Clinical trials · California
Type 2 diabetes clinical trials in California
We’re tracking 112 recruiting type 2 diabetes studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05124457RecruitingPhase 2
Detemir vs NPH insulin for diabetes in pregnancy
This Phase 2 study compares two types of insulin—insulin detemir vs NPH—to see which works better and is safe for controlling blood sugar during pregnancy. You may be invited if you are pregnant and need insulin for either pre-existing type 2 diabetes or gestational diabetes.
Los Angeles, CaliforniaAges 18 years+ - NCT07864168Recruiting
Long-lasting glucose sensor study for type 1 and type 2 diabetes
This study tests a new extended-wear sensor that helps track glucose levels continuously. It is designed to see if a next-generation sensor is accurate and safe for people with diabetes.
Chula Vista, CaliforniaAges 2–80 - NCT06746714Recruiting
Preventing low blood sugar in high-risk type 2 diabetes
This study tests a program to help people with type 2 diabetes who are at high risk for low blood sugar (hypoglycemia) avoid dangerous drops. It may help you better manage your blood sugar and reduce worrying episodes.
Pleasanton, CaliforniaAges 18 years+ - NCT07868250Recruiting
Meal planning help for type 2 diabetes
This study tests if a program of medical nutrition therapy can help people with type 2 diabetes manage their blood sugar. You would work with a dietitian to create a meal plan that fits your life.
Fontana, CaliforniaAges 18–75 - NCT07843485RecruitingPhase 3
Weight loss medication for adults with type 2 diabetes
This study tests a new medicine called petrelintide to help people with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be an option if you've struggled with weight loss through diet alone.
Los Angeles, CaliforniaAges 18 years+ - NCT07817251RecruitingPhase 3
Switching From Semaglutide to Cagrisema in Type 2 Diabetes
This study looks at how people with type 2 diabetes tolerate switching from a weekly semaglutide injection (like Ozempic or Wegovy) to a new experimental medicine called Cagrisema. The goal is to see if the switch is safe and effective.
Fountain Valley, CaliforniaAges 18 years+ - NCT07797335RecruitingPhase 3
Zenagamtide for diabetes and weight loss
This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.
Lancaster, CaliforniaAges 45 years+ - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Bakersfield, CaliforniaAges 18 years+ - NCT07776509RecruitingPhase 3
Adding a new drug to current weight-loss therapy for adults with obesity or overweight
This study tests a new medication (AZD6234) added to your current weight-management medication (an incretin-based drug) to see if it helps with weight loss. You may be eligible if you are overweight or obese with related health issues or type 2 diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07754461RecruitingPhase 3
Survodutide for blood sugar control in type 2 diabetes
This study tests an investigational drug called survodutide to see if it helps people with type 2 diabetes manage their blood sugar levels. Participants will receive either survodutide or a placebo, and the study will compare changes in HbA1c (a measure of blood sugar control).
Canoga Park, CaliforniaAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Banning, CaliforniaAges 18 years+ - NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Fountain Valley, CaliforniaAges 18–75 - NCT07664553RecruitingPhase 3
Testing a new diabetes tablet for people on insulin
This trial tests a new once-daily tablet (elecoglipron) against a placebo to see if it can help improve blood sugar control in adults with type 2 diabetes who are already on insulin. It may offer an additional treatment option to help manage your diabetes.
Sacramento, CaliforniaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sacramento, CaliforniaAges 18 years+ - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Sacramento, CaliforniaAges 18 years+ - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Bakersfield, CaliforniaAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
San Diego, CaliforniaAges 18 years+ - NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Lincoln, CaliforniaAges 18 years+ - NCT07598773Enrolling by invitation
Continuous glucose monitoring study for prediabetes and type 2 diabetes
This study asks you to wear a glucose monitor and smart ring for several months to help researchers understand how blood sugar changes throughout the day in people with prediabetes or type 2 diabetes. The goal is to learn how lifestyle and medications affect blood sugar control.
San Francisco, CaliforniaAges 18 years+ - NCT07590193RecruitingPhase 1
AMG 127 Safety Study in Healthy People and Type 2 Diabetes
This early-stage trial tests a new drug called AMG 127 to see if it's safe and how the body handles it. Researchers will enroll both healthy volunteers and people with type 2 diabetes to understand how the drug works in different groups.
Lake Forest, CaliforniaAges 18–75 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Santa Barbara, CaliforniaAges 14–75 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Northridge, CaliforniaAges 18 years+ - NCT07546929RecruitingPhase 2
HP-211 Safety Study for Type 2 Diabetes Treatment
This study tests a new medicine called HP-211 in people with early-stage type 2 diabetes to see if it's safe and helps control blood sugar. You'd take the study drug along with your current diabetes management.
Canoga Park, CaliforniaAges 18 years+ - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Walnut Creek, CaliforniaAges 18 years+
Type 2 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 2 diabetes studies listed above.
- Research Site · 8 studies
- Ark Clinical Research · 3 studies
- Diablo Clinical Research · 3 studies
- Valley Clinical Trials, Inc. · 3 studies
- Clinical Trials Research_Sacramento · 2 studies
- Headlands Research California, LLC · 2 studies
- Linda Vista Health Care Ctr · 2 studies
- Pacific Clinical Studies · 2 studies
What taking part in a type 2 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 2 diabetes trials in other states
Common questions
- Are there type 2 diabetes clinical trials in California?
- Yes. We're currently tracking 112 recruiting type 2 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 2 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 2 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.