Clinical trials
Transplant clinical trials
Below are recruiting transplant clinical trials, each written for real people, not researchers. We’re tracking 1,497 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+ - NCT04924270RecruitingPhase 2
Capsule stool transfer for newly diagnosed inflammatory bowel or joint disease
This Phase 2 study tests whether taking capsule stool (FMT) is safe and can help people who are newly diagnosed and haven’t started the usual medicines yet. Participants will also start the standard first-line treatment for their condition, and the study will compare safety and outcomes.
OdenseAges 18–75 - NCT05735717RecruitingPhase 2
T-cell transplant using depleted receptors for blood cancers
This Phase 2 study tests a specialized stem cell transplant that removes certain immune “T-cell” receptors to help treat blood cancers like acute leukemia. It may help your body rebuild a healthier immune system after high-dose treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT04792489RecruitingPhase 2
CAR-T cell therapy for aggressive B-cell lymphomas
This trial tests a new CAR-T cell treatment (MB-CART2019.1) for people with certain types of aggressive B-cell non-Hodgkin lymphoma, including diffuse large B-cell lymphoma (DLBCL) that has come back or not responded to prior treatments. It aims to see if this therapy can help when other options have failed.
Birmingham, AlabamaAges 18 years+ - NCT07230886Recruiting
Reducing transplant complications with enhanced preservation
This trial tests a new way to preserve donated lungs before transplant to lower the risk of complications. It may help primary graft dysfunction, a serious lung problem after surgery.
Toronto, OntarioAges 17 years+ - NCT07599176RecruitingPhase 1/Phase 2
Partial stem cell transplant for sickle cell disease from matched donors
This study tests a partial stem cell transplant from a matched donor to treat sickle cell disease. It may help reduce complications like strokes, organ damage, or pain crises.
Bethesda, MarylandAges 4–65 - NCT04970446RecruitingPhase 1/Phase 2
Fecal transplant to restore gut microbes in Crohn’s
This Phase 1/2 study tests whether a fecal microbiome transplant (FMT) can reduce active inflammation in people with Crohn’s disease. It’s designed for people who currently have signs of active bowel inflammation and can attend regular procedure visits.
Melbourne, VictoriaAges 18–70 - NCT04989491RecruitingPhase 4
Single-dose rituximab to prevent EBV after kidney transplant
This trial tests whether one dose of rituximab (given around the time of transplant) can help prevent a first Epstein-Barr virus (EBV) infection and related abnormal lymph node or immune growths after kidney transplant. It is specifically for adults who are EBV-negative before receiving an EBV-positive donor kidney.
StrasbourgAges 18 years+ - NCT04991103RecruitingPhase 2
Testing delaying stem cell transplant after early myeloma response
This Phase 2 study tests whether people with newly diagnosed multiple myeloma can safely delay or avoid an immediate stem cell transplant if they respond well to early treatment. It aims to see if this “response-adapted” approach can still control the disease while reducing the need for upfront transplant for some patients.
Birmingham, AlabamaAges 18 years+ - NCT05029531RecruitingPhase 3
Immuno-chemotherapy for infants with B-lineage ALL
This trial tests a combination of medicines (immunotherapy plus chemotherapy) in babies diagnosed with a type of leukemia called B-lineage acute lymphoblastic leukemia (ALL). It aims to improve how well treatment works and is delivered safely in very young children.
Moscow, Samory-Mashela,1Ages 1 day–12 months - NCT05031897RecruitingPhase 2
Haplo transplant with reduced donor mismatch and radiation
This trial tests a special bone marrow/stem cell transplant approach using a partially matched family donor, along with conditioning treatment that involves radiation. It aims to help treat certain blood cancers by replacing damaged blood-forming cells with new ones from the donor.
Philadephia, PennsylvaniaAges 18 years+ - NCT05041140Recruiting
Xenon MRI test for lung problems after stem cell transplant
This study uses a special MRI test with xenon gas to look at lung function in adults who had a stem cell transplant and now have breathing-related complications. It may help doctors measure lung impairment more clearly and track changes over time.
