Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05625373RecruitingPhase 2/Phase 3
Antibiotic powder during groin surgery to prevent infection
This trial studies whether placing an antibiotic powder (vancomycin) directly in the surgical wound during groin lymph node surgery can lower the risk of surgical site infections. It may help reduce wound infections after surgery for vulvar dysplasia.
Providence, Rhode IslandAges 18 years+ - NCT06161779Recruiting
Reconstructing the hypopharynx after cancer removal
This trial tests a surgical technique using a flap from under your chin to rebuild the hypopharynx after removing cancer. It may help people with hypopharyngeal cancer that has not spread far and who have not had radiation before.
Guangzhou, GuangdongAges 18–80 - NCT06127719Recruiting
Surgery wait time and knee replacement quality of life
This study looks at how waiting for knee replacement surgery affects your quality of life. It may help doctors understand how to improve care for people waiting for surgery.
Hoorn, North HollandAges 18–100 - NCT05847270Recruiting
Surgery for a neck bone dislocation that can’t be put back
This study looks at surgical treatment for a specific type of neck bone dislocation that cannot be corrected without surgery. It may help patients whose imaging and traction testing show they need an operation to stabilize the neck.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04064671Recruiting
Study of a specific erectile implant after sex reassignment surgery
This study looks at surgical outcomes after placing the Zephyr ZSI 475 FTM inflatable penile implant in people who had female-to-male (transmasculine) sex reassignment surgery. It may help improve how well this specific implant works and how patients do after surgery.
Ghent, Oost-VlaanderenAges 18–100 - NCT05339789Recruiting
Annual follow-up after surgery for implant gum disease
This trial follows people who had surgery for gum inflammation around a dental implant and checks their results over the long term. It may help by improving how clinicians monitor healing and prevent implant problems after surgery.
ViennaAges 18–130 - NCT07128199RecruitingPhase 3
Zipalertinib after surgery for early-stage lung cancer with uncommon EGFR mutations
This study tests whether taking zipalertinib after lung cancer surgery can help prevent the cancer from coming back in people whose tumors have uncommon EGFR gene changes. It is a pill taken daily after recovery from surgery.
Anchorage, AlaskaAges 18 years+ - NCT06255197Recruiting
Study of lung cancer surgery patients and their outcomes
This study looks at the characteristics, treatments, and results of people who have had surgery to remove lung cancer. It aims to help doctors understand what happens after surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07872670Recruiting
Virtual reality to help recovery after hip or knee replacement
This study uses virtual reality (a computer-generated 3D environment you wear a headset for) alongside your usual care to help with recovery after hip or knee replacement surgery. It may help reduce pain or improve how well you move after surgery.
Inverness, HighlandsAges 18 years+ - NCT04810871Recruiting
Surgery for brain tumors that may come back
This study tests whether removing a brain tumor early, before it shows signs of growing back, can help prevent a recurrence. If you have had treatment before and there is still some tumor left, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT07860177Enrolling by invitation
Managing non-emergency blockages from scar tissue
This study tests a conservative approach for adults with a small bowel blockage caused by old scar tissue (adhesions). It avoids urgent surgery and lets the bowels rest to recover. The trial aims to find better ways to manage these blockages.
Florence, FIAges 18 years+ - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT06281210Recruiting
Test to skip breast surgery after chemo
This trial checks if a breast biopsy can confirm that chemo has destroyed all cancer cells, so you might avoid surgery altogether. It's for people with aggressive breast cancer types who responded well to chemotherapy.
Candiolo, TurinAges 18 years+ - NCT05701514Recruiting
Test in babies with a prenatal lung cyst found on scans
This trial is for newborns who are found before birth to have a congenital lung cyst (CPAM) and who stay symptom-free. It tests an approach for babies with certain CPAM features to see if it’s safer and/or more effective than standard care.
Nijmegen, GelderlanfAges 1 month–1 year - NCT04455282Recruiting
Blood test-guided surgery for gastroesophageal cancer
This trial studies blood-based biomarkers to help doctors choose the best individualized surgical treatment for gastroesophageal junction adenocarcinoma. If you qualify, you’ll get standard care plus additional testing to see whether the blood results can guide surgery more precisely.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT06268262Recruiting
Obesity brain imaging study before and after surgery
This study uses brain scans to understand how obesity affects the brain and how bariatric surgery may change it. It compares people with obesity who are planning surgery to healthy volunteers.
Xuzhou, JiangsuAges 18–65 - NCT05677152RecruitingPhase 2
Anti-bone-drug test to help shoulder tendon healing after surgery
This Phase 2 trial studies whether an anti-osteoporosis medicine (zoledronic acid) can improve healing after surgery for a chronic rotator cuff tear in the shoulder. If you qualify, you would also follow a specific 4-week physical therapy plan using a shoulder support pad.
ViennaAges 50–70 - NCT05389410Recruiting
PICO dressings compared during repeat hip or knee surgery
This study compares two types of wound dressings (PICO 7 vs PICO 14) in people having a repeat (revision) hip or knee operation. It aims to see which dressing works better to help the surgical wound heal after surgery.
Oswestry, ShropshireAges 18 years+ - NCT05098119RecruitingPhase 2
Study drugs before surgery for mouth or throat cancer
This Phase 2 trial tests giving the immunotherapy drug sintilimab before surgery, along with fewer chemotherapy cycles. The goal is to shrink or control oral or throat squamous cell cancers while keeping side effects lower, before the tumor is removed.
Guangzhou, GuangdongAges 18–80 - NCT05984810RecruitingPhase 2
Using a glowing dye to help see pancreatic cancer during surgery
This trial tests whether a special dye (SGM-101) can help surgeons see remaining cancer cells during surgery for pancreatic cancer that has been treated before surgery. It may lead to more complete removal of the tumor.
LeidenAges 18 years+ - NCT02897700RecruitingPhase 1
Testing chemotherapy choices for early breast cancer after surgery
This Phase 1 study tests different chemotherapy approaches in people with breast cancer that has been surgically removed but is early stage. It aims to find a chemotherapy plan that’s safe and works well right after surgery.
Ganzhou, JiangxiAges 18 years+ - NCT06366828Recruiting
Predicting complications after esophageal cancer treatment
This study looks at past medical records of people with esophageal cancer who received chemotherapy and radiation before surgery. Researchers want to find better ways to predict who might have complications after surgery, so they can improve care for future patients.
Nijmegen, GelderlandAges 18–100 - NCT06354738Recruiting
Endometrial cancer study with genetic and surgical insights
This study looks at combining genetic testing with surgical exams to better understand endometrial cancer. It may help doctors see which treatments could work best for you.
LeuvenAges 18 years+
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.