Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06183268Recruiting
Proton therapy for head and neck cancer skin side effects
This study looks at how proton therapy affects skin in people with head and neck cancer. It aims to better understand and manage skin reactions during treatment.
Knoxville, TennesseeAges 18 years+ - NCT06197581Recruiting
Safety of Radiation with Modern Breast Cancer Drugs
This study checks if giving certain modern breast cancer drugs at the same time as radiation is safe. It's for women who need radiation and are also taking one of these drugs: capecitabine, a CDK4/6 inhibitor, a PARP inhibitor, immunotherapy, or a HER2 inhibitor.
Beijing, Beijing MunicipalityAges 18–70 - NCT06200259Recruiting
Reducing Bowel Side Effects in Prostate Cancer Proton Therapy
This study tests a way to reduce stomach and bowel side effects of proton therapy for prostate cancer. It uses special software to place the proton beam more carefully, which may protect nearby organs.
Knoxville, TennesseeAges 18 years+ - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT06215495Recruiting
New radiation target method for high-grade glioma
This study is testing a new way to target radiation for people with high-grade gliomas (aggressive brain tumors). The goal is to see if a more precise treatment plan can improve outcomes while keeping side effects low.
GuangzhouAges 18–65 - NCT06226441Recruiting
Aminoglycoside antibiotics for sepsis with low kidney function
This study tests how well aminoglycoside antibiotics work in people with sepsis who also have low kidney function. It may help find the best way to treat serious infections in patients with kidney problems.
Larissa, ThessalyAges 18 years+ - NCT06270667Recruiting
Exercise training for lymphoma survivors
This study tests whether a supervised exercise program can improve heart health in people who finished treatment for Hodgkin or aggressive non-Hodgkin lymphoma 2–5 years ago. The goal is to see if regular exercise helps your heart recover better after chemotherapy or chest radiation.
OsloAges 20–70 - NCT06311968RecruitingPhase 2
Proton radiation after surgery for thymus tumors
This trial tests a type of precise radiation called proton therapy after surgery for thymus tumors. It may help reduce the chance of the tumor coming back while limiting side effects to nearby organs.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06344208Recruiting
Predicting side effects in older adults with head and neck cancer
This trial studies how to predict side effects (toxicity) in older adults (70+) with advanced head and neck cancer. It tests standard treatments like radiation, chemoradiation, or radiation with cetuximab and aims to help doctors tailor care to reduce harm.
Milan, MilanAges 70–99 - NCT06358677RecruitingPhase 2
Tretinoin cream to prevent skin rash from EGFR drugs
This study tests whether a topical tretinoin cream can prevent the skin rash often caused by anti-EGFR drugs like panitumumab or cetuximab. It is for people with advanced solid tumors who are about to start one of these treatments.
Salt Lake City, UtahAges 18 years+ - NCT06365853RecruitingPhase 2
Study of eye safety during treatment with MIRV for recurrent ovarian cancer
This trial tests a targeted drug called mirvetuximab soravtansine (MIRV) for recurrent ovarian cancer that has high levels of a protein called FRα. The study focuses on monitoring and preventing eye-related side effects, which are common with this treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06382818Recruiting
Personalized breast radiation based on risk and side effects
This trial tests whether radiation therapy can be personalized based on your risk of the cancer coming back and your risk of side effects from radiation. Depending on those factors, you may receive a tailored radiation plan that could be more or less intense.
MontpellierAges 18 years+ - NCT06461780Recruiting
Needs and Quality of Life in Advanced Cancer on Immunotherapy
This study looks at the physical and emotional needs of people with advanced cancer who are receiving immunotherapy. It aims to understand how these needs affect quality of life.
TaipeiAges 18 years+ - NCT06462963Recruiting
Single vs multiple radiation doses for cancer spread
This trial compares a single, strong dose of radiation to multiple smaller doses for treating cancer that has spread to a few spots. It aims to see which approach causes fewer side effects.
AalstAges Any age - NCT06500975Recruiting
Long-Term Results After Vestibular Implant
This study checks how well a vestibular implant works over many years for people who already got one in earlier research at Johns Hopkins.
Baltimore, MarylandAges 22–90 - NCT06531681Recruiting
Precision radiotherapy with MRI-guided technology
This trial tests a new type of radiotherapy that uses MRI scans to guide the radiation beam more precisely. It aims to treat tumors while reducing damage to healthy tissue.
HaikouAges 18–75 - NCT06542159RecruitingPhase 2
Adaptive radiation for early-stage lung cancer or small metastases
This trial tests a more precise radiation technique (stereotactic body radiotherapy) for early-stage lung cancer or small lung tumors. It aims to reduce side effects by eliminating the usual safety margin around the tumor.
Guangzhou, GuangdongAges 18 years+ - NCT06546631Recruiting
Blood side effects of a chemotherapy for brain tumors
This study looks at why some people getting the chemotherapy drug temozolomide (TMZ) for high-grade brain tumors have serious blood side effects. If you are getting TMZ now or have had severe blood problems from it, your participation could help doctors predict and manage these risks better.
CorkAges 18 years+ - NCT06549062Recruiting
Paracetamol dosing in obese vs non-obese surgery patients
This trial studies how the body processes intravenous paracetamol (Tylenol) in people with and without obesity. It aims to find the right dose for safety and effectiveness during laparoscopic surgery.
Ghent, Oost-VlaanderenAges 18–70 - NCT06550141RecruitingPhase 2
Preventing side effects of CAR-T therapy for large B-cell lymphoma
This trial tests if the drug emapalumab can help prevent toxic side effects often caused by CAR-T cell therapy. It is for adults with certain types of large B-cell lymphoma that have not responded to or returned after initial treatment.
Boston, MassachusettsAges 18 years+ - NCT06621459Recruiting
Study of abemaciclib safety for breast cancer patients
This study looks at real-world safety and side effect management of abemaciclib combined with hormone therapy for patients with RH+, HER2- breast cancer. It aims to understand how well patients tolerate treatment outside of clinical trials.
BrestAges Any age - NCT06637345Recruiting
Mesothelioma radiotherapy side effect study (MESORTIBO)
This study looks for markers in the blood that can predict side effects in patients with pleural mesothelioma who receive high-dose radiation. If you've had chemotherapy and are getting or have gotten high-dose radiation to the whole chest, researchers want to see if they can identify who is at higher risk of side effects.
Aviano, PordenoneAges 18 years+ - NCT06640959Recruiting
Bowel health study for prostate cancer radiation
This study tests whether a daily drink can help reduce bowel side effects caused by radiation for prostate cancer. If you are about to start radiation for intermediate to high-risk prostate cancer, you may be able to join.
Manchester, Greater ManchesterAges 18 years+ - NCT06664528Recruiting
Heart health study for adults getting certain chemo
This study tracks the heart health of adults receiving chemotherapy that may affect the heart. It helps doctors understand how to better monitor and protect patients.
Rome, LazioAges 18 years+
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 216 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.