Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06442566RecruitingPhase 1/Phase 2
Enhancing opioid therapy for chronic pain with buprenorphine, counseling, and brain stimulation
This study is testing whether adding a medication (buprenorphine), counseling, and a type of brain stimulation (TMS) can improve long-term opioid therapy for chronic pain. If you have been taking prescription opioids daily for at least 3 months and have extra risk factors for opioid-related problems, this trial may offer you new ways to manage pain and reduce risks.
Charleston, South CarolinaAges 18 years+ - NCT06450041RecruitingPhase 2
STING trial for high-risk neuroblastoma
This trial tests a combination of chemotherapy (temozolomide and irinotecan), natural killer cells (NK cells), and an antibody therapy (GD2 mAb) to see if it can help children and young adults with high-risk neuroblastoma that has not responded to treatment or has come back.
Los Angeles, CaliforniaAges 1–31 - NCT06455293RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin, a substance found in certain mushrooms, can help improve depression in people with Parkinson's disease. If you have Parkinson's and are feeling depressed, this treatment may offer a new option.
San Francisco, CaliforniaAges 40–80 - NCT06458036RecruitingPhase 2
Selpercatinib before radioactive iodine for RET-positive thyroid cancer
This study tests whether a targeted drug called selpercatinib, taken before radioactive iodine therapy, can help treat thyroid cancer in children and young adults who have a specific genetic change (RET fusion or mutation). The drug may make the cancer more sensitive to the radioactive iodine treatment that follows.
San Francisco, CaliforniaAges 2–25 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT06458335Recruiting
Treating opioid use and loneliness
This study tests a program to help people with opioid use disorder who also feel lonely. It aims to see if treating both together can improve your health and wellbeing.
Rochester, New YorkAges 18 years+ - NCT06450314RecruitingPhase 2
De-escalating treatment for advanced HER2-positive breast cancer
This trial tests whether it's safe to reduce or stop some cancer treatments for people whose advanced HER2-positive breast cancer has been well-controlled for at least 2 years and has no detectable cancer cells in blood tests.
RennesAges 18 years+ - NCT06451861RecruitingPhase 2
Testing a new drug combo for newly diagnosed AML
This trial tests a new combination of drugs (ABC-14) against the standard treatment for adults newly diagnosed with acute myeloid leukemia (AML) who haven't had intensive treatment yet. The goal is to see if the new combo works better and is safe.
Dongguan, GuangdongAges 18 years+ - NCT06455917RecruitingPhase 2
Personalized immune cell therapy for advanced lung cancer
This trial tests a personalized treatment using your own immune cells (called TILs) to fight advanced non-small cell lung cancer that has progressed after standard therapy. You would have surgery to collect a tumor sample, then receive your expanded immune cells back as an infusion.
Basel, Canton of Basel-CityAges 18 years+ - NCT06459141Recruiting
Blood Thinning During Bone Tumor Surgery
This study tests whether a technique that thins your blood during surgery can help people having bone tumor removal. It may reduce the need for blood transfusions.
Hangzhou, ZhejiangAges 18–75 - NCT05476263Recruiting
Negative pressure wound therapy for esophagus or rectum
This trial studies whether a device called Suprasorb CNPendo helps healing of certain full-thickness (through-and-through) injuries or wounds in the esophagus or rectum. It may be an option if your medical team is already considering negative pressure wound therapy for these specific problems.
BerlinAges 18 years+ - NCT06055257RecruitingPhase 3
Combination therapy for jaw bone damage after radiation
This trial tests a combination of hyperbaric oxygen therapy and a medication called PENTOCLO to treat osteoradionecrosis (bone damage) in the jaw after radiation treatment for cancer. It may help heal the exposed bone.
Toronto, OntarioAges Any age - NCT06091306Recruiting
Study of family therapy for teens with anorexia
This study looks at how families change during a special type of therapy called multifamily therapy (where several families meet together) for teens with anorexia nervosa. The goal is to understand what helps families improve, so doctors can make treatment better.
