Clinical trials · California
Type 2 diabetes clinical trials in California
We’re tracking 105 recruiting type 2 diabetes studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07754461RecruitingPhase 3
Survodutide for blood sugar control in type 2 diabetes
This study tests an investigational drug called survodutide to see if it helps people with type 2 diabetes manage their blood sugar levels. Participants will receive either survodutide or a placebo, and the study will compare changes in HbA1c (a measure of blood sugar control).
Canoga Park, CaliforniaAges 18 years+ - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Newport Beach, CaliforniaAges 12–35 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Beverly Hills, CaliforniaAges 18 years+ - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Cerritos, CaliforniaAges 18–75 - NCT06057662Enrolling by invitation
Personalized diabetes support for newly diagnosed children
This study offers personalized support to help families manage type 1 diabetes in a newly diagnosed child. It includes education, monitoring, and guidance from a diabetes team for 2 years.
Sacramento, CaliforniaAges birth–16 years - NCT05752292Enrolling by invitation
Pregnant with gestational diabetes: share risk info to help
This study is testing how to share risk information during pregnancy in a way that helps patients feel more informed and empowered. It includes people currently pregnant with gestational diabetes and will ask about your preferences and understanding.
Pleasanton, CaliforniaAges 18 years+ - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Banning, CaliforniaAges 18 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Lake Forest, CaliforniaAges 18 years+ - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Escondido, CaliforniaAges 7–85 - NCT06329375Recruiting
Food Help for Diabetes Patients After Hospital Stay
This study helps people with diabetes who are admitted to Stanford Hospital and have trouble affording enough food. It provides meals through Mom's Meals after you go home, to make sure you have healthy food options.
Palo Alto, CaliforniaAges 18 years+ - NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Fountain Valley, CaliforniaAges 18–75 - NCT07502495RecruitingPhase 2
Icovamenib for type 2 diabetes not reaching glucose goals
This study tests an investigational pill called icovamenib for people with type 2 diabetes who have not reached their blood sugar targets with current medications. It aims to see if the drug can help improve blood sugar control.
Canoga Park, CaliforniaAges 18–75 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Los Angeles, CaliforniaAges 40–80 - NCT06296485Recruiting
Safer Aging with Diabetes Monitoring
This study tests a way to help older adults with type 2 diabetes who use insulin avoid dangerously low blood sugar. You would use a continuous glucose monitor and get support via email or internet to stay safe.
Fremont, CaliforniaAges 75 years+ - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Bakersfield, CaliforniaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Concord, CaliforniaAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
Lomita, CaliforniaAges 18 years+ - NCT07664553RecruitingPhase 3
Testing a new diabetes tablet for people on insulin
This trial tests a new once-daily tablet (elecoglipron) against a placebo to see if it can help improve blood sugar control in adults with type 2 diabetes who are already on insulin. It may offer an additional treatment option to help manage your diabetes.
Sacramento, CaliforniaAges 18 years+ - NCT07590193RecruitingPhase 1
AMG 127 Safety Study in Healthy People and Type 2 Diabetes
This early-stage trial tests a new drug called AMG 127 to see if it's safe and how the body handles it. Researchers will enroll both healthy volunteers and people with type 2 diabetes to understand how the drug works in different groups.
Lake Forest, CaliforniaAges 18–75 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Los Angeles, CaliforniaAges 18–75 - NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+ - NCT07724340RecruitingPhase 2
Study of AT673 plus semaglutide for type 2 diabetes and weight loss
This study tests a new medication called AT673 combined with semaglutide (Wegovy) to help people with type 2 diabetes and overweight or obesity lose weight and improve blood sugar. It is for people who have tried diet and exercise to lose weight but haven't had success.
Anaheim, CaliforniaAges 18 years+ - NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65
Type 2 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 2 diabetes studies listed above.
- Ark Clinical Research · 6 studies
- Research Site · 4 studies
- Catalina Research Institute · 3 studies
- Diablo Clinical Research · 3 studies
- Sansum Diabetes Research Institute · 3 studies
- Encompass Clinical Research · 2 studies
- Hoag Memorial Hospital Presbyterian · 2 studies
- Hope Clinical Research · 2 studies
What taking part in a type 2 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 2 diabetes trials in other states
Common questions
- Are there type 2 diabetes clinical trials in California?
- Yes. We're currently tracking 105 recruiting type 2 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 2 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 2 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.