Clinical trials
Transcatheter Valve Replacement clinical trials
Below are recruiting transcatheter valve replacement clinical trials, each written for real people, not researchers. We’re tracking 136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05797519Recruiting
Transcatheter valve replacement for leaking tricuspid valve
This trial studies a catheter-based procedure to replace the tricuspid valve in people with severe valve leakage. It aims to improve symptoms and heart function while tracking safety and effectiveness.
Sydney, New South WalesAges 18 years+ - NCT05848284Recruiting
Tricuspid valve replacement to reduce leaking in the heart
This trial tests a new catheter-based procedure that replaces the tricuspid valve to reduce severe valve leaking. It may help people who still have symptoms despite heart medicines, but only if their heart shape and other health details fit the device requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05864456Recruiting
Study testing a new valve delivered through a blood vessel
This trial studies Prizvalve Pro™, a new transcatheter (catheter-based) aortic valve replacement, for people with severe aortic valve narrowing who are too high-risk for standard surgery. It may help your heart work better and improve symptoms by replacing the failing valve without open-heart surgery.
ShanghaiAges 65 years+ - NCT06000943Recruiting
Bleeding and clot risk after heart valve procedure
This study looks at patients who had a TAVR procedure (a new valve put in the heart) to understand their risk of bleeding or clots over the next year. It tracks changes in blood thinner medications at 1 month, 90 days, and 1 year to help doctors personalize care.
AalstAges 18 years+ - NCT06033274Recruiting
Global registry for tricuspid valve replacement
This study is a registry that collects data on patients who receive a new type of heart valve replacement for the tricuspid valve through a less invasive catheter procedure. Joining helps doctors learn more about how well this treatment works in real-world patients.
Phoenix, ArizonaAges 18 years+ - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06381271Recruiting
TAVR for severe aortic valve regurgitation
This trial tests a procedure called TAVR to replace the aortic valve in people with severe aortic regurgitation (a leaky valve). It may help you if you have this condition and prefer a less invasive option than open-heart surgery.
Xi'an, ShannxiAges 18 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06420830Recruiting
Study of a new heart valve in TAVR
This study follows patients with severe aortic stenosis who get a new heart valve (the SAPIEN 3 Ultra RESILIA) through a less invasive procedure (TAVR). Researchers want to see how well this valve works over time using special heart ultrasound tests.
Québec, QuebecAges 18–80 - NCT06472934Recruiting
Beta-blockers & TAVR study
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
GrazAges 18 years+ - NCT06493994Recruiting
Looking at Myval valve placed through the armpit
This study collects information on people who have already received a new aortic valve through a small cut in their armpit using the Myval valve. Doctors want to see how well this approach works over time.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT06557798Recruiting
Second TAVI for failing aortic valve replacement
This trial is for people who have already had a TAVI (a minimally invasive aortic valve replacement) and now need a second procedure because the valve is failing. The study will test how well a redo TAVI works to fix the failing valve.
AalborgAges 18 years+ - NCT06569602Recruiting
EVOQUE valve study for leaky tricuspid valve
This study is testing a new way to replace the tricuspid valve (the valve that controls blood flow from the heart's right upper chamber to the right lower chamber) without open-heart surgery. The goal is to see how safe and effective the EVOQUE valve is for people with a leaky tricuspid valve.
Bad OeynhausenAges Any age - NCT06581471Recruiting
New device for severe leaky heart valve
This study tests a new device to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe leakage who are considered too high-risk for traditional surgery.
AalstAges 18 years+ - NCT06589063Recruiting
TAVR for severe low flow, low gradient aortic stenosis
This study tests whether TAVR (a minimally invasive valve replacement) helps people with a specific type of severe aortic stenosis where the heart doesn't pump as strongly. It aims to see if the procedure improves symptoms and outcomes.
SalernoAges 18 years+ - NCT06611579Recruiting
Study of the MonarQ System for Leaky Tricuspid Valve
This study tests a new device called the MonarQ TTVR System, which is placed through a small tube in a blood vessel to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe tricuspid regurgitation symptoms that are not relieved by heart failure medicines alone.
Los Angeles, CaliforniaAges 18 years+ - NCT06722066Recruiting
TAVR and heart valve calcium study
This study looks at how calcium buildup in the aortic valve affects long-term results after a TAVR procedure (a minimally invasive heart valve replacement). It may help doctors understand which patients do better over time.
SeoulAges 19 years+ - NCT06777368Recruiting
Redo TAVR for failed transcatheter aortic valves
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
Birmingham, AlabamaAges 18–105 - NCT06817148Recruiting
TAVR vs surgery for bicuspid aortic valve disease
This study compares two treatments for severe aortic stenosis in people with a bicuspid aortic valve: transcatheter aortic valve replacement (TAVR, a less invasive procedure) and surgical aortic valve replacement (SAVR, open-heart surgery). The goal is to see which approach works better for this specific condition.
Los Angeles, CaliforniaAges 50 years+ - NCT06818084RecruitingPhase 4
TAVR for severe aortic regurgitation using VitaFlow Liberty
This trial tests the VitaFlow Liberty device, a catheter-based treatment for people with severe aortic regurgitation (a leaky heart valve). If you have symptoms or your heart is starting to weaken, this procedure might help avoid open-heart surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06830499Recruiting
Sapien 3 valve for younger Chinese patients with severe aortic stenosis
This trial tests a newer artificial heart valve (Sapien 3) placed through a small tube in the leg, for younger people (50–70) with severe aortic stenosis. It aims to see if this less invasive option works well in this age group.
Xi'an, ShaanxiAges 50–70 - NCT06896227Recruiting
TAVR positioning and its effect on valve and heart blood flow
This study looks at how the placement of a new aortic valve (TAVR) affects blood flow through the valve and into the heart arteries. It may help doctors understand best practices for people who already had a TAVR procedure.
DüsseldorfAges Any age
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Common questions
- Are there clinical trials for transcatheter valve replacement?
- Yes. Clin2 currently lists 136 recruiting transcatheter valve replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transcatheter valve replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transcatheter valve replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.