Clinical trials
Surgical Resection clinical trials
Below are recruiting surgical resection clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06487481RecruitingPhase 1
Radiation before surgery for recurrent adrenal cancer
This trial tests whether giving radiation before surgery helps people with adrenal cancer that has come back after previous treatment. It aims to see if this approach can improve outcomes for patients who can have surgery at the NIH.
Bethesda, MarylandAges 18–120 - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT05582265RecruitingPhase 3
Study immune drug plus chemo before surgery versus surgery first
This Phase 3 trial compares two treatment plans for stage III/IVA head and neck squamous cell cancer (HNSCC). One plan uses an immune drug with chemotherapy before surgery; the other goes straight to surgery first, to see which approach works better.
Guanzhou, GuangdongAges 18–80 - NCT05671458Recruiting
Imaging guidance during head and neck tumor surgery plus radiation
This trial tests whether advanced imaging used during surgery can better guide where surgeons remove head-and-neck tumors. It also studies how this approach works alongside planned postoperative radiation therapy, which may be needed for more advanced tumors.
HeidelbergAges 18 years+ - NCT06323369RecruitingPhase 2
Tislelizumab plus chemo before surgery vs surgery alone for head and neck cancer
This trial tests whether giving tislelizumab (an immunotherapy) with chemotherapy before surgery works better than surgery alone for people with head and neck cancer that has not spread to lymph nodes. It's for cancers that can be removed with surgery, and the goal is to see if the pre-surgery treatment improves outcomes.
Guangzhou, YuexiuAges 18–75 - NCT05098119RecruitingPhase 2
Study drugs before surgery for mouth or throat cancer
This Phase 2 trial tests giving the immunotherapy drug sintilimab before surgery, along with fewer chemotherapy cycles. The goal is to shrink or control oral or throat squamous cell cancers while keeping side effects lower, before the tumor is removed.
Guangzhou, GuangdongAges 18–80 - NCT07650656RecruitingPhase 2
Fluorescence-Guided Surgery to Improve Sarcoma Tumor Removal
This trial tests a special dye and imaging technique to help surgeons see and remove sarcoma tumors more completely. The goal is to reduce the chance that cancer cells are accidentally left behind during surgery.
Duarte, CaliforniaAges Any age - NCT01898416RecruitingPhase 2
5-ALA by mouth to reduce regrowth of desmoid tumors
This Phase 2 trial tests whether taking a medicine called 5-ALA by mouth after treatment can lower how often desmoid tumors come back in the same area. If you have a desmoid tumor that can be removed and you meet safety criteria, this study may help determine whether 5-ALA is effective and safe for you.
Tel Aviv, IsraelAges 18 years+ - NCT04807140RecruitingPhase 2
Study of toripalimab before surgery for head and neck cancer
This trial tests toripalimab (an immunotherapy) given before surgery for untreated head and neck squamous cell carcinoma, either alone or with chemotherapy. The goal is to shrink or control the cancer earlier and see if it improves outcomes for people who plan curative surgery.
Guangzhou, GuangdongAges 18–80 - NCT06255197Recruiting
Study of lung cancer surgery patients and their outcomes
This study looks at the characteristics, treatments, and results of people who have had surgery to remove lung cancer. It aims to help doctors understand what happens after surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04810871Recruiting
Surgery for brain tumors that may come back
This study tests whether removing a brain tumor early, before it shows signs of growing back, can help prevent a recurrence. If you have had treatment before and there is still some tumor left, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT05701514Recruiting
Test in babies with a prenatal lung cyst found on scans
This trial is for newborns who are found before birth to have a congenital lung cyst (CPAM) and who stay symptom-free. It tests an approach for babies with certain CPAM features to see if it’s safer and/or more effective than standard care.
Nijmegen, GelderlanfAges 1 month–1 year - NCT05984810RecruitingPhase 2
Using a glowing dye to help see pancreatic cancer during surgery
This trial tests whether a special dye (SGM-101) can help surgeons see remaining cancer cells during surgery for pancreatic cancer that has been treated before surgery. It may lead to more complete removal of the tumor.
