Clinical trials
Thoracic Aortic Aneurysm clinical trials
Below are recruiting thoracic aortic aneurysm clinical trials, each written for real people, not researchers. We’re tracking 63 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT02050113Recruiting
Custom endograft repair for complex aortic aneurysms
This trial tests custom-made and doctor-modified grafts to treat complex bulges in the aorta (the body’s main artery) or the part going into the pelvis. It may help people who cannot use standard approved devices or who need treatment urgently because waiting is unsafe.
Worcester, MassachusettsAges 18 years+ - NCT01524211Recruiting
Stent grafts for treating aortic aneurysms and dissections
This trial studies a special stent-graft placed inside the aorta to treat aneurysms, penetrating ulcers, or chronic dissections. It aims to see how well these branch stent grafts fit and seal the problem area while reducing the need for open surgery.
Boca Raton, FloridaAges 18 years+ - NCT02043691Recruiting
Testing specialized grafts to repair complex aortic problems
This trial studies different custom and modified stent-grafts (tiny metal-reinforced tubes placed inside the aorta) to repair difficult aortic aneurysms and dissections. It aims to see which approach best fits your aortic shape and helps keep blood flowing safely.
Birmingham, AlabamaAges 18 years+ - NCT02089607Recruiting
Fenestrated or branched stent for large aortic tears or bulges
This study tests a special type of stent-graft (a tube with branch openings) to treat large or rapidly growing aneurysms and certain aortic dissections in the chest/abdomen or aortic arch. It aims to prevent the aneurysm from rupturing and to safely restore blood flow to key branch arteries.
Rochester, MinnesotaAges 18 years+ - NCT02323581Recruiting
Stent procedure for large aortic aneurysms with custom grafts
This trial studies a less invasive “through-the-blood-vessel” stent graft procedure for large aneurysms in the main aorta or the aortic arch. It may help reduce the risk of aneurysm rupture while avoiding open surgery for people at higher surgical risk.
New York, New YorkAges 18 years+ - NCT03142074Recruiting
Study of how tissue works in enlarged aortic vessels
This study looks at the tissue “structure and strength” in people with a bulging (aneurysm) in the upper part of the aorta, either before symptoms or during emergency surgery. Your tissue samples help researchers understand why these aneurysms happen and how they may behave over time.
Leuven, Vlaams BrabantAges 18 years+ - NCT02266719Enrolling by invitation
Fenestrated branched stents for complex aortic aneurysms and safety
This trial studies a specialized endovascular (through-the-vessel) repair using fenestrated and branched stents to treat complex aortic aneurysms and related dissections. It aims to track clinical outcomes and how much radiation exposure is used during the procedure to improve safety.
Atlanta, GeorgiaAges 18 years+ - NCT01654133Enrolling by invitation
Testing branched stent grafts’ effect on blood flow after aortic repair
This study evaluates how well branched stent grafts work after repairing certain large or fast-growing aortic aneurysms (bulges in the main artery). It also checks blood-flow and organ function—especially flow to organs—in the weeks and months after the procedure.
Chapel Hill, North CarolinaAges 18 years+ - NCT00583817Enrolling by invitation
Endovascular repair for thoracic aortic aneurysms and dissections
This study tests whether repairing an enlarged or tearing (dissection) thoracic aorta using a catheter-based procedure can be safer for people who are high-risk for open surgery. It uses specialized stent grafts placed through blood vessels to seal the problem and prevent complications.
Boston, MassachusettsAges 18 years+ - NCT07438327Recruiting
AI study to improve heart and aorta CT analysis
This trial uses artificial intelligence to better analyze CT scans of the aorta, the large artery that carries blood from your heart. If your CT scan shows the aorta is partly cut off or missing in the images, the AI will help measure the parts that are fully visible.
Chapel Hill, North CarolinaAges 22 years+ - NCT07668687Recruiting
Long-Term Study of Castor and Cratos Stents for Aortic Arch Repair
This study tracks how well two types of stents (Castor and Cratos) work for people who have had a repair of the main artery in the chest (the aortic arch). If you already received one of these stents during your procedure, the study will follow your recovery and any future aortic events.
