Clinical trials
Urothelial Bladder Cancer clinical trials
Below are recruiting urothelial bladder cancer clinical trials, each written for real people, not researchers. We’re tracking 213 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07073703Recruiting
A personalized program for frailty in bladder or kidney cancer patients
This trial tests a personalized 6-month program to reduce frailty in older patients who are about to have surgery for bladder or kidney cancer. The program includes exercise and support, and aims to help patients stay stronger during and after treatment.
Saint-EtienneAges 65 years+ - NCT07080333Recruiting
Bladder cancer and the gut microbiome study
This study looks at the bacteria in your gut and bladder to understand how they may relate to bladder cancer. It is for men who are having their first tumor removal for suspected bladder cancer, and helps researchers learn if the microbiome plays a role.
CannesAges 18 years+ - NCT07087860RecruitingPhase 2
Plasma exchange plus targeted therapy for advanced bladder cancer
This trial tests a procedure called therapeutic plasma exchange (TPE) combined with the drugs enfortumab vedotin and pembrolizumab for people with advanced bladder cancer that has stopped responding to standard treatments. The goal is to see if TPE helps the drugs work better.
Rochester, MinnesotaAges 18 years+ - NCT07097142RecruitingPhase 3
Shorter radiation for bladder cancer with chemo
This trial tests if a shorter course of radiation therapy works as well as the usual longer course for people with bladder cancer who are also receiving standard chemotherapy. The goal is to see if shorter treatment can reduce side effects while still being effective.
Fort Smith, ArkansasAges 18 years+ - NCT07129993RecruitingPhase 2/Phase 3
Comparing two drug combinations for advanced bladder cancer
This trial tests a new drug combination (Dato-DXd plus chemotherapy) against a standard chemotherapy combination for advanced bladder cancer that has spread or cannot be removed by surgery. It is for people whose cancer has grown after treatment with the drugs enfortumab vedotin (Padcev) and pembrolizumab (Keytruda).
Fullerton, CaliforniaAges 18 years+ - NCT07130578Recruiting
Urine DNA test to guide second bladder cancer surgery
This trial is testing whether a urine test for tumor DNA/RNA can help guide the decision for a second surgery in people with high-risk, non-muscle-invasive bladder cancer. It aims to see if the urine test can predict who needs the second surgery, potentially avoiding unnecessary procedures.
TianjinAges 18 years+ - NCT07180212Recruiting
Urine DNA Test to Guide Cystoscopy in High-Risk Bladder Cancer
This trial tests a urine test that looks for tumor DNA to help doctors decide when you need a cystoscopy (a scope in the bladder). It is for people with high-risk or very high-risk non-muscle-invasive bladder cancer who have already had surgery to remove all visible tumors.
Xingtai, HebeiAges 18 years+ - NCT07187635Recruiting
Urine DNA test before a second bladder tumor surgery
This trial studies if a urine test for tumor DNA can help decide when a second surgery is needed for early stage bladder cancer. It may reduce unnecessary procedures for some patients.
Nanchang, AnhuiAges 18 years+ - NCT07225127Recruiting
Bladder cancer treatment: therapy vs. surgery
This study compares two standard treatments for high-grade non-muscle-invasive bladder cancer that has come back after initial treatment: medication placed directly into the bladder (intravesical therapy) or bladder removal surgery (cystectomy). The goal is to see which option works better for patients like you.
Tampa, FloridaAges 18 years+ - NCT07225205Recruiting
Home IV fluids after bladder removal surgery
This trial tests if giving IV fluids at home after bladder removal surgery is safe and helpful. It aims to reduce dehydration and hospital visits after you go home.
Baltimore, MarylandAges 18 years+ - NCT07234968Recruiting
Stent vs no stent after bladder removal surgery
This study looks at whether leaving a small tube (ureteral stent) in place after bladder removal helps recovery. It compares people who get a stent to those who don't, focusing on problems like leaks or infections after surgery.
