Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06315933Recruiting
Anesthesia and brain development in children with congenital scoliosis
This study looks at how anesthesia (medicine used to put children to sleep during surgery) may affect the brain development of children with congenital scoliosis. It will help doctors understand how to make anesthesia safer for children with this condition.
Beijing, Beijing MunicipalityAges 6–16 - NCT03751566Recruiting
Acupuncture to ease short-term side effects of head and neck radiation
This trial studies whether adding acupuncture to standard radiation care can reduce short-term side effects from radiation for head and neck tumors. You might qualify if you are having treatment with the goal of cure or after-surgery prevention and can reliably complete symptom/side-effect tracking.
BrnoAges 18 years+ - NCT05331066Recruiting
Tracking side effects from immunotherapy using multiple tests
This study looks at how side effects happen in people receiving immune checkpoint inhibitor immunotherapy for solid cancers. It uses multiple types of tests to better understand these toxicities and may help improve safety and care in the future.
Chelsea, LondonAges 18 years+ - NCT06200259Recruiting
Reducing Bowel Side Effects in Prostate Cancer Proton Therapy
This study tests a way to reduce stomach and bowel side effects of proton therapy for prostate cancer. It uses special software to place the proton beam more carefully, which may protect nearby organs.
Knoxville, TennesseeAges 18 years+ - NCT06159660Recruiting
Lung Imaging to Reduce Radiation Side Effects
This trial tests a new way to plan radiation therapy for lung cancer by using a special imaging technique (functional lung imaging) to see which parts of your lungs work best. The goal is to reduce damage to healthy lung tissue while still targeting the cancer.
St Leonards, New South WalesAges 18 years+ - NCT03418961RecruitingPhase 3
Study of heart-risk management for metastatic HER2 breast cancer
This trial follows people with metastatic HER2-positive breast cancer who are at higher risk for heart damage while on HER2-targeted therapy. Some participants are randomly assigned to different monitoring/heart-protection approaches to see what best helps keep the heart safe.
Anchorage, AlaskaAges 18 years+ - NCT06081517Recruiting
Study of fairness in genetic cancer testing
This study looks at how well precision medicine (treatments based on your tumor's genes) is used for people with cancer. Researchers want to see if there are differences in who gets this kind of testing and treatment, so they can make it more fair for everyone.
Indianapolis, IndianaAges 18 years+ - NCT06059586Recruiting
Pre-hab program for women getting pelvic radiation for cancer
This trial tests a pre-rehabilitation (pre-hab) program to help women stay stronger before and during pelvic radiation for certain cancers. The goal is to see if it improves quality of life and reduces treatment side effects.
Avon, IndianaAges 18 years+ - NCT06052683Recruiting
Comparing radiation side effects for low-risk prostate cancer
This trial compares two types of radiation therapy (SBRT and LDR brachytherapy) for men with low-risk or favorable intermediate-risk prostate cancer. The goal is to see which treatment causes fewer side effects.
Québec, QuebecAges 18 years+ - NCT05913999Enrolling by invitation
PET and heart scans during early chemotherapy
This trial studies how a specialized heart imaging test (PET/MPI) changes during the start of chemotherapy for cancer patients. It may help researchers understand whether this monitoring approach detects heart strain early and keeps patients safer during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05784428Recruiting
Comparing one versus multiple radiation treatments for cancer that has spread
This trial tests whether giving one strong dose of radiation is as good as several smaller doses for people with a small number of cancer spots that have spread. The goal is to find a treatment that is just as effective but more convenient and with fewer side effects.
Kelowna, British ColumbiaAges 18 years+ - NCT05643014Recruiting
Study of chemical exposure in firefighters’ urine
This observational study looks at how common environmental chemicals may build up in firefighters, measured with urine samples before and after exposure. It may help researchers understand potential health risks in this job—even though you won’t receive study medicine.
