Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 940 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07681076RecruitingPhase 4
KarXT safety study with anti-nausea meds in healthy volunteers
This trial checks if adding anti-nausea drugs to a new medication (KarXT) is safe for healthy people. It involves a 3-week stay in a research center so doctors can monitor you closely.
Los Alamitos, CaliforniaAges 18–65 - NCT07827014Recruiting
Protein shake study for healthy adults
This study tests a daily protein shake in two flavors to see how well people tolerate it and if it affects their well-being. You would drink it once a day for 15 days and answer some questionnaires.
Carlsbad, CaliforniaAges 21–65 - NCT07570654RecruitingPhase 2/Phase 3
Testing COMP360 for post-traumatic stress disorder
This study tests whether COMP360, a new treatment, can help people with PTSD feel better and cope with their symptoms. The research team will measure how safe it is and how well it works over time.
Miami, FloridaAges 18 years+ - NCT07827144RecruitingPhase 1
Testing a new drug for advanced solid tumors
This study tests a new drug, BI 4060107, in people with advanced solid tumors. It is a phase 1 trial to find a safe dose and see how well people tolerate it, potentially offering a new option when standard treatments have stopped working.
Irving, TexasAges 18 years+ - NCT07498335RecruitingPhase 3
Atrasentan for children with IgA nephropathy
This trial tests an experimental medicine called atrasentan for children aged 2 to under 18 with IgA nephropathy, a kidney disease. The study aims to see if the drug can help protect kidney function and reduce protein in the urine, with fewer side effects than current treatments.
Neptune City, New JerseyAges 2–18 - NCT07570979RecruitingPhase 1
Testing INR731 for Metastatic Prostate Cancer
This trial tests a new drug called INR731, given by mouth, for men with prostate cancer that has spread to other parts of the body. The study will check if the drug is safe and how well it works, either alone or combined with other prostate cancer medicines.
Boston, MassachusettsAges 18 years+ - NCT07682870RecruitingPhase 1/Phase 2
Study of VG2025 for advanced solid tumors
This trial tests a new drug, VG2025, given through a vein for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and if it can help shrink or control the tumors.
ShanghaiAges 18–75 - NCT07615985RecruitingPhase 1
Safety and Blood Levels of PMG1016 in Healthy Adults
This study tests a new experimental medicine called PMG1016 to see how safe it is and how it moves through the body in healthy volunteers. You'll receive a single dose and have your blood checked and heart monitored to make sure the medicine is well-tolerated.
Brisbane, QueenslandAges 18–55 - NCT07731139RecruitingPhase 1
Testing a new medicine for people with obesity
This study tests how different amounts of the study medicine PF-08642534 are tolerated and how they work in the body of people with obesity. It aims to find a safe dose for future studies.
Lake Forest, CaliforniaAges 18–70 - NCT07754474RecruitingPhase 1
Testing a new medicine for overweight or obesity
This study tests a new drug called BI 3034701 to see how well people tolerate different doses. It may help with weight loss and related health issues.
MannheimAges 18–74 - NCT07477587RecruitingPhase 1
Comparing two myeloma treatments for new patients
This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.
Springdale, ArkansasAges 18 years+ - NCT07673627RecruitingPhase 2
Testing empasiprubart for generalized myasthenia gravis
This trial tests a new drug called empasiprubart for people with generalized myasthenia gravis (gMG) who have a certain antibody (AChR-Ab). It is given as a monthly IV infusion (into a vein) and aims to improve muscle weakness and daily functioning.
Miami, FloridaAges 18 years+ - NCT07780383RecruitingPhase 1
Single-dose study for healthy adults and early Alzheimer's participants
This trial tests a new investigational drug, BMS-986446, given as a single dose to healthy volunteers and multiple doses to people with early Alzheimer's disease. It aims to understand how the drug moves in the body, its safety, and whether it triggers an immune response, which could help guide future treatment for Alzheimer's.
Anaheim, CaliforniaAges 18–80 - NCT07758985RecruitingPhase 1
Testing a pill's safety and effect on mosquitoes in healthy adults
This study tests a new pill called lotilaner for safety and how well it works to kill mosquitoes that carry malaria. It is for healthy adults in Mali and may help future malaria prevention efforts.
BamakoAges 18–55 - NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Adelaide, South AustraliaAges 18–80 - NCT07633470RecruitingPhase 4
Zunveyl for Alzheimer's disease symptoms and caregiver support
This study tests a medication called Zunveyl to see if it helps reduce behavioral and neuropsychiatric symptoms in people with mild-to-moderate Alzheimer's disease, and whether it reduces stress on family caregivers. You would need a confirmed Alzheimer's diagnosis supported by a blood test, and a dedicated caregiver who can attend visits and report on your symptoms.
Irvine, CaliforniaAges 50 years+ - NCT07726147RecruitingPhase 1
Testing a new allergy shot for Japanese cedar pollen
This trial tests a new allergy shot (ITI-9001) for people with Japanese cedar pollen allergy. It aims to see if the shot is safe and can reduce allergy symptoms. The study is for people who have not tried immunotherapy before.
Tokyo, Shinjuku-kuAges 18–65 - NCT07765706RecruitingPhase 1
Testing an investigational medicine in healthy volunteers
This study tests a new medicine called INS1033 in healthy people to see if it is safe and how the body handles it. It is an early-stage study and does not involve treating any disease.
Salt Lake City, UtahAges 18–50 - NCT07802964RecruitingPhase 1
Early study of HRS-4139 in healthy adults
This trial studies an investigational medicine called HRS-4139 in healthy adults. The purpose is to see how safe it is, how the body processes it, and how it affects the immune system.
Changsha, HunanAges 18–55 - NCT07842640RecruitingPhase 1
Injectable treatment for overweight and obesity
This study tests an injectable medication called ASC35 to see if it is safe and tolerable for people who are overweight or obese. It may help with weight management, though it is an early-stage trial focused on safety first.
Baltimore, MarylandAges 18–65 - NCT07681271RecruitingPhase 2
Testing Remibrutinib for papulopustular rosacea
This study tests an experimental drug called remibrutinib (taken as a pill) to see if it can safely reduce the redness and bumps caused by papulopustular rosacea. It is for people with moderate to severe symptoms who have not had success with other treatments.
El Paso, TexasAges 18 years+ - NCT07615426RecruitingPhase 1
Testing aticaprant with antipsychotic medication for schizophrenia
This study tests whether a new medication called aticaprant is safe and well-tolerated when added to your current antipsychotic medication for schizophrenia. The goal is to see if it could help improve symptoms without causing serious side effects.
Garden Grove, CaliforniaAges 18–55 - NCT07673120RecruitingPhase 1
Safety study of ABBV-313 in healthy adults
This study tests a new drug called ABBV-313 in healthy adults to see if it is safe and how the body handles it. You will receive either a single injection or infusion, or multiple doses, to help researchers understand its effects.
Anaheim, CaliforniaAges 18–55 - NCT07807865RecruitingPhase 3
Testing a new anxiety medication for safety
This study is testing a new medication for generalized anxiety disorder. It will check if the drug is safe and well-tolerated when taken alone or alongside your current anxiety treatment.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 940 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.