Clinical trials
Type 2 Diabetes (T2DM) clinical trials
Below are recruiting type 2 diabetes (t2dm) clinical trials, each written for real people, not researchers. We’re tracking 230 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Anniston, AlabamaAges 18 years+ - NCT07156370Recruiting
Saliva cortisol test for hard-to-control diabetes
This study checks if a simple saliva test can find high cortisol levels in people with hard-to-control type 2 diabetes. It aims to help doctors identify if cortisol problems are making diabetes worse.
ShanghaiAges 18–80 - NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65 - NCT07719894RecruitingPhase 4
Preventing heart problems in type 2 diabetes with cilostazol and aspirin
This trial tests whether taking cilostazol and aspirin together can help prevent heart attacks, strokes, and other cardiovascular events in people with type 2 diabetes who have early signs of artery disease or metabolic syndrome. It aims to see if this combination is more effective than aspirin alone.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07270731RecruitingPhase 1
Study of a new medicine for type 2 diabetes and healthy volunteers
This study tests a new medicine (NNC9733-0001) to see how it works in healthy people and in people with type 2 diabetes. It helps researchers understand safety and how the body processes the drug.
NeussAges 18–64 - NCT02973412Recruiting
How sleep timing affects blood sugar in diabetes
This study looks at your daily sleep–wake timing (“chronotype”) and how it may affect blood sugar control in people with diabetes. It may help researchers learn whether sleep patterns could improve glucose levels.
LeicesterAges 18–75 - NCT03264352RecruitingPhase 4
Treatment for slightly high blood pressure in type 2 diabetes
This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.
Guangzhou, GuangdongAges 45–79 - NCT03987308Recruiting
Test shot medicine versus insulin pump for new type 2 diabetes
This study compares a continuous “under the skin” diabetes medicine (called beinaglutide) with an insulin pump (CSII) in people who were recently diagnosed with type 2 diabetes. It aims to see which approach works better and is safer for controlling blood sugar.
Beijing, Beijing MunicipalityAges 18–70 - NCT07703345Recruiting
Saliva markers in people with diabetes and gum disease
This study checks whether certain substances in saliva can help detect gum disease in people with type 2 diabetes. It compares the levels of these substances in people with diabetes and gum disease, people with gum disease only, people with diabetes only, and healthy volunteers.
Konya, KonyaAges 18–80 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Birmingham, AlabamaAges 18 years+ - NCT06884059RecruitingPhase 1
Time-restricted eating for people with early kidney signs
This study tests whether eating only during a certain window each day helps people with type 2 diabetes and small amounts of protein in their urine (a sign of early kidney stress) improve their health. You'll use a smartphone app to log your meals and follow a daily eating schedule.
La Jolla, CaliforniaAges 18–75 - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT04993482Recruiting
Tracks daily movement habits in adults with type 2 diabetes
This study looks at your usual 24-hour movement pattern (like being active, sitting, and sleeping). It may help researchers better understand daily behavior patterns in people with type 2 diabetes.
GhentAges 18–100 - NCT05026723Recruiting
Food plan to improve health for HIV and type 2 diabetes
This study tests whether a personalized “food as medicine” approach can help people manage health related to HIV and type 2 diabetes or prediabetes risk. If you struggle with having enough healthy food, the program may focus on practical ways to improve diet and support healthier blood sugar.
Chapel Hill, North CarolinaAges 18 years+ - NCT05124457RecruitingPhase 2
Detemir vs NPH insulin for diabetes in pregnancy
This Phase 2 study compares two types of insulin—insulin detemir vs NPH—to see which works better and is safe for controlling blood sugar during pregnancy. You may be invited if you are pregnant and need insulin for either pre-existing type 2 diabetes or gestational diabetes.
Los Angeles, CaliforniaAges 18 years+ - NCT05268237RecruitingPhase 1/Phase 2
Testing a diabetes pill under the tongue for type 2 diabetes
This early-phase study tests the safety and side effects of liraglutide taken under the tongue, and looks for early signs it improves blood sugar in people with type 2 diabetes. It may help people who want an alternative way to get this medication, but the main goal is to see how safe and tolerable it is.
Hong KongAges 18–65 - NCT05354947Recruiting
Ultrasound test in adults with type 2 diabetes
This study tests whether a series of ultrasound treatments can improve blood sugar control in people with type 2 diabetes. You may be asked to stay on your current diabetes pills and avoid certain other medicines during the study.
New Haven, ConnecticutAges 21–75 - NCT05363761RecruitingPhase 1
Artery procedure to treat type 2 diabetes and related problems
This Phase 1 study tests a new artery “ablation” procedure for people with type 2 diabetes, aiming to improve diabetes and related conditions like high blood pressure. It will also check whether the procedure is safe and works well enough to study further.
Panama CityAges 21–65 - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT05469659RecruitingPhase 2
Test drug to slow kidney damage in type 2 diabetes
This Phase 2 study compares tofogliflozin to metformin to see how well they reduce urine albumin levels (a marker of kidney stress) in people with diabetic kidney disease. You might benefit if your type 2 diabetes is affecting your kidneys despite standard blood-pressure medicines.
Matsumoto, NaganoAges 20 years+ - NCT05580536Recruiting
Text-message program for Arab Americans with type 2 diabetes
This study tests a diabetes support program designed for Arab Americans, using regular text messages and materials in Arabic and English. It may help people improve blood sugar control and stay engaged in their care.
El Cajon, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for type 2 diabetes (t2dm)?
- Yes. Clin2 currently lists 230 recruiting type 2 diabetes (t2dm) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes (t2dm) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes (t2dm) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.