Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 952 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT07656727RecruitingPhase 2
A study of BGE-102 for obesity and heart risk
This trial tests an experimental drug called BGE-102 in people with obesity and signs of inflammation. It aims to see if the drug can help reduce body weight and improve heart health. Participants must be willing to keep a stable diet and exercise routine.
Chandler, ArizonaAges 18 years+ - NCT07660198RecruitingPhase 3
Pneumonia vaccine catch-up study for kids and teens
This trial tests a catch-up pneumococcal vaccine for children and adolescents who may have missed some doses. It aims to see how safe and effective the vaccine is in healthy kids aged 15 months to 17 years.
Birmingham, AlabamaAges 1.3 years–17 years - NCT07667322RecruitingPhase 1
Study of a new under-the-skin multiple sclerosis treatment
This trial tests a new way to give ocrelizumab, an approved MS treatment, as a shot under the skin instead of through an IV. It aims to see if it's safe and works well for people with relapsing or primary progressive MS.
Carlsbad, CaliforniaAges 18–65 - NCT07670234Recruiting
Dietary Supplements and Cancer Treatment
This study looks at how dietary supplements (like vitamins and herbs) affect cancer patients who are on treatment. It checks if supplements cause side effects, change how medications work, or interact with each other.
RabatAges 18 years+ - NCT07583342Enrolling by invitationPhase 4
RELiZORB for feeding problems in severe pancreatitis
This study tests whether a medication called RELiZORB can help adults with moderate to severe acute pancreatitis (sudden, severe pancreas inflammation) tolerate nutrition delivered through a feeding tube. If your body is struggling to accept enough nutrition during acute pancreatitis, this trial may help you receive adequate nutrition while you recover.
Bay Shore, New YorkAges 18 years+ - NCT07485426Enrolling by invitation
Activity and pain management for teens with chronic pain
This study tests an online program to help teens manage chronic pain and improve daily functioning. It uses acceptance and commitment therapy (ACT) to build coping skills and reduce suffering.
Linköping, Östergötland CountyAges 13–19 - NCT07445347Enrolling by invitation
Bevacizumab for severe HHT liver issues with high heart output
This study looks at how well the drug Bevacizumab works and how safe it is for people with HHT who have severe liver problems that cause their heart to pump too much blood. It aims to help doctors understand if this treatment can help manage these serious symptoms.
PoitiersAges 18 years+ - NCT07373717Enrolling by invitation
Comparing fluid tolerance tests in shock patients
This trial studies different ways to measure how much extra fluid your body can handle when you are in shock. The goal is to see which method works best and helps doctors make better decisions about fluid treatment.
Nanjing, JiangsuAges 18 years+ - NCT07371065Enrolling by invitationPhase 1
Testing a new drug's safety in healthy adults
This trial tests a new medicine called LY03021 in healthy volunteers to see how safe it is, how the body processes it, and if food changes its effects. It's for people who are generally healthy and not taking other medications.
ShanghaiAges 18–45 - NCT07330440Enrolling by invitationPhase 1
MRNA vaccine study for preventing genital herpes
This study tests a new mRNA vaccine designed to protect against herpes simplex virus type 2 (HSV-2), the virus that causes genital herpes. It is for healthy adults who have not had a genital herpes outbreak in the last 6 months.
BeijingAges 18–55 - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT07223138Enrolling by invitationPhase 3
Long-term safety study of sonelokimab for psoriatic arthritis
This study is for people who have already been in a previous trial of sonelokimab for psoriatic arthritis and want to continue treatment. It checks how safe and effective the medicine is over a longer time.
Avondale, ArizonaAges 18 years+ - NCT07222189Enrolling by invitationPhase 2
Long-term safety of an experimental drug for Crohn's or colitis
This study looks at the long-term safety and side effects of an investigational drug called balinatunfib in people with Crohn's disease or ulcerative colitis. It is for patients who have already completed a full year of treatment in a previous related study.
Gorna OryahovitsaAges 19–77 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07178327Enrolling by invitationPhase 1
LYN101 safety study in healthy adults and postmenopausal women
This trial tests a new drug called LYN101 to see if it is safe and how it works in healthy adults and in postmenopausal women with low bone mass. It may help strengthen bones in women at risk for osteoporosis.
Bengbu, AnhuiAges 18–70 - NCT07149454Enrolling by invitationPhase 1
Testing a new antibody to prevent tetanus
This trial tests a new medicine made from antibodies that target tetanus toxin. It may help protect people from tetanus without needing a vaccine.
Lanzhou, GansuAges 18–60 - NCT07098091Enrolling by invitationPhase 1
Testing the safety of YD0293 in healthy adults
This phase 1 study tests a new medicine called YD0293 in healthy volunteers to see if it is safe and how the body handles it. It helps find the right dose for future studies.
Suzhou, JiangsuAges 18–45 - NCT07014462Enrolling by invitationPhase 1
Venetoclax and dexamethasone for untreated AML
This trial tests a combination of two oral medicines (venetoclax and dexamethasone) for people with newly diagnosed AML who cannot have or choose not to have high-dose chemotherapy. The goal is to see if this gentler treatment is safe and tolerable.
Burlington, VermontAges 18 years+ - NCT07007637Enrolling by invitationPhase 3
Long-Term Safety and Effectiveness of Sonelokimab for Hidradenitis Suppurativa
This study offers long-term treatment with an investigational biologic, sonelokimab, for people with moderate to severe hidradenitis suppurativa who finished an earlier sonelokimab study. The goal is to see if sonelokimab remains safe and effective over time.
Birmingham, AlabamaAges 12 years+ - NCT06958640Enrolling by invitation
Da Qing offspring health study
This study looks at the health of children, grandchildren, and great-grandchildren of people who took part in a diabetes prevention study in Daqing, China. It aims to understand how their family history affects their health over time.
Beijing, Beijing MunicipalityAges Any age - NCT06942312Enrolling by invitation
Liver metabolism study in non-alcoholic fatty liver disease
This trial studies how the liver processes fat in people with non-alcoholic fatty liver disease (NAFLD). It uses MRI scans to look at liver metabolism, which may help doctors understand the disease better and find new treatments.
Helsinki, UusimaaAges 18–75 - NCT06864598Enrolling by invitation
New immune cells to help stem cell transplant success
This trial tests whether a special type of immune cell (called CD8 regulatory precursors) can help prevent the body from rejecting a stem cell transplant from a donor. It is for patients receiving a stem cell transplant from a related donor.
Beijing, Beijing MunicipalityAges 18–60 - NCT06846138Enrolling by invitation
Herbal supplement to help metformin work better and cause fewer side effects
This study tests a special herbal blend added to metformin to see if it helps reduce stomach problems and improves blood sugar control in people with type 2 diabetes. Researchers want to understand how the herbs affect the bacteria in your gut.
RigaAges 25–80
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 952 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.