Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07486115RecruitingPhase 1
Testing safety of BI 3814916 in healthy volunteers
This trial tests how safe and tolerable different doses of the study drug BI 3814916 are in healthy adults. It helps find the right dose for future studies.
EdegemAges 18–65 - NCT07486817RecruitingPhase 2
Testing zongertinib with chemo and immunotherapy for advanced lung cancer
This trial tests a new drug called zongertinib combined with chemotherapy, with or without pembrolizumab (an immunotherapy), for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene. The goal is to see how safe and well-tolerated the combination is.
St Leonards, New South WalesAges 18 years+ - NCT07484204RecruitingPhase 1
Study of a once-monthly injection for stable schizophrenia
This trial tests a long-acting injectable form of cariprazine (AX251 LAI) for people with stable schizophrenia. You would receive one injection and stay at the clinic for 7 days to see how your body handles it and how well you tolerate it.
AhmedabadAges 18–65 - NCT07485426Enrolling by invitation
Activity and pain management for teens with chronic pain
This study tests an online program to help teens manage chronic pain and improve daily functioning. It uses acceptance and commitment therapy (ACT) to build coping skills and reduce suffering.
Linköping, Östergötland CountyAges 13–19 - NCT06186414RecruitingPhase 1
SIM0237 with or without BCG for bladder cancer
This trial tests a new drug, SIM0237, alone or with BCG, for people with a type of bladder cancer called non-muscle invasive bladder cancer (NMIBC) that did not respond to BCG treatment. The goal is to see if it is safe and works against the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT06600022RecruitingPhase 1/Phase 2
Studying SCTB41 for advanced solid tumors
This trial tests a new drug called SCTB41 in people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and if it shrinks tumors.
Guangzhou, GuangdongAges 18 years+ - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT07477587RecruitingPhase 1
Comparing two myeloma treatments for new patients
This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.
Springdale, ArkansasAges 18 years+ - NCT07476586RecruitingPhase 1
Study of GenSci161 safety in healthy adults
This trial tests a new medicine called GenSci161 to see if it is safe and how the body handles it. It is for healthy volunteers aged 18 to 45 who are willing to follow study rules and use birth control.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT07478744RecruitingPhase 2
Study for generalized anxiety disorder with SYT-510
This trial tests a new medicine called SYT-510 for adults with generalized anxiety disorder who are not currently taking medication. It aims to see if the drug reduces anxiety and is safe.
LondonAges 18–55 - NCT07474545RecruitingPhase 1
Safety study of KL0011034 injection in healthy volunteers
This trial tests a new injection called KL0011034 to see if it is safe and how the body processes it. Healthy volunteers aged 18–45 who meet specific health and lifestyle criteria can join.
Changsha, HunanAges 18–45 - NCT07473726RecruitingPhase 1
Study of a new drug for advanced solid tumors
This trial tests an investigational drug (HLX48) in people with advanced or metastatic solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and how well it works.
North Ryde, New South WalesAges 18–75 - NCT07476183RecruitingPhase 1
Testing APR-2020 for RPS19-deficient Diamond-Blackfan Anemia
This trial is testing a new treatment called APR-2020 for children and young adults with a specific type of Diamond-Blackfan Anemia (caused by a change in the RPS19 gene). The goal is to see if this treatment is safe, tolerable, and can help reduce the need for blood transfusions.
Stanford, CaliforniaAges 2–25 - NCT07477119RecruitingPhase 4
Personalized linezolid dosing for drug-resistant TB treatment
This trial tests whether adjusting the dose of linezolid based on regular blood tests can help people with multidrug-resistant tuberculosis (MDR-TB) tolerate the medication better while on the BPaL or BPaL-M regimen. It aims to reduce side effects and improve treatment success.
ConakryAges 15 years+ - NCT06780410RecruitingPhase 3
Study of bempedoic acid for lowering cholesterol
This trial tests a drug called bempedoic acid to see if it can safely help lower cholesterol in adults. It may be an option if you have high cholesterol and need a different treatment.
BeijingAges 18 years+ - NCT05601726RecruitingPhase 1/Phase 2
Study of a new drug for hard-to-treat AML or high-risk MDS
This early study tests a new medicine (ABD-3001) to see if it’s safe and tolerable, how the body handles it, and whether it shows early signs of helping people with relapsed or hard-to-treat AML or high-risk MDS. It may be an option if standard treatments have already failed and you can’t receive a stem cell transplant.
Marseille, FranceAges 18 years+ - NCT06772415RecruitingPhase 1
Study of GenSci122 for advanced solid tumors
This trial tests an experimental pill called GenSci122 for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if the drug is safe and can help shrink tumors.
Beijing, Beijing MunicipalityAges 18–75 - NCT05936346Recruiting
Check safety of a Salvia extract dietary supplement
This trial tests whether a Salvia-based extract (taken like a dietary supplement) is safe and well-tolerated in generally healthy adults. It also checks whether people can follow the study diet and activity routines during the trial.
LuganoAges 55–65 - NCT07469085RecruitingPhase 1
Safety study of SV003 in healthy volunteers
This trial tests a new medication called SV003 in healthy people to see if it's safe and how the body processes it. You may be able to join if you are in good health and meet certain weight and lifestyle requirements.
ShanghaiAges 18–45 - NCT07467993RecruitingPhase 2
Testing GXV813 for hospitalized adults with schizophrenia
This trial tests a new drug, GXV813, to see if it helps reduce symptoms in people with schizophrenia who are currently hospitalized due to a sudden worsening of their condition. It compares the drug's safety and effect against a placebo over several weeks.
Bentonville, ArkansasAges 18–65 - NCT07465653RecruitingPhase 1
Study of HJB647 for heart failure with reduced pumping ability
This trial tests a new medicine, HJB647, in people with heart failure who have a weak heart pump. It aims to see if the drug is safe and well-tolerated. You may qualify if your heart's pumping ability is reduced and you are on a specific standard therapy.
Bradenton, FloridaAges 18–100 - NCT07470593Recruiting
Monitoring glucose to detect early pancreatic islet graft loss
This study uses a continuous glucose monitor (CGM) to watch for early signs that a transplanted pancreatic islet graft may be losing function. The goal is to catch problems sooner and help keep the transplant working well.
StrasbourgAges 18 years+ - NCT07459166RecruitingPhase 2
Testing a new drug for fentanyl overdose
This study tests a new drug, CS-1103, to see if it can safely help reverse the effects of fentanyl (a strong opioid) even after a naloxone block. Healthy volunteers who have used opioids before will be given fentanyl and then the study drug, while researchers monitor safety and how the drug works.
Glendale, CaliforniaAges 18–55
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.