Clinical trials
Thoracic Aortic Aneurysm clinical trials
Below are recruiting thoracic aortic aneurysm clinical trials, each written for real people, not researchers. We’re tracking 63 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT04524247Recruiting
Testing a custom stent graft for frail aortic aneurysms
This study looks at a specialized, customized stent graft to treat certain aneurysms (bulges) of the aorta in people who may be considered frail. It’s meant to see how well the device works and how safely it can be used in patients who fit specific aneurysm patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07734584Recruiting
Reducing air bubbles during aortic repair with carbon dioxide
This trial tests a special flushing method using carbon dioxide gas to prevent air bubbles from entering the bloodstream during a procedure to fix the main artery in the chest. This could help avoid strokes or other complications.
Bologna, ItalyAges 18 years+ - NCT07695545Recruiting
Lipid metabolism study in ascending aortic aneurysm
This study looks at how fat metabolism and cell energy centers (mitochondria) work in patients having surgery for an ascending aortic aneurysm. It aims to understand differences between people with bicuspid or tricuspid aortic valves.
DijonAges 18 years+ - NCT07668687Recruiting
Long-Term Study of Castor and Cratos Stents for Aortic Arch Repair
This study tracks how well two types of stents (Castor and Cratos) work for people who have had a repair of the main artery in the chest (the aortic arch). If you already received one of these stents during your procedure, the study will follow your recovery and any future aortic events.
HamburgAges 18 years+ - NCT04372563Recruiting
Check treatment for aortic enlargement with tricuspid valve
This trial studies how to treat an enlarged part of the ascending aorta in people who have a tricuspid aortic valve. It may help slow or manage the risk connected to aorta enlargement.
TomskAges 45–75 - NCT07564375Recruiting
Testing a new graft for thoracic aorta problems
This early feasibility study tests a new branched stent graft (MBA device) designed to treat problems in the upper part of the aorta (the main artery from your heart) that involve branches going to your arms and head. The device may help patients who are considered too risky for traditional surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07438327Recruiting
AI study to improve heart and aorta CT analysis
This trial uses artificial intelligence to better analyze CT scans of the aorta, the large artery that carries blood from your heart. If your CT scan shows the aorta is partly cut off or missing in the images, the AI will help measure the parts that are fully visible.
Chapel Hill, North CarolinaAges 22 years+ - NCT05777460Recruiting
Testing custom-made devices for the thoracic aorta
This trial looks at the longer-term results of custom-made devices placed in the thoracic aorta (the main blood vessel in the chest). It may help patients learn how well these tailored devices work over time.
Roma, RMAges 18 years+ - NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT06882967Recruiting
Aortic aneurysm stent trial for high-risk anatomy
This trial tests a new stenting approach for patients with large or fast-growing aneurysms in the lower part of the chest's main artery. It focuses on people whose aneurysm shape makes standard treatment tricky.
Roma, RMAges 18 years+ - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT07078383Recruiting
Study of the Rapidlink device for aorta repair
This trial tests a device called Rapidlink that helps repair blood vessels branching off the aorta during open heart surgery. It may be an option if you need open surgery to fix your thoracic aorta.
Los Angeles, CaliforniaAges 18 years+ - NCT06332911Recruiting
Shockwave balloon to help place aortic stent graft
This trial tests a special balloon that uses shock waves to crack calcium in the iliac arteries, making room for a larger aortic stent graft. It is for people with a bulging aorta (aneurysm) who also have heavily calcified or narrow iliac arteries that would otherwise prevent the graft from passing through.
Münich, BavariaAges 18 years+ - NCT05803564Recruiting
Stent placement study for a torn, bulging main artery
This trial tests a specialized stent (a small mesh tube) placed inside the chest and belly aorta to treat a thoracoabdominal aortic dissecting aneurysm. It may help prevent the artery from getting bigger or causing dangerous bleeding by supporting the weakened area from inside.
Beijing, Beijing MunicipalityAges 18–80 - NCT04197648Recruiting
Supervised exercise study for certain thoracic aneurysms
This study looks at whether a supervised exercise program is safe and helpful for people with a thoracic (chest) aortic aneurysm. You may be able to join if your aneurysm size fits their range and you can safely attend training visits.
Québec, QuebecAges 18 years+ - NCT06786754Enrolling by invitation
Skin cell study for Marfan syndrome and aortic aneurysms
This study looks at skin cells (fibroblasts) from people with Marfan syndrome or other genetic conditions that cause thoracic aortic aneurysms. The goal is to understand how these cells behave, which may help improve future treatments.
San Donato Milanese, MilanAges 18 years+ - NCT06658730Recruiting
A study to check long-term safety of a Gore thoracic stent graft
This registry study tracks patients who have or will receive a Gore thoracic stent graft to see how well the device performs over time. It helps doctors understand the device's long-term benefits and any possible complications.
Tucson, ArizonaAges 18 years+ - NCT06526676Recruiting
Custom stent grafts for aortic aneurysms in high-risk patients
This study tests custom-fitted stent grafts for patients with aortic aneurysms who are not good candidates for open surgery or standard stent grafts. The grafts are modified by the surgeon during the procedure to match your specific anatomy.
Los Angeles, CaliforniaAges 18 years+ - NCT06501872Recruiting
Custom stent-graft for large chest and belly aneurysms
This study tests a special stent-graft, custom-shaped by your doctor to fit your aneurysm while keeping blood flow to important organs like your kidneys and stomach. It's for people with large aneurysms in the chest and belly who cannot safely have open surgery.
Lebanon, New HampshireAges 50–95 - NCT06336213Recruiting
Using a blood test to guide antibiotics in aorta surgery
This trial checks if a blood test called presepsin can help doctors decide when to use antibiotics in patients having surgery on the chest's main artery (the thoracic aorta). It is for people with an aneurysm or tear in that artery.
Moscow, MoscowAges 18–75 - NCT04747626Recruiting
Stent-based repair for damaged upper aorta segments
This trial studies a specific surgical approach using branched stents to repair multiple damaged parts of the upper (thoracic) aorta. It may help people who need urgent or complex aortic repair and are expected to survive more than two years.
Cleveland, OhioAges 18 years+ - NCT02050113Recruiting
Custom endograft repair for complex aortic aneurysms
This trial tests custom-made and doctor-modified grafts to treat complex bulges in the aorta (the body’s main artery) or the part going into the pelvis. It may help people who cannot use standard approved devices or who need treatment urgently because waiting is unsafe.
Worcester, MassachusettsAges 18 years+
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Thoracic Aortic Aneurysm trials by city
Studies with a site in or near these metro areas.
Thoracic Aortic Aneurysm trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for thoracic aortic aneurysm?
- Yes. Clin2 currently lists 63 recruiting thoracic aortic aneurysm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic aortic aneurysm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic aortic aneurysm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.