Clinical trials
T Cells clinical trials
Below are recruiting t cells clinical trials, each written for real people, not researchers. We’re tracking 5,686 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03311503RecruitingPhase 1/Phase 2
Gene therapy for X-linked SCID in young children
This trial tests a gene therapy using a lentivirus to give missing immune system instructions in children with X-linked SCID (SCID-X1). It also uses a low dose of targeted chemotherapy (busulfan) to help the new genes work, and it requires long-term follow-up for safety.
Los Angeles, CaliforniaAges birth–5 years - NCT03333200Recruiting
Study of genetic brain diseases over time
This trial follows people with genetic neurodegenerative (brain-wasting) disorders over time to better understand how the condition changes. The goal is to learn patterns that could help future treatments or care plans.
Pittsburgh, PennsylvaniaAges Any age - NCT03370406RecruitingPhase 1
Test cream and injection treatment for skin squamous cell cancer
This early-phase study tests whether combining an injection into the skin lesion with a topical cream can treat squamous cell skin cancer. It may help shrink the cancer and improve control in people whose tumor is in the lower legs or feet.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03382158Recruiting
Learn about DICER1-related tumors through a patient registry
This registry collects information about people with known or suspected DICER1-related conditions, including certain rare chest and other tumor types. It helps doctors and researchers understand these conditions better and may support future studies.
Minneapolis, MinnesotaAges birth–100 years - NCT03383978RecruitingPhase 1
Test brain injections plus IV antibody for HER2-positive glioblastoma
This early-phase study tests a combination of cells injected directly into the brain and an IV antibody to treat recurrent HER2-positive glioblastoma (or a related tumor, gliosarcoma). It may help by attacking the tumor locally in the brain while the antibody boosts the immune system’s response.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT03383575RecruitingPhase 2
Azacitidine plus enasidenib for IDH2-mutant MDS
This trial tests whether combining azacitidine with enasidenib helps people with myelodysplastic syndrome (MDS) that has an IDH2 mutation. It’s designed for people who are either new to “hypomethylating” treatment or whose MDS returned/worsened after it.
Baltimore, MarylandAges 12 years+ - NCT03384108Recruiting
Study of how certain immune cells use a nutrient
This study looks at how bone marrow plasma cells (a type of immune cell) use the nutrient glutamine. It may help researchers better understand what fuels these cells, which could guide future treatments.
Rochester, MinnesotaAges 18–60 - NCT03392233RecruitingPhase 2
Targeted radiation for spinal metastases causing significant pain
This trial tests a focused form of radiation (stereotactic body radiation) to treat cancer spread to the spine, especially when it causes substantial pain. It may help shrink or control the spinal spots while limiting damage to surrounding tissues.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT03403699Recruiting
Stem cell treatment for damaged eye blood vessels in diabetes
This study tests human iPSC–derived (lab-grown) cells aimed at repairing fragile, damaged blood vessels in diabetic retinopathy. It also involves eye exams and a small skin biopsy to support the research.
Birmingham, AlabamaAges 21–98 - NCT03500731RecruitingPhase 1/Phase 2
Lung and bone marrow transplant for lung and blood failure
This Phase 1/2 study tests a special lung-and-bone-marrow transplant approach for people with severe lung disease and bone marrow failure (low blood counts). The goal is to see if the treatment is safe and whether it can improve outcomes when standard long-term immune-suppressing medicines are a poor fit.
Pittsburgh, PennsylvaniaAges 18–60 - NCT03509961RecruitingPhase 2
Reducing total body radiation for children with leukemia transplants
This study looks at whether some children and young adults with B-ALL can safely get a transplant without total body irradiation (TBI), based on special leukemia test results. It’s meant to help lower radiation-related risks while keeping leukemia control strong.
Birmingham, AlabamaAges 1–25 - NCT03538899RecruitingPhase 1/Phase 2
Gene therapy for children with an Artemis SCID immune problem
This early-phase study tests an “autologous” gene therapy, meaning they use the child’s own cells, adjusted with a working gene, to help restore immune function. It is for babies and children with Artemis-deficient SCID, aiming to improve T-cell immunity and reduce the need for lifelong infection risk management.
San Francisco, CaliforniaAges 2 months+ - NCT03579875RecruitingPhase 2
Testing an inherited bone marrow transplant approach for rare blood disorders
This Phase 2 study tests a special “T-cell depleted” transplant plan for people with inherited bone marrow failure disorders (Fanconi anemia or T-Beta-thalassemia—or “TBD”). It may help restore healthy blood production while lowering the chance of certain transplant complications.
