Clinical trials
Vaccination clinical trials
Below are recruiting vaccination clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03501576Recruiting
Testing a flu or COVID vaccine response in people with lymphoma
This study checks how your immune system responds after getting a vaccine. It focuses on people with different types of lymphoma, aiming to learn which immune responses can be measured and whether the vaccines are safe for you.
Atlanta, GeorgiaAges 18 years+ - NCT03354728RecruitingPhase 1/Phase 2
Vaccine trial for children with CMV after stem cell transplant
This trial studies a vaccine designed to help the body fight cytomegalovirus (CMV) in children who test positive for CMV and are about to receive a donor stem cell transplant. If it works, it may reduce CMV-related illness during recovery after transplant.
Duarte, CaliforniaAges 1–21 - NCT02471378Recruiting
Testing a malaria vaccine in pregnant people with malaria
This study looks at lab tests for malaria vaccine candidates in pregnant women who currently have malaria. It may help researchers understand which vaccine approaches are safest and most promising for pregnancy.
BamakoAges 15–25 - NCT02455479RecruitingPhase 1
Safety study of a vaccine for cocaine dependence
This early-stage study tests how safe an experimental “cocaine vaccine” is and how the body reacts to it. You must also be in behavioral therapy, and the study aims to see whether the vaccine can be given safely to people with cocaine use disorder.
New York, New YorkAges 21–69 - NCT01374984Enrolling by invitation
Test VIGIV treatment for serious complications from smallpox vaccination
This trial looks at how well a medicine called VIGIV works for people who develop serious or unusual vaccinia (smallpox-type) infections or complications after smallpox vaccination. It is mainly for specific skin and body-area problems, including eczema-related complications.
Ages Any age - NCT01244802Enrolling by invitation
Study of immune memory after yellow fever vaccination
This study looks at how your immune system “remembers” the yellow fever vaccine over time. It may help researchers understand long-term immune protection and how it varies between people.
Decatur, GeorgiaAges 18 years+ - NCT04910802RecruitingPhase 4
HPV vaccine with routine HPV screening for ages 22–26
This study looks at giving the HPV vaccine (Gardasil 9) to women while they go through Sweden’s routine HPV screening. It helps researchers understand how vaccine use alongside screening affects HPV infection and cervical cancer prevention.
StockholmAges 22–27 - NCT05554068RecruitingPhase 2
Testing the shingles vaccine response after bone marrow transplant
This Phase 2 study looks at how well the shingles vaccine works in people who had an allogeneic (donor) stem cell transplant. It aims to measure the body’s immune response to the vaccine and check that it’s safe in this recovery period.
Maywood, IllinoisAges Any age - NCT05631886RecruitingPhase 1
Testing a cancer vaccine plus immune therapy for hard tumors
This early-phase trial tests whether combining a lab-made CAR-DC cancer vaccine with immune checkpoint medicines can shrink tumors that have specific genetic changes. It’s meant for people with advanced or returning (relapsed) solid tumors or certain lymphomas that match required tumor markers.
Beijing, Beijing MunicipalityAges 18–75 - NCT06026774RecruitingPhase 1
Personalized mRNA Vaccine After Digestive Cancer Surgery
This trial tests a personalized mRNA vaccine designed to train your immune system to fight your specific cancer. It's for people who have just had surgery to remove a digestive system cancer (like pancreatic or colorectal) and will also receive standard chemotherapy after surgery.
Hangzhou, ZhejiangAges 18–75 - NCT06019702RecruitingPhase 1
Personalized mRNA vaccine for advanced digestive cancers
This trial tests a personalized mRNA vaccine designed to target unique markers on your cancer cells. The vaccine is made just for you based on genetic testing of your tumor. It is for people with advanced digestive system cancers who have run out of standard options.