Minneapolis, MinnesotaAges 18 years+ - NCT05639933RecruitingPhase 2
Topical cream for EGFR inhibitor skin rash in cancer patients
This Phase 2 study tests a topical cream (HT-001) to treat skin rashes caused by EGFR inhibitors. It aims to see whether the cream is safe and can reduce rash symptoms and discomfort.
Irvine, CaliforniaAges 18 years+ - NCT05394428Recruiting
Study sexual side effects after pelvic radiation in women
This study looks at sexual side effects after pelvic radiation for certain cancers of the female reproductive organs. It may help improve how these problems are understood and managed after treatment.
Atlanta, GeorgiaAges 18 years+ - NCT05354765Recruiting
Collect immune cells by lymphapheresis to study cancer response
This trial studies how changing your immune system (with earlier treatments) affects cancer by collecting immune cells from your blood using a process called lymphapheresis. It may help researchers find better ways to monitor immune-related responses and side effects.
ParisAges 18 years+ - NCT05301101Recruiting
Re-irradiation planning for tumors near previously treated organs
This study tests a more personalized way to plan “re-irradiation,” meaning giving radiation again in an area that was already treated before. It aims to better calculate organ risk to reduce harmful side effects while treating cancer.
Milwaukee, WisconsinAges 18 years+ - NCT05258422Enrolling by invitationPhase 2
Radiation ablation for recurring heart rhythm tachycardia
This study tests a targeted form of radiation therapy to stop a dangerous, repeat heart rhythm called ventricular tachycardia. It’s for people whose rhythm keeps coming back even after standard treatments like antiarrhythmic medications and prior heart procedure studies.
Montreal, QuebecAges 18 years+ - NCT05148156Recruiting
Urolift before radiation to reduce urinary side effects
This study tests whether a procedure called Urolift (which gently opens the prostate to relieve urinary blockage) before radiation therapy (SBRT) can reduce urinary side effects for men who have both prostate cancer and an enlarged prostate. If you qualify, you might experience fewer urinary problems during and after your cancer treatment.
Syosset, New YorkAges 50–99 - NCT05061342Recruiting
Cancer or healthy volunteers share health and imaging survey data
This study collects information about how cancer care affects daily life, treatment side effects, and quality of life, and it stores imaging and related data for future research. You might be able to take part if you’re scheduled for treatment at the center (or you’re a healthy volunteer) and can complete the questionnaires.
Shenzhen, GuangdongAges 18 years+ - NCT04871542Recruiting
Predicting risk of immune therapy side effects
This study tries to predict who is more likely to get serious side effects from immune checkpoint medicines used for solid tumors. You may help researchers by answering questionnaires before treatment and during follow-up, and by possibly storing sample specimens.
Anchorage, AlaskaAges 18 years+ - NCT04856488RecruitingPhase 3
Lugol’s iodine solution before thyroid surgery for overactive thyroid
This trial tests whether taking Lugol’s iodine solution before thyroid surgery is safe and helpful for people with Graves’ disease or toxic nodular goiter (overactive thyroid). It may be aimed at improving surgical readiness and outcomes by reducing thyroid activity before the operation.
Solna, Stockholm CountyAges 18–75 - NCT03894917Recruiting
Study blood and imaging features in older adults with liver cancer
This study looks at what liver cancer is like in newly diagnosed people who are older and whose cancer cannot be removed by surgery. It may help doctors better understand disease behavior and how treatments may work and affect the body.
San Antonio, TexasAges 18 years+ - NCT04615988Recruiting
Vitamin D levels and hormone side effects from immune cancer therapy
This study looks at whether your blood vitamin D level is linked to hormone-related side effects caused by immune checkpoint cancer drugs. It may help doctors better predict who is at risk and how to monitor patients during treatment.
New York, New YorkAges 18 years+ - NCT04638725Recruiting
Genetics study to find why HER2 breast cancer treatment varies
This study looks at genetic factors to understand why some people’s HER2-positive breast cancer responds better—or has more side effects—after treatment. Your info and possible past treatment history may help researchers improve how HER2 treatment is chosen and managed.
StrasbourgAges 18 years+
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 208 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.