Clinical trials
Transcatheter Valve Replacement clinical trials
Below are recruiting transcatheter valve replacement clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03836521Recruiting
Registry for valve replacement in bicuspid aortic stenosis patients
This registry collects information about adults with severe narrowing of the aortic valve caused by a bicuspid (two-leaflet) valve shape, especially if symptoms are present. It may help doctors better understand who benefits from a catheter-based valve replacement (TAVR).
Los Angeles, CaliforniaAges 19–129 - NCT04454177Recruiting
Smartwatch help to discharge earlier after valve replacement
This study tests whether using a smartwatch can safely help people leave the hospital earlier after a transcatheter aortic valve replacement (TAVR). It checks comfort, safety, and follow-up at home.
Hangzhou, ZhejiangAges 18 years+ - NCT04914468Recruiting
Study registry for mitral valve replacement by catheter
This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.
HamburgAges 18–110 - NCT04954404Recruiting
Mitral valve procedure registry for Chinese patients in one center
This study is a registry (a way to track real-world outcomes) for people with mitral valve disease who receive a mitral valve procedure. It helps doctors understand how well these procedures work and what complications happen in patients like you.
Hangzhou, ZhejiangAges 18 years+ - NCT02803294RecruitingPhase 4
Study of heart valve replacement outcomes in Chinese patients
This study records results of a minimally invasive procedure to replace a narrowed or leaking heart valve. It may help doctors understand how well the treatment works and what complications happen in Chinese patients.
Hanzhou, ZhejiangAges 18 years+ - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT01737528Recruiting
Transcatheter heart valve therapy registry for adults
This registry collects information from adults who receive a less invasive heart valve procedure (done through a catheter). The goal is to learn how these treatments work in real-world patients and care over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05778773Recruiting
Study of treatment outcomes for severe aortic valve narrowing
This study looks at how well current treatment choices work for older adults with severe aortic valve narrowing (stenosis). It may help doctors better understand what works best for aging patients in Italy.
San Donato Milanese, MIAges 65 years+ - NCT05864456Recruiting
Study testing a new valve delivered through a blood vessel
This trial studies Prizvalve Pro™, a new transcatheter (catheter-based) aortic valve replacement, for people with severe aortic valve narrowing who are too high-risk for standard surgery. It may help your heart work better and improve symptoms by replacing the failing valve without open-heart surgery.
ShanghaiAges 65 years+ - NCT05310461Recruiting
Early or delayed valve surgery for mixed heart valve disease
This study compares doing aortic valve replacement sooner versus waiting, in people with moderate aortic valve narrowing plus at least moderate leakage in the mitral valve. It aims to see which timing improves heart symptoms and outcomes while keeping treatment safe.
BernAges 18 years+ - NCT05235555Recruiting
TAVI registry for people with severe aortic valve disease
This registry follows people with severe aortic valve narrowing (and sometimes a worn-out valve) who are considered good candidates for TAVI, a valve-replacement procedure. It helps doctors better understand outcomes and care over time.
NaplesAges 55–100 - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06381271Recruiting
TAVR for severe aortic valve regurgitation
This trial tests a procedure called TAVR to replace the aortic valve in people with severe aortic regurgitation (a leaky valve). It may help you if you have this condition and prefer a less invasive option than open-heart surgery.
Xi'an, ShannxiAges 18 years+ - NCT07709858Recruiting
Outcomes after TAVR for severe aortic valve disease
This is a registry study that tracks how people do after a TAVR procedure for a severely narrowed aortic heart valve. It helps doctors learn more about long-term outcomes and improve care for future patients.
SeoulAges 18 years+ - NCT06722066Recruiting
TAVR and heart valve calcium study
This study looks at how calcium buildup in the aortic valve affects long-term results after a TAVR procedure (a minimally invasive heart valve replacement). It may help doctors understand which patients do better over time.
SeoulAges 19 years+ - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT06493994Recruiting
Looking at Myval valve placed through the armpit
This study collects information on people who have already received a new aortic valve through a small cut in their armpit using the Myval valve. Doctors want to see how well this approach works over time.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT07516145Recruiting
Robotic catheter repair for leaky tricuspid heart valve
This trial tests a new robotic catheter procedure to repair a leaky tricuspid valve (the valve on the right side of your heart). Instead of open-heart surgery, doctors thread a tiny device through a vein in your neck to fix the valve. It may be an option if you have severe leaking and your heart team thinks surgery is too risky for you.
ShatinAges 18–90 - NCT07511673Recruiting
Dental screening before heart valve surgery
This trial tests whether a dental checkup before heart valve surgery can improve recovery and prevent complications. If you are scheduled for a heart valve procedure, you may be able to join.
GothenburgAges 18 years+ - NCT07462624Recruiting
Comparing treatments for a failing surgical aortic valve
This trial compares two ways to treat a failing aortic valve that was replaced with a tissue valve during surgery: another surgical replacement or a less invasive catheter-based valve-in-valve procedure. It is for people with low to intermediate surgical risk who are between 18 and 75 years old.
Leipzig, SaxonyAges 18–75 - NCT07455292Recruiting
Heart valve study using advanced MRI
This study uses a special type of MRI, called 4D flow MRI, to better understand how severe aortic stenosis (a narrowed heart valve) affects heart function. It may help doctors learn more about different types of this condition and improve future treatment.
San Donato MilaneseAges 18 years+ - NCT05739253Recruiting
Study how the aorta changes after a valve procedure
This trial looks at how the ascending aorta (the main artery near the heart) changes over time after transcatheter aortic valve replacement. It may help doctors predict who is at risk of aorta enlargement after this less-invasive valve procedure.
Beijing, Beijing MunicipalityAges Any age
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Common questions
- Are there clinical trials for transcatheter valve replacement?
- Yes. Clin2 currently lists 132 recruiting transcatheter valve replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transcatheter valve replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transcatheter valve replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.