Minneapolis, MinnesotaAges Up to 65 years - NCT03581773RecruitingPhase 2
Folic acid to reduce mouth sores during kidney cancer treatment
This Phase 2 trial tests whether folic acid can lessen mucositis (painful mouth sores) caused by certain kidney cancer medicines. You would either take folic acid or an inactive pill, and the study looks for improvement in these side effects.
Aarhus, Central Region of DenmarkAges 18 years+ - NCT03589729RecruitingPhase 2
Dexrazoxane to help protect the heart during blood-cancer chemo
This Phase 2 study tests dexrazoxane, a heart-protecting medicine, to reduce heart side effects from chemotherapy in people with certain blood cancers. If you qualify, you would receive dexrazoxane along with chemotherapy, and the team will monitor your heart function closely.
Houston, TexasAges 12 years+ - NCT03595917RecruitingPhase 1
New and hard-to-treat BCR-ABL leukemia drugs plus prednisone and blinatumomab
This Phase 1 study tests a combination of targeted cancer drugs with prednisone and blinatumomab in people with BCR-ABL–positive B-cell leukemia (B-ALL), or chronic myeloid leukemia (CML) in lymphoid blast crisis. It may help by attacking leukemia cells through multiple pathways, especially when standard intensive chemotherapy is not suitable.
Chicago, IllinoisAges 18 years+ - NCT03601286RecruitingPhase 1
Gene therapy for X-linked SCID using a modified virus
This early-stage study tests a one-time lentiviral gene therapy to help children with X-linked severe combined immunodeficiency (SCID-X1) make infection-fighting T cells. It may reduce the need for a matching donor transplant, but it requires long-term follow-up for safety over many years.
London, Greater LondonAges 2 months–5 years - NCT03608631RecruitingPhase 1/Phase 2
Exosome treatment for KRAS-mutated metastatic pancreatic cancer
This Phase 1/2 study tests an investigational treatment made from “exosomes” for people with metastatic pancreatic cancer that has a specific KRAS mutation (KRAS G12D). It aims to see if this treatment can control the cancer and is safe for patients whose cancer has grown or stayed the same after prior chemotherapy.
Houston, TexasAges 18 years+ - NCT03612310Recruiting
Study uses stem cells to model genetic diseases
This study looks at how to create laboratory models of genetic diseases using stem cells made from people’s cells. It may help researchers understand disease causes and how treatments could work, using genetic patients (and some non-patient controls).
Edinburgh, MidlothianAges 1–120 - NCT03616483Recruiting
Indiana Myeloma Registry for blood cancer-related diagnoses
This registry collects information from adults with certain plasma-cell conditions like MGUS, smoldering multiple myeloma, multiple myeloma, plasmacytoma, or primary amyloidosis. It may help researchers learn more about these diseases and improve future care.
Indianapolis, IndianaAges 18 years+ - NCT03621241Recruiting
Blood test study to help diagnose myelodysplastic syndrome
This study checks whether a detailed blood-cell test can help diagnose myelodysplastic syndrome (MDS), a bone marrow condition that can cause low blood counts. Your results are compared with standard bone marrow testing to see how well the blood test performs.
AmiensAges 18 years+ - NCT03655015Recruiting
Using patient tumor cells to test lung cancer treatment response
This study looks at lung cancer samples you provide to see how tumor cells respond to treatment. It may help researchers find better ways to choose treatments for lung cancer by testing response in a lab model.
San Antonio, TexasAges 18 years+ - NCT03665675RecruitingEarly Phase 1
Immune cell treatment to control CMV or adenovirus after transplant
This early-phase study tests donor immune cells made to recognize CMV (a virus) or adenovirus, given to help control virus reactivation after a solid organ or bone marrow transplant. It may help reduce ongoing or worsening viral infection when standard antiviral medicines are hard to tolerate or not working well.
Columbus, OhioAges 1–85 - NCT03667599Recruiting
Home care program after your stem cell transplant
This study tests whether extra home-based medical support after a stem cell transplant can help patients during recovery. If you’re eligible, a trained care team will support you at home so you’re safer and better managed after discharge.
Durham, North CarolinaAges 18–80
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Common questions
- Are there clinical trials for t cells?
- Yes. Clin2 currently lists 5,686 recruiting t cells studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a t cells trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a t cells trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.