LeidenAges 18 years+ - NCT06366828Recruiting
Predicting complications after esophageal cancer treatment
This study looks at past medical records of people with esophageal cancer who received chemotherapy and radiation before surgery. Researchers want to find better ways to predict who might have complications after surgery, so they can improve care for future patients.
Nijmegen, GelderlandAges 18–100 - NCT07797816RecruitingPhase 2
Targeted drug combo with radiation for advanced bile duct cancer
This trial tests a combination of two chemotherapy drugs and an immunotherapy drug, followed by targeted radiation, in people with bile duct or gallbladder cancer that cannot be removed with surgery. The goal is to see if this approach can shrink tumors and improve outcomes.
Nanjing, JiangsuAges 18–80 - NCT06560827RecruitingPhase 1
CAR-T Cells for Liver Cancer After Surgery
This trial is testing a new treatment made from your own immune cells (called CT011 CAR-T cells) to see if it can lower the risk of liver cancer coming back after surgery. It is designed for people with advanced liver cancer that has spread into nearby blood vessels.
BeijingAges 18–75 - NCT05487391RecruitingPhase 3
QL1706 plus chemo after lung cancer surgery
This trial studies whether a study drug called QL1706 added to standard platinum chemotherapy can lower the chance of lung cancer coming back after surgery. It targets people with stage II to IIIB non-small cell lung cancer who have had their tumor fully removed.
ShanghaiAges 18 years+ - NCT06690528RecruitingPhase 2
Surgery vs. palliative care for pancreatic cancer with limited liver spread
This trial compares surgery to remove the primary tumor and up to 3 liver spots against standard palliative care for people with pancreatic cancer that has spread only to the liver (up to 3 spots). It is for those whose cancer has not grown after initial chemotherapy and who are healthy enough for surgery.
Padova, ItalyAges 18–75 - NCT07549399RecruitingPhase 3
Radiation, Chemotherapy, and Immunotherapy for Rectal Cancer
This trial tests a combination of radiation, chemotherapy, and immunotherapy drugs before surgery for people with locally advanced rectal cancer. The goal is to shrink the tumor and improve outcomes for patients with higher-risk disease.
Guangzhou, GuangdongAges 18–75 - NCT06709833Recruiting
Blood clot risk study for brain tumor patients
This study looks at blood clotting risks in people having surgery for meningioma or glioma brain tumors, and compares them to healthy volunteers. It may help doctors better understand and prevent blood clots after brain tumor surgery.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07511725RecruitingPhase 2
Thiotepa spinal injection to prevent glioblastoma spread
This trial tests whether injecting a chemotherapy drug called thiotepa into the fluid around the brain and spine can prevent glioblastoma from spreading in patients whose tumor touches the fluid-filled spaces or who had a leak during surgery.
Hangzhou, ZhejiangAges 18–75 - NCT07455032RecruitingPhase 1
Neoadjuvant therapy combo for head and neck cancer
This trial tests a combination of two drugs (CADI-05 and pembrolizumab) before surgery for people with a certain type of head and neck cancer that hasn't spread. The goal is to see if this treatment can help shrink the tumor before it is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07460999Recruiting
Singing training after lung cancer surgery
This trial tests if singing training twice a week can help with ongoing symptoms like shortness of breath or fatigue 6 to 18 months after surgery for early-stage lung cancer.
CopenhagenAges 18 years+ - NCT07410715Recruiting
Surgery or observation after successful liver cancer treatment
This study compares surgery versus watch-and-wait for people whose liver cancer shrank significantly after treatment. It aims to find out if surgery is always needed or if watching closely is just as good.
ChengduAges 18–80
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Common questions
- Are there clinical trials for surgical resection?
- Yes. Clin2 currently lists 112 recruiting surgical resection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical resection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical resection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.