Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07455851RecruitingPhase 1/Phase 2
Studying a new drug combo for relapsed or refractory multiple myeloma
This trial tests whether REGN17372 plus linvoseltamab is safe for people with multiple myeloma that has come back or not responded to prior treatments. You may join if you have tried at least 3 other therapies.
Randwick, New South WalesAges 18 years+ - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90 - NCT07449338Recruiting
Study of accelerated brain stimulation for depression
This trial tests a faster version of a brain stimulation treatment called TMS for people with depression. The goal is to see how well it works and how tolerable it is.
GothenburgAges 18 years+ - NCT06800612Recruiting
Cancer drug therapy study for gynecologic or breast cancers
This study looks at how well different cancer drugs work for women with breast or gynecologic cancers. Researchers will review medical records to see how patients responded to treatment over time. If you have been treated for breast or gynecologic cancer since 2010, you may be eligible.
BolognaAges 18 years+ - NCT07445347Enrolling by invitation
Bevacizumab for severe HHT liver issues with high heart output
This study looks at how well the drug Bevacizumab works and how safe it is for people with HHT who have severe liver problems that cause their heart to pump too much blood. It aims to help doctors understand if this treatment can help manage these serious symptoms.
PoitiersAges 18 years+ - NCT07448740Recruiting
Stepwise milk protein introduction after failed challenge
This study looks at a gradual method of introducing heated milk proteins to children who previously had a reaction to unheated cow's milk. It aims to help build tolerance over time.
BonheidenAges 1–18 - NCT07451613RecruitingPhase 1/Phase 2
Stem cell therapy trial for Huntington's disease
This trial tests whether human neural stem cells are safe and tolerable for people with Huntington's disease. It involves a neurosurgical procedure to inject the cells into the brain, along with MRI scans and other monitoring.
Irvine, CaliforniaAges 18–65 - NCT07449572RecruitingPhase 1
Safety study of HT31-1 for healthy volunteers
This trial tests a new drug called HT31-1 to see if it's safe in healthy people. It looks at how the drug moves in your body and if it causes side effects. This is a first step before testing it in patients with ARDS (a serious lung condition).
Richmond, VirginiaAges 18–65 - NCT07448155RecruitingPhase 1
Testing a new drug in healthy volunteers
This study tests a new medicine (INCA033989) given as a shot or IV in healthy adults to see how the body processes it and if it's safe.
Tempe, ArizonaAges 18–55 - NCT06800729RecruitingPhase 1
Testing safety of TIX100 in healthy volunteers
This phase 1 study tests an experimental drug called TIX100 in healthy volunteers to check its safety and how the body processes it. The results will help determine if the drug can be studied in future trials for conditions like obesity or metabolic disorders.
Chula Vista, CaliforniaAges 18–70 - NCT07442097Recruiting
Safety of a nutritional supplement in healthy older adults
This study tests a nutritional supplement (N-acetyl-L-cysteine and glycine) to see if it is safe and well-tolerated in healthy older adults. It may help if you are looking for ways to support your health as you age.
Pune, MaharashtraAges 60–80 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07439120RecruitingEarly Phase 1
Testing a new radioactive drug for advanced solid tumors
This trial tests a new radioactive drug called 68Ga/177Lu-BRP-020063 in people with advanced solid tumors, especially bladder or breast cancer. The drug seeks out Nectin-4 on cancer cells, helping doctors see and potentially treat the tumors. The goal is to check that the drug is safe and tolerable.
ShanghaiAges 18 years+ - NCT05268237RecruitingPhase 1/Phase 2
Testing a diabetes pill under the tongue for type 2 diabetes
This early-phase study tests the safety and side effects of liraglutide taken under the tongue, and looks for early signs it improves blood sugar in people with type 2 diabetes. It may help people who want an alternative way to get this medication, but the main goal is to see how safe and tolerable it is.
Hong KongAges 18–65 - NCT07433335RecruitingPhase 1
First study of sr-878 for rheumatoid arthritis safety
This study tests a new investigational drug called SR-878 for people with rheumatoid arthritis. It aims to see if the drug is safe and tolerable. You may join if you are between 18 and 60, have RA for at least 3 months, and take a stable dose of methotrexate.
TbilisiAges 18–60 - NCT07427394RecruitingPhase 2
Camizestrant and atirmociclib for advanced breast cancer
This trial tests two experimental drugs—camizestrant and atirmociclib—for women with advanced ER-positive breast cancer that has worsened after prior treatment. The goal is to see if the combination is safe and tolerable.
St Louis, MissouriAges 18 years+ - NCT07430397RecruitingPhase 1
Safety study of CITY-FXI in people with clotting risk factors
This trial tests a new medicine called CITY-FXI to see if it is safe and well tolerated in people who are at higher risk of blood clots, including those with certain genetic mutations or a past blood clot. It helps doctors find the right dose for future studies.
LondonAges 18–65 - NCT07433556RecruitingPhase 1
Testing a new stomach acid drug in healthy adults
This phase 1 trial tests a new medicine called IY-828026 in healthy volunteers to see how safe it is and how the body processes it. It's a first step to find the right dose and check for side effects.
SeoulAges 19–50 - NCT07433192Recruiting
A study on luseogliflozin for type 2 diabetes
This trial is looking at how well a diabetes medicine called luseogliflozin works and how tolerable it is for people with type 2 diabetes. It includes patients who have already started taking the drug as part of their regular care.
AnapaAges 18 years+ - NCT07432022RecruitingPhase 1/Phase 2
EMB-07 combo for aggressive B-cell lymphoma
This trial tests a new combination treatment for people with aggressive B-cell non-Hodgkin lymphoma, including those with relapsed/refractory disease or newly diagnosed high-risk cases. It aims to see if EMB-07 combined with other drugs is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06801470RecruitingPhase 1
Testing the safety of CD-001 in advanced solid tumors
This early-phase trial tests a new drug (CD-001) for people with advanced solid tumors. It will check if the drug is safe, how the body handles it, and if it helps shrink tumors.
TianjinAges 18 years+ - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Peoria, ArizonaAges 18 years+ - NCT07419841RecruitingPhase 1
A study of CTX-10726 for certain advanced cancers
This trial tests a new drug called CTX-10726 in people with advanced kidney, liver, stomach, or uterine cancer that has not responded to standard treatments. The goal is to see if the drug is safe and tolerable.
Phoenix, ArizonaAges 18 years+ - NCT07419698RecruitingPhase 1
Safety study of JMT206 injection in healthy volunteers
This early-stage trial tests a new medicine called JMT206 in healthy people to see if it is safe and how the body handles it. Healthy volunteers, ages 18 to 60, are needed to help researchers learn about the drug's effects and how it moves through the body.
Beijing, Beijing MunicipalityAges 18–60
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.