.
Xi'an, ShaanxiAges Any age - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT05510401Recruiting
Safe use study of an at-bed safety mattress system
This study checks whether a special bed-safety device (SÉCURIDRAP® SELFIA®) can be used safely for adults who get confused, move at night, or are at risk of falling out of bed. You may be able to join if you already have a prescription for the device and meet other safety and consent requirements.
BailleulAges 18 years+ - NCT05597410Recruiting
Study of people at risk for Alzheimer’s in Shanghai
This study follows people who are closely related to someone diagnosed with Alzheimer’s to see who develops memory or brain changes over time. It may help researchers understand risk and early signs, which could guide prevention in families like yours.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT05606341RecruitingPhase 1
Testing a diabetes-style shot to boost brain immunity in early Alzheimer’s
This Phase 1 study tests whether stimulating the immune system (through a receptor called TLR9) is safe and may affect brain changes in people with early Alzheimer’s. It mainly enrolls older adults with memory impairment confirmed by specific amyloid imaging.
New York, New YorkAges 60–85 - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT06342661Recruiting
VISTA protein in blood vessel-related memory problems
This study measures levels of a protein called VISTA in the blood of people with memory problems caused by blood vessel disease. It aims to see if VISTA can help diagnose or predict this condition.
Harbin, HeilongjiangAges 50–80 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT06489548RecruitingPhase 2
Foralumab for Early Alzheimer's Disease
This study tests an experimental drug called Foralumab, which aims to calm overactive immune cells in the brain linked to Alzheimer's. It may help slow memory loss in people with early-stage Alzheimer's.
Boston, MassachusettsAges 60–85 - NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels
This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.
Shenyang, LiaoningAges 50–80 - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06541834Recruiting
Predicting diabetes eye nerve problems with retina scans
This study uses artificial intelligence to analyze retinal images and predict the risk of nerve-related problems caused by diabetes. It may help identify those at risk before symptoms appear.
MilanAges 45 years+ - NCT06572748Recruiting
Cooking study for older adults with memory concerns
This study tests a cooking program called Chef Anchor 3.0 for older adults with mild memory problems or dementia. It looks at whether learning to cook can help with thinking skills and daily life.
Hong KongAges 60 years+ - NCT06592352RecruitingPhase 2
Modafinil for thinking problems in MS
This study tests whether the medication modafinil can improve thinking and memory problems in people with MS. If you have MS and notice cognitive changes like forgetfulness or trouble focusing, you may be eligible.
BragaAges 18–64 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06619613RecruitingPhase 1
Study of CM383 for early Alzheimer's disease
This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.
HefeiAges 50–85 - NCT06639282RecruitingPhase 2
Testing siponimod for mild Alzheimer's dementia
This study tests if a medicine called siponimod, already used for multiple sclerosis, can help people with mild Alzheimer's dementia. You will take a pill daily and be monitored closely for safety and cognitive changes.
Phoenix, ArizonaAges 50–85 - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+ - NCT06968039Recruiting
Personalized brain stimulation for cognitive issues in demyelinating diseases
This trial tests a personalized form of electrical brain stimulation to improve cognitive problems like memory and thinking speed in people with conditions that damage the protective coating around nerves. It aims to see if this treatment can help with day-to-day thinking challenges.
Beijing, Beijing MunicipalityAges 18–65 - NCT07058688RecruitingPhase 2
Testing a new drug for Alzheimer's (NTRX-07)
This study tests an experimental drug for Alzheimer's called NTRX-07. It aims to see if it can slow memory decline for people with mild to moderate Alzheimer's.
BrnoAges 65–80
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Common questions
- Are there clinical trials for subjective cognitive impairment?
- Yes. Clin2 currently lists 195 recruiting subjective cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a subjective cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a subjective cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.