HamburgAges 18 years+ - NCT06786754Enrolling by invitation
Skin cell study for Marfan syndrome and aortic aneurysms
This study looks at skin cells (fibroblasts) from people with Marfan syndrome or other genetic conditions that cause thoracic aortic aneurysms. The goal is to understand how these cells behave, which may help improve future treatments.
San Donato Milanese, MilanAges 18 years+ - NCT05800743Enrolling by invitation
Stent grafts for high-risk ascending aorta problems
This study tests a new stent graft placed through the groin/back to treat problems in the ascending aorta (and sometimes the arch), usually when open-heart surgery is considered too risky. Doctors will check whether the device is safe and works well over time, including imaging and a long follow-up.
Birmingham, AlabamaAges 18 years+ - NCT07049913Recruiting
Gore TBE trial for descending thoracic aorta conditions in Japan
This trial tests a device called the GORE TAG Thoracic Branch Endoprosthesis (TBE) for people with certain diseases in the descending part of the main artery in the chest. It's designed to treat conditions like aortic aneurysm, traumatic tears, or complex aortic dissections while keeping blood flow to a key artery in the left arm.
Osaka, SuitaAges Any age - NCT07330752Recruiting
First test of A3-Shield device for belly artery bulge
This trial tests a new device called the A3-Shield that is placed inside the belly's main artery to support a bulging area (aneurysm) and keep it from growing or bursting. It may be an option for patients whose aneurysm is large enough but not yet causing symptoms.
TashkentAges 18 years+ - NCT03703947Recruiting
Testing blood and imaging biomarkers in abdominal aneurysm patients
This study looks at blood and/or scan markers to better understand abdominal aortic aneurysms (AAA). It may help doctors predict risks and guide follow-up or treatment choices.
Rotterdam, South HollandAges 18 years+ - NCT07166133Recruiting
GORE TAG Thoracic Branch Endoprosthesis for Zone 0/1 Study
This study is checking how well the GORE TAG Thoracic Branch Endoprosthesis works for people who need a stent graft in a specific part of the aorta (Zone 0 or 1). It may help if you have an aneurysm or other condition requiring treatment in that area.
Scottsdale, ArizonaAges 18 years+ - NCT03746964Recruiting
MRI study of the heart’s aorta before planned surgery
This study uses a special MRI scan to measure how the ascending aorta (a large blood vessel) moves and behaves before planned surgery. It may help doctors better understand the mechanics of an aortic aneurysm and improve future surgical planning.
DijonAges 18 years+ - NCT07391293Recruiting
Genetic aortic diseases and heart risks observational study
This study looks at people with genetic aortic diseases to understand risk factors for heart complications. By joining, you help researchers learn more about these conditions and how to better manage them.
MilanAges 14–60 - NCT05479305Recruiting
Stent placement for thoracic aorta problems in urgent high-risk patients
This trial studies a new type of stent graft placed in the chest aorta (from the aortic arch into the descending part) to treat aneurysms or dissections in people who are too high-risk for open surgery. It may help by offering a faster, less invasive repair when waiting for a custom stent would be unsafe.
BrestAges 18 years+ - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07483177RecruitingPhase 1/Phase 2
Heart study for enlarged aorta
This trial tests a treatment to help people with a mildly enlarged ascending aorta. It aims to slow down growth and prevent future heart problems.
Rochester, MinnesotaAges 18 years+ - NCT07089576Recruiting
Study of the Arcevo LSA device for aortic arch repair
This trial tests a new device called Arcevo LSA to treat certain types of aortic arch problems, like dissections (tears) or aneurysms (bulges). It is for people who need open surgery, and the device helps fix the left subclavian artery area.
Birmingham, AlabamaAges 18–80
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Common questions
- Are there clinical trials for thoracic aortic aneurysm?
- Yes. Clin2 currently lists 63 recruiting thoracic aortic aneurysm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic aortic aneurysm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic aortic aneurysm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.