Clinical trials
Valvular Heart Disease clinical trials
Below are recruiting valvular heart disease clinical trials, each written for real people, not researchers. We’re tracking 117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07065500Recruiting
Study of new metabolites for heart valve disease
This study looks at certain byproducts in your body (metabolites) that may be linked to heart valve disease. The goal is to understand how they work, which could lead to better treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07099417Recruiting
Screening for heart valve disease with a single-lead ECG
This study tests whether a simple single-lead heart monitor (ECG) can spot problems with your heart valves. It may be a quick, easy way to screen for valve disease.
MoscowAges 18 years+ - NCT07112391Recruiting
Pressure volume loop study for valve disease
This trial uses a special heart test called pressure volume loop assessment to better understand how well your heart pumps when you have severe valve disease. It aims to find patterns that may help doctors treat you more effectively. You may join if you have certain types of severe heart valve problems.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07176507Recruiting
Study of multiple and mixed heart valve disease
This study looks at people who have two or more heart valve problems that are moderate to severe. It aims to learn more about this condition and how to best manage it.
LilleAges 18 years+ - NCT07196930Recruiting
Valvular heart disease in women registry
This study is a registry that collects data on women with valvular heart disease (heart valve problems). It aims to better understand how these conditions affect women and improve their care. You may join if you have a heart valve condition and are treated at a participating center.
AswānAges 18 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+ - NCT07367893Recruiting
Exercise echocardiogram registry for heart disease
This study is creating a registry (a database) of patients who have an exercise echocardiogram, which is a stress test that uses ultrasound to look at your heart during exercise. It aims to better understand and diagnose different types of heart disease.
Yongin, Gyeonggi-doAges 18 years+ - NCT03011697Recruiting
Heart valve disease registry for adults
This study enrolls adults in the hospital with certain heart valve problems to track their health over time. It may help doctors better understand how valve disease behaves and what outcomes look like in real life.
Hangzhou, ZhejiangAges 18 years+ - NCT07462260RecruitingPhase 2/Phase 3
Sildenafil for severe pulmonary hypertension from rheumatic valve disease
This trial tests if sildenafil can help people with severe pulmonary hypertension caused by rheumatic valvular heart disease. It aims to see if the drug improves symptoms and heart function.
Hyderābād, SindhAges 18 years+ - NCT07483203Recruiting
Lung blood vessel health in people getting heart valve procedures
This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.
Rochester, MinnesotaAges 18 years+ - NCT07617844Recruiting
Advanced MRI imaging for heart disease diagnosis
This study uses advanced magnetic resonance imaging (MRI) scans to better understand and diagnose heart disease. If you have suspected or confirmed heart problems, this trial may help doctors get clearer pictures of your heart muscle and tissue to figure out what's causing your symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT07456085Enrolling by invitationPhase 3
Rivaroxaban vs warfarin for mechanical heart valves
This trial compares a newer blood thinner (rivaroxaban) to the standard one (warfarin) for people with mechanical heart valves who have had clots or bleeding while on warfarin, or who cannot easily monitor their INR levels. It aims to see if rivaroxaban is safer and more effective.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT07376785Enrolling by invitation
Can smartphones check heart sounds for birth defects?
This study tests whether a smartphone app can accurately detect inborn heart diseases by listening to heart sounds. Participation involves having your heart sounds recorded with a smartphone, which may help find problems earlier.
Hong KongAges 6 years+ - NCT07339007Enrolling by invitation
Validating a heart ultrasound training program for family doctors
This study tests whether a training program helps family doctors use a focused heart ultrasound (FoCUS) to assess patients. If you need a heart ultrasound as part of your regular care, you may be able to join.
Barcelona, CataloniaAges 15 years+ - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT07373119Enrolling by invitation
Frailty reduction in stable heart disease patients
This study tests a program to reduce frailty in older adults with stable coronary artery disease. The goal is to improve strength and well-being in people who are not having recent heart problems.
Barcelona, Select...Ages 70 years+ - NCT07197736Recruiting
Improving heart ultrasound use at Columbia
This study involves cardiologists who read heart ultrasounds in Columbia's echo lab. It aims to improve how these tests are used to help patients.
New York, New YorkAges 18 years+ - NCT07572032RecruitingPhase 4
Heart failure recovery after valve or coronary surgery
This study tests when to start two heart-protective medications (ARNI and SGLT2 inhibitors) after you've had surgery to fix a valve problem or blocked heart arteries. Researchers want to see if waiting a bit before starting these drugs helps your heart recover better.
Daegu, DaeguAges 18 years+ - NCT07192211RecruitingPhase 2
Study of ADR-002K for Heart Failure Patients Having Bypass Surgery
This study tests an experimental drug (ADR-002K) for people with heart failure caused by blocked arteries who are about to have bypass surgery. The goal is to see if it helps the heart recover better after surgery.
Osaka, SuitaAges 18–80 - NCT07057466Recruiting
AI heart check for hidden valve, pressure, or pump problems
This study uses an artificial intelligence (AI) program to read your ECG (a heart tracing) and detect early signs of heart failure, high blood pressure in the lungs, or valve disease before you have symptoms. The goal is to see if AI can catch these problems early.
BristolAges 18–90 - NCT06190834Recruiting
HDL subtypes and heart disease outlook study
This study looks at how different subtypes of HDL (the 'good' cholesterol) relate to the outlook for people with coronary artery disease. If you have heart artery blockages and your HDL subtypes have been checked, this trial might help understand your prognosis better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT07023510Recruiting
VALVE-AI: A study of heart valve health
This trial is testing a new way to check for heart valve problems using your recent ECG (heart electrical test). If you're 60 to 85 and haven't had recent heart imaging or known valve disease, you may qualify.
TaipeiAges 60–85 - NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+
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Common questions
- Are there clinical trials for valvular heart disease?
- Yes. Clin2 currently lists 117 recruiting valvular heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.