Philadelphia, PennsylvaniaAges 18–85 - NCT07000084RecruitingPhase 3
Testing gemcitabine with BCG for returning bladder cancer
This trial tests whether adding a chemotherapy drug called gemcitabine to the usual BCG therapy can help prevent bladder cancer from coming back again. If you have had BCG before and your cancer returned, this study might offer a more effective treatment option.
Birmingham, AlabamaAges 18 years+ - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+ - NCT07322263RecruitingPhase 2
Gemcitabine and docetaxel for bladder cancer that returned after BCG
This trial tests a combination of two chemotherapy drugs (gemcitabine and docetaxel) given directly into the bladder to treat high-risk non-muscle-invasive bladder cancer that has come back or not responded to BCG therapy. It's for people who cannot or choose not to have their bladder removed.
Iowa City, IowaAges 18–99 - NCT07395037Recruiting
Study of emergency hospital stays for blood in urine
This study is looking at why people are admitted to the hospital as an emergency because of blood in their urine (hematuria). If you are being cared for by the urology team and stay for at least a day, you might be able to join.
LondonAges 18 years+ - NCT00872495Recruiting
Tests urine and bladder checks for bladder cancer
This trial tests non-invasive tests (using urine samples and scheduled bladder procedures) to help detect bladder cancer. It may be helpful if you are having bladder evaluation or surgery and your care team wants better ways to detect cancer without invasive testing beyond what you already need.
Burlington, MassachusettsAges 18 years+ - NCT01050504Recruiting
Donate blood and tissue to study recurrent or metastatic cancers
This study collects and studies blood and, when possible, small tissue samples from people with prostate or bladder/urothelial cancer that has come back or spread. The goal is to better understand these cancers and support future research that may lead to better care.
Seattle, WashingtonAges 18 years+ - NCT02379429Recruiting
Collecting bladder/urothelial cancer tissue for future research
This study looks at urothelial cancer (often bladder cancer) samples taken during diagnosis or standard treatment. It may help researchers better understand the disease by using tissue that doctors already need to collect for care.
Bethesda, MarylandAges 18–120 - NCT07119996RecruitingPhase 1
Vitamin B3 to boost immunotherapy for bladder cancer
This trial tests whether taking vitamin B3 can help immunotherapy work better for people with bladder cancer. It’s for patients who have a certain type of bladder cancer and have had a recent infection that needed antibiotics.
Guangzhou, GuangdongAges 18 years+ - NCT07413523Recruiting
Radiation therapy plus standard care for urothelial cancer with limited spread
This trial tests whether adding targeted radiation therapy to standard drug treatment can help people with urothelial cancer that has spread to a few spots (up to 3 outside the brain). If you are starting your first or second round of systemic therapy, this study may be an option.
Rozzano, MilanAges 18 years+ - NCT07420517RecruitingPhase 2
Dutasteride for low-grade bladder cancer
This trial tests if the drug dutasteride can help people with a slow-growing type of bladder cancer that hasn't spread into the muscle wall. It may be an option for those not receiving other standard treatments like BCG therapy or chemotherapy directly into the bladder.
Québec, QuebecAges 18 years+ - NCT07424560Recruiting
Bladder Cancer DNA Testing Study
This study looks for specific DNA changes in bladder cancer tumors using a precise test. It aims to better understand the disease and may help guide future treatment choices.
Lanzhou, GansuAges 18 years+ - NCT07441499Recruiting
Detecting bladder cancer recurrence with a blood test
This study uses a blood test to find and monitor urothelial cancer (a type of bladder cancer) and to watch for signs it may come back. It may help patients and doctors make better decisions about follow-up care.
TianjinAges 18 years+ - NCT07475403RecruitingPhase 2
Immunotherapy guided by urine DNA for high risk bladder cancer
This trial tests a new immunotherapy approach for people with a very high risk type of bladder cancer that hasn't spread into the muscle layer. The treatment is guided by a special urine test that looks for tumor DNA, and it may help if surgery cannot remove all the cancer or you choose not to have your bladder removed.
TianjinAges 18 years+
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Common questions
- Are there clinical trials for urothelial bladder cancer?
- Yes. Clin2 currently lists 213 recruiting urothelial bladder cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a urothelial bladder cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a urothelial bladder cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.