Clinical trials · California
Type 2 diabetes clinical trials in California
We’re tracking 106 recruiting type 2 diabetes studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Covina, CaliforniaAges 18 years+ - NCT04783441Recruiting
Continuous glucose sensor study after kidney transplant
This study checks whether using a continuous glucose monitor (a sensor that tracks sugar throughout the day) is helpful and practical for people with a recent kidney transplant and type 2 diabetes on insulin. You may need to wear the sensor continuously and still do finger-stick glucose checks for safety.
Sacramento, CaliforniaAges 18 years+ - NCT05124457RecruitingPhase 2
Detemir vs NPH insulin for diabetes in pregnancy
This Phase 2 study compares two types of insulin—insulin detemir vs NPH—to see which works better and is safe for controlling blood sugar during pregnancy. You may be invited if you are pregnant and need insulin for either pre-existing type 2 diabetes or gestational diabetes.
Los Angeles, CaliforniaAges 18 years+ - NCT05138432Recruiting
More fresh fruit and vegetables for kids with type 2 diabetes
This study tests whether giving families extra fresh fruits and vegetables helps children manage type 2 diabetes. It’s delivered through a “prescription” program and may support healthier eating habits.
San Diego, CaliforniaAges Up to 18 years - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05322213RecruitingPhase 1
THC study for blood sugar control in type 2 diabetes
This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.
La Jolla, CaliforniaAges 21–70 - NCT05570734Recruiting
Study of diabetes support for Hispanic/Latino adults online
This study looks at an online (e-health) way to help adults with type 2 diabetes better follow their diabetes care plan. It targets Hispanic/Latino patients and may help improve how consistently people manage their diabetes.
Chula Vista, CaliforniaAges 18 years+ - NCT05580536Recruiting
Text-message program for Arab Americans with type 2 diabetes
This study tests a diabetes support program designed for Arab Americans, using regular text messages and materials in Arabic and English. It may help people improve blood sugar control and stay engaged in their care.
El Cajon, CaliforniaAges 18 years+ - NCT06251323Recruiting
Better diabetes care with team support and technology
This study tests a new way to help adults with type 2 diabetes get better care. It includes a team of healthcare providers and uses technology to support your treatment.
Stanford, CaliforniaAges 18 years+ - NCT06398093Recruiting
Self-compassion tool kit for type 2 diabetes distress
This study tests a self-compassion tool kit designed to help people with type 2 diabetes feel less stressed and more in control of their condition. If you have type 2 diabetes and are feeling some distress about it, this program may offer practical support to improve your daily life.
San Diego, CaliforniaAges 18 years+ - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Los Angeles, CaliforniaAges Any age - NCT06516640Recruiting
CGM Education for Type 2 Diabetes
This trial helps teens and young adults with type 2 diabetes learn to use continuous glucose monitors (CGMs). It aims to make managing diabetes easier and more effective.
Los Angeles, CaliforniaAges 8–21 - NCT06525259Recruiting
Study on risk factors for type 2 diabetes in youth
This study looks for children and teens who are at high risk of developing type 2 diabetes to understand what factors lead to it. If your child is overweight, has slightly high blood sugar, and is in early to mid-puberty, they may be able to join.
Los Angeles, CaliforniaAges 8–15 - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
San Diego, CaliforniaAges 18–50 - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Stanford, CaliforniaAges 30–70 - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Los Angeles, CaliforniaAges 10–17 - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Santa Ana, CaliforniaAges 18–75 - NCT06923046Recruiting
Team Clinic for teens with type 2 diabetes
This trial tests a group clinic program for teens with type 2 diabetes. It aims to help you manage your diabetes better with support from others your age and your family.
Los Angeles, CaliforniaAges 12–18 - NCT07065721Recruiting
Continuous glucose monitors for young adults with type 2 diabetes
This trial tests if using a continuous glucose monitor (a small sensor that checks your sugar levels without fingersticks) helps young adults manage type 2 diabetes better. You will wear the sensor and use a phone app to track your glucose.
San Diego, CaliforniaAges 18–45 - NCT07176793Recruiting
Breastfeeding support after gestational diabetes
This study tests a breastfeeding support program for people who had gestational diabetes during pregnancy. The goal is to see if this support helps them breastfeed longer and stay healthy.
Sacramento, CaliforniaAges 18 years+ - NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
La Jolla, CaliforniaAges 18 years+ - NCT07225218Recruiting
Diabetes prevention program for UCLA students
This study tests a wellness program for UCLA undergraduates who are at risk for developing diabetes. It aims to help students prevent diabetes through support and education.
Los Angeles, CaliforniaAges 17–25 - NCT07260110Recruiting
Study of teplizumab vs. no treatment in stage 2 type 1 diabetes
This study watches people with stage 2 type 1 diabetes who either get teplizumab or not, to compare their real-world experiences. It helps researchers learn how the drug affects daily life.
San Francisco, CaliforniaAges 8 years+
Type 2 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 2 diabetes studies listed above.
- University of California, Los Angeles (UCLA) · 4 studies
- Children's Hospital Los Angeles · 3 studies
- University of California, San Francisco · 3 studies
- Scripps Health · 2 studies
- University of California San Diego · 2 studies
- University of California, Davis Medical Center · 2 studies
- Altman Clinical and Translational Research Institute
- Clinical Trial Site
What taking part in a type 2 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 2 diabetes trials in other states
Common questions
- Are there type 2 diabetes clinical trials in California?
- Yes. We're currently tracking 106 recruiting type 2 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 2 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 2 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.