Houston, TexasAges 18 years+ - NCT05066412RecruitingPhase 1
Preventing relapse after a half-matched transplant with modified donor cells
This early-phase study tests whether giving donor immune cells (DLI) that have been “depleted” of a specific marker (CD45RA) can lower the chance of the leukemia/lymphoma coming back after a half-matched stem cell transplant. It’s meant to be preventive, not treatment for an active relapse.
Geneva, Canton of GenevaAges 18 years+ - NCT05071222RecruitingPhase 1/Phase 2
Gene therapy trial for Artemis SCID using modified blood cells
This trial tests whether gene therapy can safely and effectively treat children with a specific type of severe combined immunodeficiency (SCID) caused by an Artemis gene problem. It uses the patient’s own stem cells, modifies them to add a missing gene, and then returns them after chemotherapy to help the new cells work.
ParisAges Up to 3.9 years - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT05091372RecruitingPhase 2
Maintenance treatment after transplant for newly diagnosed myeloma
This trial tests whether using belantamab mafodotin plus lenalidomide as long-term maintenance after an autologous stem cell transplant can keep multiple myeloma under control, guided by minimal residual disease (MRD). MRD is a very small amount of disease that may remain after transplant, and the study helps see if treating those patients better improves outcomes.
Houston, TexasAges 18 years+ - NCT05095532RecruitingPhase 1
TP-IAT transplant with your own cells for type 1 diabetes
This early-stage study tests whether adding your own special cells (mesenchymal stromal cells) at the same time as a TP-IAT transplant can improve diabetes outcomes. It may help people who are already planning TP-IAT, but it is only for certain age, diabetes, and health criteria.
Charleston, South CarolinaAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05170347Recruiting
Study of graft-versus-host disease after bone marrow transplant
This study follows people after an allogeneic bone marrow transplant to understand a complication called graft-versus-host disease. If you can attend follow-up visits, your experience and samples may be compared with a family control to look for differences.
Hong KongAges 18 years+ - NCT05180097RecruitingPhase 2
Immunotherapy with stem cell transplant for relapsed Hodgkin lymphoma
This Phase 2 trial tests whether pembrolizumab plus brentuximab works better than standard chemotherapy followed by an autologous stem cell transplant for people whose classic Hodgkin lymphoma has come back or did not respond. It may help by improving cancer control before and around stem cell transplant and by comparing outcomes between the two treatment approaches.
Concord, New South WalesAges 18 years+ - NCT05185505RecruitingPhase 4
Atezolizumab and bevacizumab before liver transplant for liver cancer
This trial tests giving atezolizumab plus bevacizumab before liver transplant in people with hepatocellular carcinoma (HCC) that is too advanced to be listed within the “Milan criteria,” but still transplant-eligible. The goal is to control the cancer outside the transplant period and improve transplant outcomes.
Houston, TexasAges 18 years+ - NCT05190653Recruiting
Support during stem cell or CAR T cancer treatment
This study tests whether starting palliative and supportive care early (alongside cancer treatment) can improve comfort and support for people having stem cell transplant or CAR T-cell therapy. It may also help family caregivers by offering support during a difficult treatment period.
Calgary, AlbertaAges 18 years+ - NCT05198570Recruiting
Measuring how acyclovir moves in children with cancer
This study checks how acyclovir behaves in the body when it’s given by mouth or through an IV to children receiving cancer care. It may help doctors better choose doses and monitor the medicine in kids who need prevention or treatment of certain viral infections.
Trieste, TSAges 6 months–18 years - NCT05215327RecruitingPhase 2
Higher-dose flu vaccine vs standard dose after lung transplant
This trial tests whether a higher dose of flu vaccine works better than the standard dose for people who have had a lung transplant. It may help improve protection against seasonal flu while monitoring safety.
Nashville, TennesseeAges 16 years+
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Common questions
- Are there clinical trials for transplant?
- Yes. Clin2 currently lists 1,497 recruiting transplant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.