Paris, Île-de-France RegionAges 6 years+ - NCT06427798RecruitingPhase 1/Phase 2
Radioactive drug for previously treated gut or adrenal tumors
This trial tests a new radioactive drug, [212Pb]VMT-alpha-NET, that targets a receptor found on some tumor cells. It is for people with certain gut or adrenal gland tumors that have already been treated with a similar therapy but are still growing.
Bethesda, MarylandAges 18–120 - NCT06144736RecruitingPhase 2
Surgery for stage 2 seminoma testicular cancer trial
This trial is testing whether removing affected lymph nodes with surgery (RPLND) works well alone for seminoma testicular cancer that has spread to nearby nodes but is still relatively small. It is for patients who have not had extensive chemo or radiation.
DüsseldorfAges 18–99 - NCT06371040RecruitingPhase 1
CAR-T cell therapy for severe myasthenia gravis
This trial is testing a new type of cell therapy called CAR-T that targets two proteins (CD19 and BCMA) on certain immune cells. It aims to help people with severe myasthenia gravis that has not improved with standard treatments.
Xi'an, ShaanxiAges 18–80 - NCT06332404Recruiting
Sleep apnea nerve stimulation therapy registry
This study is tracking how well a nerve stimulation device works for people with obstructive sleep apnea who can't use a CPAP machine. The device, called Inspire, sends mild electrical pulses to help keep your airway open while you sleep.
Edegem, AntwerpAges 18–99 - NCT06430528Recruiting
Osilodrostat and steroid replacement for Cushing syndrome
This trial tests a new approach, called 'block-and-replace', for treating Cushing syndrome. You will take osilodrostat to lower high cortisol levels, along with a glucocorticoid (a steroid) to replace what your body needs. This study may help control the disease if surgery hasn't worked or isn't an option.
Ann Arbor, MichiganAges 18–75 - NCT06429956Recruiting
Combined online therapy for anxiety and depression
This trial tests a new type of therapy that combines different treatment methods for anxiety and depression. It is completely online, so you can join from home, and it aims to help you feel better by tailoring the therapy to your needs.
AarhusAges 18 years+ - NCT06437977RecruitingPhase 3
Pre-surgery treatment with radiation, immunotherapy, and chemo for stage II-III NSCLC
This trial tests whether combining radiation, an immunotherapy drug (toripalimab), and chemotherapy before surgery can help shrink tumors and improve outcomes in people with resectable stage II to III non-small cell lung cancer. It aims to see if this approach works better than standard chemotherapy alone.
ShanghaiAges 18–75 - NCT06435351RecruitingEarly Phase 1
Personalized vaccine for high-risk triple-negative breast cancer
This trial tests a personalized vaccine made from your own immune cells (dendritic cells) to help prevent your high-risk triple-negative breast cancer from coming back. It is for people who had significant tumor left after standard chemotherapy and surgery.
Tampa, FloridaAges 18 years+ - NCT06428045RecruitingPhase 1
STARLITE for hard-to-surgery high-grade brain tumors
This trial tests a new treatment called STARLITE for people with fast-growing brain tumors (high-grade gliomas) that cannot be safely removed with surgery. The treatment uses a laser to destroy the tumor from the inside. It may be a good option if you haven't had any prior treatment for this tumor.
Miami, FloridaAges 18 years+ - NCT06434350RecruitingPhase 1/Phase 2
Enfortumab vedotin and radiation for advanced bladder cancer
This trial tests a drug called enfortumab vedotin combined with radiation therapy for people with locally advanced bladder cancer that hasn't spread to distant organs. The goal is to see if this combination works better than radiation alone and helps control the cancer.
Houston, TexasAges 18 years+ - NCT06434324Recruiting
Saline rinse for lung infection treatment
This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,179 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.