Clinical trials
Valvular Heart Disease clinical trials
Below are recruiting valvular heart disease clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06590467Recruiting
Abbott heart device registry study
This registry is a large, ongoing study that collects information about Abbott heart devices used in routine care. It helps doctors learn how well these devices work and how patients are doing over time, without changing your treatment plan.
Los Angeles, CaliforniaAges Any age - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT06077201Recruiting
Home-based heart rehab after valve procedure
This study tests a home-based exercise program using a mobile app and activity tracker for people who have had a heart valve procedure. It aims to help you safely recover and improve your fitness at home.
Nashville, TennesseeAges 18 years+ - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT05935605Recruiting
Study pulmonary hypertension in heart failure and valve disease
This study looks at pulmonary hypertension—high blood pressure in the lung arteries—in people with certain heart conditions (heart failure with preserved or reduced pumping function, or significant valve disease). It may help doctors better understand how lung blood pressure changes in these heart problems and guide care.
Rochester, MinnesotaAges 18 years+ - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT05654272Recruiting
Testing CIRC imaging technology for people with heart problems
This study is developing and testing CIRC technologies using heart imaging. You may be able to join if you’re an adult with cardiovascular (heart) disease and can safely have the MRI scans.
Cleveland, OhioAges 18 years+ - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05208567Recruiting
Testing heart ultrasound in older adults with weak heart pumping
This trial uses a heart ultrasound test to find people who may have weak heart pumping function, especially in a multi-ethnic community. It may help improve how doctors detect this condition earlier using ultrasound images.
LondonAges 65 years+ - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04843371Recruiting
Using wearable data to predict heart pump strength
This trial tests whether a wearable device (Biostrap) can help predict how strongly your heart pumps, using echocardiogram (heart ultrasound) results. It may help doctors better estimate heart function from simpler measurements.
New Orleans, LouisianaAges 18–120 - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT03488732Recruiting
Heart valve disease registry for people needing valve treatment
This study is a registry that collects information about people with severe heart valve problems who are planning to have a valve procedure. It may help doctors better understand your condition and treatment over time.
MünchenAges 18 years+ - NCT07373119Enrolling by invitation
Frailty reduction in stable heart disease patients
This study tests a program to reduce frailty in older adults with stable coronary artery disease. The goal is to improve strength and well-being in people who are not having recent heart problems.
Barcelona, Select...Ages 70 years+ - NCT07094737Recruiting
Cardiac rehabilitation for heart attack and heart failure recovery
This study tracks patients with heart disease or heart failure who are in cardiac rehabilitation. The goal is to understand how well these programs work in real life and improve care for future patients.
MilanAges 18 years+ - NCT07572032RecruitingPhase 4
Delayed heart failure medications after fixing the cause
This study tests whether starting two heart failure medications later, after a procedure to fix the heart's problem, is safe and helpful. It aims to see if waiting a bit can still improve heart function and quality of life.
Daegu, DaeguAges 18 years+ - NCT07197736Recruiting
Improving heart ultrasound use at Columbia
This study involves cardiologists who read heart ultrasounds in Columbia's echo lab. It aims to improve how these tests are used to help patients.
New York, New YorkAges 18 years+ - NCT07192211RecruitingPhase 2
Study of ADR-002K for Heart Failure Patients Having Bypass Surgery
This study tests an experimental drug (ADR-002K) for people with heart failure caused by blocked arteries who are about to have bypass surgery. The goal is to see if it helps the heart recover better after surgery.
Osaka, SuitaAges 18–80 - NCT07057466Recruiting
AI heart check for hidden valve, pressure, or pump problems
This study uses an artificial intelligence (AI) program to read your ECG (a heart tracing) and detect early signs of heart failure, high blood pressure in the lungs, or valve disease before you have symptoms. The goal is to see if AI can catch these problems early.
BristolAges 18–90 - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+ - NCT07023510Recruiting
VALVE-AI: A study of heart valve health
This trial is testing a new way to check for heart valve problems using your recent ECG (heart electrical test). If you're 60 to 85 and haven't had recent heart imaging or known valve disease, you may qualify.
TaipeiAges 60–85
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Common questions
- Are there clinical trials for valvular heart disease?
- Yes. Clin2 currently lists 118 recruiting valvular heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.