Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05957367RecruitingPhase 1/Phase 2
Study drug for advanced GIST tumors with specific gene mutations
This early-phase study tests inlexisertib (a targeted cancer drug) combined with other anticancer treatments in adults with advanced GIST. It is mainly looking for safety and the best way to dose, and it may help tumors that have certain KIT or PDGFRA gene changes.
Los Angeles, CaliforniaAges 18 years+ - NCT05966467Recruiting
Patient registry for AQP4+ neuromyelitis optica on C5 inhibitors
This registry collects health and relapse information from adults with AQP4-positive NMOSD who are taking C5-blocking medicines to prevent long-term relapses. It helps researchers better understand treatment patterns and outcomes in real-world care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05117450Recruiting
Compare two dialysis membranes to adjust heparin use
This study compares two dialysis membranes while using a reduced “weaning” plan for the blood thinner heparin during hemodialysis. It aims to see which membrane works better and safely during routine chronic dialysis.
ReimsAges 18 years+ - NCT05931289RecruitingPhase 2
Therapy plus brain scans after a recent suicide crisis
This Phase 2 study tests suicide-safety treatments given after a recent suicidal crisis or suicide attempt. It may help by reducing risk and understanding brain changes with follow-up brain scan visits.
Boston, MassachusettsAges 18 years+ - NCT05925036RecruitingPhase 1
Cell therapy trial for pain from long-term pancreatitis
This Phase 1 study tests a new cell-based treatment to reduce pain caused by chronic pancreatitis. It’s designed mainly to check safety first, and it may help people with ongoing, opioid-stable pancreatic pain.
Charleston, South CarolinaAges 18–75 - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT05920356RecruitingPhase 3
Tested KRAS-targeted sotorasib plus chemo vs pembrolizumab plus chemo
This Phase 3 trial tests whether sotorasib plus standard chemotherapy works better than pembrolizumab (an immunotherapy) plus standard chemotherapy as first treatment for certain advanced lung cancers. It may help people whose tumors have a KRAS G12C mutation and that do not show PD-L1 on testing.
Santa Barbara, CaliforniaAges 18–100 - NCT05921162Enrolling by invitation
Long-term follow-up after a vision gene eye injection
This study checks how people who previously received a gene therapy eye injection (vMCO-I) are doing over the long term. It may help researchers understand long-lasting effects and safety.
Cuttack, OdishaAges 18 years+ - NCT05918523Recruiting
Long-term follow-up for people treated with REACT
This study checks long-term health outcomes in people who previously received a treatment called REACT for chronic kidney disease. It may help doctors understand how safe and effective REACT is over time.
Meridian, IdahoAges 30–80 - NCT05935384Recruiting
Blood tests to track response to cancer therapy
This study follows how cancer responds to standard (usual) treatment by using blood samples and de-identified health data. It may help researchers understand whether “liquid biopsy” blood testing can reflect how well therapy is working.
Skokie, IllinoisAges 18 years+ - NCT05919238RecruitingPhase 1
Padeliporfin treatment for non-removable pancreatic cancer
This Phase 1 study tests a new cancer treatment called padeliporfin given through a special catheter to treat pancreatic ductal adenocarcinoma that cannot be removed by surgery. It aims to see how safe the treatment is and whether it can help control the tumor in people who are not surgical candidates.
Duarte, CaliforniaAges 18 years+ - NCT05929612RecruitingPhase 2
Low-dose targeted radiation alone for marginal zone lymphoma
This Phase 2 study tests whether very low-dose radiation (adjusted based on how you respond) can treat marginal zone lymphoma without adding other medicines at first. It may help some people by reducing radiation exposure while still controlling the cancer.
Houston, TexasAges 18 years+ - NCT05917678Recruiting
Compare head-shape treatments for infants with flat spots
This study looks at whether repositioning and a custom head-shaping helmet help improve head shape in babies who have cranial deformation. You may be asked to follow standard care and have your baby monitored for changes over time.
Dallas, TexasAges 2 months–3 months - NCT05917145RecruitingPhase 1
Drug WSD0628 plus radiation for recurrent brain tumor
This Phase 1 trial tests a new cancer drug (WSD0628) given with radiation for people whose high-grade glioma has returned after prior treatment. The goal is to find a safe dose and see how well the treatment works in this situation.
Rochester, MinnesotaAges 18 years+ - NCT05917301Recruiting
Pre-surgery proton radiation for soft tissue sarcoma
This trial studies a shorter-course proton radiation plan given before surgery for certain soft tissue sarcomas. The goal is to treat the tumor locally while helping surgery be safer or more effective.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05933395RecruitingPhase 2
Targeted treatment for ER+ breast cancer after CDK4/6 therapy
This Phase 2 study tests a genetically guided treatment plan for ER-positive breast cancer that has progressed after CDK4/6 therapy. It may help by matching treatment to tumor genetic changes.
Lebanon, New HampshireAges 18 years+ - NCT05919108RecruitingPhase 2
Neratinib before surgery for HER2-mutated invasive lobular breast cancer
This Phase 2 trial tests neratinib given before surgery to treat stage I–III invasive lobular breast cancer that has a specific HER2 mutation and is hormone-receptor positive. It may help shrink the tumor and improve control of cancer before and after surgery.
Atlanta, GeorgiaAges 18 years+ - NCT05912387RecruitingEarly Phase 1
Testing statin treatment in primary sclerosing cholangitis
This early study looks at how a statin (cholesterol-lowering medicine) affects people with primary sclerosing cholangitis (PSC) by measuring changes using multiple types of health data. It may help researchers understand which people benefit and how PSC biology changes with treatment.
Stanford, CaliforniaAges 18–80 - NCT05929027Recruiting
At-home gaming and exercise after stroke
This study tests whether an at-home program using gaming and hand exercises can improve arm and hand movement after a recent stroke. It may help you practice more comfortably at home with regular remote check-ins.
Baltimore, MarylandAges 21 years+ - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05941741RecruitingPhase 3
Tested low-dose radiation plus cadonilimab for nasopharyngeal cancer
This Phase 3 trial studies whether adding low-dose radiation to cadonilimab (an immune therapy) can improve outcomes for people newly diagnosed with a specific type and stage of nasopharyngeal cancer. If you’re eligible, it may offer a new treatment approach and helps researchers confirm whether it works best.
Guangzhou, GuangdongAges 18–70 - NCT05938712RecruitingPhase 2
Kidney transplant trial using two diabetes medicines safely
This Phase 2 trial tests whether combining two diabetes medicines—an SGLT2 tablet and a GLP-1 shot (semaglutide)—can improve kidney outcomes and safety in people with a kidney transplant. It may help some recipients, but it also carefully checks for infection risk, diabetes complications, and pregnancy plans.
Toronto, OntarioAges 18 years+ - NCT03945162RecruitingPhase 2
Bladder cancer trial using light therapy in the bladder
This Phase 2 study tests a treatment called photodynamic therapy (PDT) placed directly into the bladder. It may help people whose non–muscle-invasive bladder cancer did not respond to BCG treatment or could not tolerate it.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,179 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.