Clinical trials
Treatment clinical trials
Below are recruiting treatment clinical trials, each written for real people, not researchers. We’re tracking 8,307 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05398861RecruitingPhase 2
Testing utidelone plus bevacizumab for HER2-negative advanced breast cancer
This trial studies whether utidelone combined with bevacizumab can shrink tumors and slow progression in women with advanced HER2-negative breast cancer that has already been treated at least twice. It may help people who have limited options after earlier chemotherapy and/or hormone (endocrine) treatments.
Zhengzhou, HenanAges 18–70 - NCT05362929Recruiting
Laser treatment for acne scars in darker skin tones
This study tests a new type of laser treatment for acne scars in people with darker skin tones. It aims to see if the laser is effective and safe for improving the appearance of scars.
Elmsford, New YorkAges 18 years+ - NCT05383911Recruiting
Sickle cell care plan choices for teens and young adults
This trial tests a way to help teens and young adults with sickle cell disease (SCD) and their caregivers actively take part in treatment decisions. It focuses on improving shared decision-making through interviews and a partner-centered approach.
Wilmington, DelawareAges 15 years+ - NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT05388682Recruiting
Treating Takayasu disease with lung artery involvement
This trial studies treatment for people with Takayasu arteritis when it affects the lung arteries. It may help reduce problems caused by narrowed or involved lung arteries.
Beijing, ChinaAges Any age - NCT05398679RecruitingPhase 4
Oral antibiotics versus IV antibiotics after heart infection
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
Alicante, AlicanteAges 18 years+ - NCT05404958Recruiting
Improve how HIV prevention and treatment services are integrated
This study looks at ways to better connect HIV prevention services with HIV treatment services in participating clinics. It mainly involves interviewing clinic leaders and staff, plus public health staff, to learn what’s working and how to improve care.
MombasaAges Any age - NCT05375370Recruiting
Testing a blood test to predict liver cancer coming back
This study checks whether a blood test (circulating tumor DNA) can help predict if hepatocellular carcinoma (HCC) will return after curative treatment like surgery or ablation. If it works, it may help doctors plan closer follow-up or earlier treatment if recurrence risk is higher.
RouenAges 18 years+ - NCT05384561Recruiting
Training your sense of smell to help after COVID
This trial studies whether structured smell (olfactory) training can improve ongoing smell problems after COVID-19. It may help people whose sense of smell hasn’t fully returned long after the infection.
Trois-Rivières, QuebecAges 18 years+ - NCT05386394RecruitingPhase 2
Brain stimulation to help primary progressive aphasia speech
This trial tests a non-painful brain stimulation method to improve language and speech problems caused by primary progressive aphasia. It may help some people communicate more clearly by targeting specific brain regions.
Baltimore, MarylandAges 50–90 - NCT05391490RecruitingPhase 1
Testing donated immune cells for advanced CD19 blood cancers
This early-phase trial tests donated (allogeneic) immune cells engineered to recognize CD19, a target found on many B-cell cancers. It’s designed for people whose CD19+ cancer has come back or didn’t respond after several previous treatments, aiming to shrink tumors and control disease.
LondonAges 16–65 - NCT05410457Recruiting
Study different treatments after ischemic stroke
This trial looks at which treatment approach after an ischemic stroke (a stroke caused by a blocked blood vessel) may lead to better outcomes. It may help doctors better choose treatments that improve recovery and prognosis.
Nanjing, JiangsuAges 18 years+ - NCT05364879Recruiting
Exercise before ovarian cancer surgery
This trial tests whether supervised exercise (before surgery) can help people with advanced ovarian cancer get ready for treatment. It’s meant to improve readiness and safety during the time leading up to surgery.
Halifax, Nova ScotiaAges 18 years+ - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT05384496RecruitingPhase 2
Axitinib and nivolumab for advanced mucosal melanoma
This trial studies how well two medicines—axitinib and nivolumab—work for people with advanced melanoma that starts in moist “mucosal” areas (like the mouth, nose, throat, or bowel). It may help shrink tumors and control the disease by boosting the immune system and targeting tumor growth.
Harrison, New YorkAges 18 years+ - NCT05371483Enrolling by invitation
Study effects of narcolepsy and hypersomnia treatments on brain and heart
This study looks at how narcolepsy or idiopathic hypersomnia affects thinking and cardiovascular health, and how usual treatment medications may change those outcomes. It may help researchers understand risks and benefits of common hypersomnia therapies.
Scottsdale, ArizonaAges 18–75 - NCT05404321Recruiting
Collecting tumor samples to study triple-negative breast cancer treatments
This study collects tumor tissue from people with early-stage triple-negative breast cancer before they start neoadjuvant chemotherapy. The goal is to help researchers test new therapies and look for markers that may predict who benefits.
CaenAges 18 years+ - NCT05401097RecruitingPhase 2
Venetoclax plus IDH-targeted pills for AML patients who can’t get intensive chemo
This Phase 2 trial tests different ways of using medicines that target IDH mutations (IDH-targeted treatment) plus venetoclax in people newly diagnosed with IDH-mutated AML. It’s designed for patients who cannot safely receive intensive induction chemotherapy, to see which approach works best and is tolerable.
Aurora, ColoradoAges 18 years+ - NCT05384145Recruiting
Improve HIV testing and follow-up in Alabama clinics
This trial is testing a “whole-people” plan to help more people get HIV tested, get connected to care, and stay on treatment. It is mainly for healthcare and community staff in specific Alabama counties.
Birmingham, AlabamaAges 13 years+ - NCT05408845RecruitingPhase 2
Study drug vs standard care for HER2 salivary gland cancer
This Phase 2 trial tests how well ado-trastuzumab emtansine (and compares to two standard treatment options) works for salivary gland cancers that are HER2-positive or HER2-low. It aims to see whether the study drug can control cancer better and with acceptable side effects.
Birmingham, AlabamaAges 18 years+ - NCT05319730RecruitingPhase 1/Phase 2
Testing new drugs, with or without pembrolizumab, for advanced esophageal cancer
This trial studies investigational cancer medicines, either alone or along with pembrolizumab, for people with advanced esophageal squamous cell cancer whose cancer has grown despite prior immune and platinum-based treatment. It may offer a new option after standard therapy has not worked.
Tucson, ArizonaAges 18 years+ - NCT05317858RecruitingPhase 3
Open the brain’s blood barrier to treat lung cancer brain spots
This trial tests whether using focused ultrasound to temporarily open the brain’s blood barrier—plus standard immune therapy—can better treat non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to help medicines reach the brain tumor spots more effectively, while still using the usual lung cancer treatment.
Phoenix, ArizonaAges 18–100 - NCT05334823RecruitingPhase 2
CAR T-cell treatment for CD19-positive relapsed leukemia in children
This Phase 2 trial tests pCAR-19B, a customized immune-cell treatment for children and teens with CD19-positive B-ALL that has come back or did not respond to standard therapy. If eligible, you would receive the cell infusion after cell collection and testing to make sure the leukemia cells have the right marker.
Beijing, Beijing MunicipalityAges 3–21 - NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75
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Common questions
- Are there clinical trials for treatment?
- Yes. Clin2 currently lists 8,307 recruiting treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.