Hangzhou, ZhejiangAges 18–75 - NCT06026800RecruitingPhase 1
Personalized mRNA vaccine plus standard treatment for advanced digestive cancers
This trial tests a personalized mRNA vaccine (iNeo-Vac-R01) given alongside standard first-line treatment for advanced digestive system cancers. The vaccine is made specifically for your tumor's unique genetic changes (neoantigens) and aims to help your immune system fight the cancer more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT05344209RecruitingPhase 2
Pembrolizumab plus or minus vaccine for advanced lung cancer
This Phase 2 trial studies pembrolizumab (an immune-boosting cancer medicine) alone or with an added investigational UV1 vaccine in people with advanced non-small cell lung cancer. It aims to see whether adding the vaccine improves safety and effectiveness, especially in tumors with high PD-L1 levels.
Drammen, AkershusAges 18 years+ - NCT05616546RecruitingPhase 4
Study of immune responses during and after flu infection
This study looks at how your immune system (your body’s infection-fighting system) responds during and around the time of a flu illness. It’s meant to help researchers better understand immune changes in healthy adults and may guide future flu care.
Atlanta, GeorgiaAges 18–64 - NCT06305910RecruitingPhase 1
Vaccine immunotherapy for recurrent brain tumors or newly diagnosed DIPG
This trial tests a combination of a vaccine made from tumor cells and a drug that may boost the immune system's ability to fight brain tumors. It is for children and young adults with a recurrent high-grade glioma or a newly diagnosed diffuse midline glioma with a specific genetic marker (H3K27M).
Minneapolis, MinnesotaAges 2–25 - NCT06326736RecruitingEarly Phase 1
mRNA vaccine after surgery for pancreatic cancer
This trial tests a personalized mRNA vaccine (made from your tumor's unique markers) combined with standard chemotherapy after surgery for pancreatic cancer. The goal is to see if the vaccine can help prevent the cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT06441110RecruitingPhase 3
BCG instillation for medium- to high-risk bladder cancer
This trial tests whether a specific schedule of BCG (a weakened germ that boosts the immune system) placed directly into the bladder is safe and effective for medium- to high-risk bladder cancer that hasn't grown into the muscle. It aims to see if adjusting the standard BCG course can work better for people with a PD-L1-positive tumor.
Fuzhou, FujianAges 18–75 - NCT07842367RecruitingPhase 2
How inflammation affects doctors' decisions
This study looks at how inflammation in the body may affect doctors' thinking and treatment choices. As part of the study, you would receive a flu vaccine, and researchers will measure your body's response and how it might influence your medical decisions.
Fayetteville, ArkansasAges 18 years+ - NCT07817108RecruitingPhase 3
Shingles mRNA vaccine trial for adults 40 and older
This study tests a new shingles vaccine (called an mRNA vaccine) given as a shot. It aims to prevent shingles in adults aged 40 and above. If you qualify, you may receive the vaccine or a placebo, and your health will be monitored for a period of time.
JinanAges 40 years+ - NCT06492187Recruiting
Survey to see if you qualify for infectious disease studies
This trial is a quick survey to see if you might be eligible for future infectious disease studies. It helps researchers understand your health background and find the right study for you.
Brooklyn, New YorkAges 18 years+ - NCT07786467Recruiting
Improving flu vaccine response with hands-on therapy in at-risk adults
This study tests whether a hands-on therapy called osteopathic manipulative treatment (OMT) can improve the body's response to the flu vaccine. If you are an adult who is willing to get both the flu shot and OMT, this could help make the vaccine more effective for you.
Erie, PennsylvaniaAges 18 years+ - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07783243Recruiting
Leishmaniasis vaccine response study in Ethiopia
This study tests how your immune system responds to parts of a potential vaccine for leishmaniasis. Doctors will take small blood or skin samples to see if your body's cells react to these vaccine pieces, which could help design a better vaccine in the future.
Addis AbabaAges 18–65 - NCT05923333Recruiting
Breastfed infants of HIV-exposed mothers get a probiotic
This study gives a specific probiotic (from B. infantis) to babies born without HIV to see if it can improve the baby’s early immune health. It focuses on babies who are HIV-exposed because their mother has HIV and plans to exclusively breastfeed for the first 6 months.
Cape TownAges birth–50 years
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Common questions
- Are there clinical trials for vaccination?
- Yes. Clin2 currently lists 575 recruiting vaccination studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccination trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccination trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.