Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07393360Recruiting
Muscle preservation during weight loss with GLP-1 drugs
This trial tests a special medical food to help keep muscle mass while losing weight with GLP-1 medications like liraglutide, semaglutide, or tirzepatide. It's for adults with obesity or overweight with related health issues.
MilanAges 18–65 - NCT01927783Recruiting
Community weight loss program for people in Washington area
This study tests a community-based behavioral weight loss program. It may help participants learn practical habits for healthier weight by working with people in local faith communities.
Bethesda, MarylandAges 19–85 - NCT01344525Recruiting
Study of team-based therapy for obesity and weight loss
This study looks at an interdisciplinary, team-based obesity treatment plan and how well it helps people lose significant weight over time. You might be a candidate if you are an adult with obesity who already achieved more than 10% weight loss within about 6 months from a lifestyle program or weight-loss surgery.
HeidelbergAges 18–65 - NCT02829619Recruiting
Eating at Set Times to Help with Weight Loss
This study looks at whether changing when you eat, along with looking at your genes, can help people lose weight. It’s mainly for adults who are above a healthy weight range and don’t have certain health conditions or medicines.
Murcia, MurciaAges 18 years+ - NCT02939664Enrolling by invitation
Laparoscopic gastric bypass vs banding for weight loss
This trial compares two types of minimally invasive weight-loss surgery: gastric bypass versus a gastric band. It looks at which approach works better and is safer for people who qualify for bariatric surgery and have not succeeded with supervised weight-loss programs.
Majadahonda, MadridAges 18–65 - NCT07402031Recruiting
Predicting weight loss from obesity treatments
This study looks at how people lose weight after medication or surgery for obesity. It helps predict which treatment might work best for you.
Brussels, Brussels CapitalAges 18–65 - NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT07433946Recruiting
Liquid nutrition to prevent weight loss in IBD
This study tests whether adding a special liquid nutrition drink (partial enteral nutrition) to your regular diet can help prevent weight loss and muscle loss in people with Crohn's disease or ulcerative colitis who are at risk of malnutrition.
Rozzano, MilanoAges 18–65 - NCT07487090RecruitingPhase 2
Exercise before or after eating
This study compares exercising on an empty stomach versus after eating to see how it affects energy use. It may help you understand when to exercise for better weight management.
Fort Smith, ArkansasAges 18–59 - NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65 - NCT07515547Recruiting
How Obesity Affects the Body Over Time
This research study examines how excess weight impacts your body's health and function, both in the short term and long term. Researchers want to understand the physical changes that happen with obesity and how your body responds.
Montreal, QuebecAges 25–40 - NCT07540754RecruitingPhase 1
How Your Liver Processes a New Injection Medicine
This study tests how your body processes a new medicine called HRS9531 when injected. Researchers want to understand how liver function affects the medicine's breakdown, which helps them determine safe doses for future patients.
Zhengzhou, HenanAges 18–65 - NCT07565051Recruiting
Predicting weight loss after gastric bypass surgery
This study looks at whether measuring muscle mass before gastric bypass surgery can predict how much weight you'll lose afterward. Understanding this connection may help doctors better prepare patients for surgery and set realistic goals.
Geneva, Canton of GenevaAges Any age - NCT07627074Recruiting
Real-world weight loss study with semaglutide
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
Seattle, WashingtonAges 18 years+ - NCT07630597Recruiting
Ear Nerve Stimulation to Help Weight Loss
This trial tests a non-invasive device that gently stimulates a nerve in your ear to help you lose weight after lifestyle changes haven't worked well enough. You wear the device on your ear for 12 weeks while continuing healthy habits.
Nanjing, JiangsuAges 18–50 - NCT07518875Enrolling by invitation
Online weight loss program for Arab adults
This study tests an online dietary weight loss program designed for Arabic-speaking adults. You'll receive 12 educational sessions over 6 months to help manage weight and improve health conditions like diabetes or high blood pressure.
Mecca, Mecca RegionAges 18–75 - NCT07387393Enrolling by invitation
PILI Pasifika Lifestyle Program for Native Hawaiian and Pacific Islander adults
This study tests a 3-month lifestyle program called PILI Pasifika, which includes healthy eating, physical activity, and support for social needs like housing or food. It aims to help Native Hawaiian and Pacific Islander adults with conditions like diabetes or high blood pressure improve their health in real-world settings.
Fayetteville, ArkansasAges 18 years+ - NCT07280221Enrolling by invitation
Wegovy real-world weight loss study in Korea
This study tracks how well Wegovy (a once-weekly injection for weight loss) works for people in Korea who are just starting the medication. It helps doctors understand real-world results outside of a research clinic.
DaejeonAges 19 years+ - NCT07234916Enrolling by invitation
Multivitamins for people starting weight-loss injections
This trial tests whether a multivitamin can help people on the weight-loss injection Tirzepatide maintain healthy vitamin levels. If you're using this injection and meet the other criteria, you may join.
AmersfoortAges 18–70 - NCT06930495Enrolling by invitation
Weight loss and heart failure with normal pumping strength
This study tests whether weight loss treatments can improve muscle and blood vessel function in people with a specific type of heart failure (HFpEF) who also have obesity. It may help if you have heart failure with a normal ejection fraction and a high BMI.
Dallas, TexasAges 18 years+ - NCT06928571Enrolling by invitation
Online tools for weight loss support
This study tests if using online tools can help people lose weight. You will work with your primary care doctor and use a scale and website to track your progress.
Gainesville, FloridaAges 18 years+ - NCT05408728Enrolling by invitation
Check how sugar absorption predicts weight loss after endoscopy
This study looks at whether a person’s “sugar absorption” pattern can help predict how much weight they will lose. It involves an endoscopy (a look inside the upper digestive tract) as part of routine care, and then matching the results to future weight change.
Jacksonville, FloridaAges 18 years+ - NCT04841057Enrolling by invitation
Study of blood and stool changes after weight-loss surgery
This study looks at how your body’s metabolism changes after a specific weight-loss surgery (gastric bypass). It may help researchers better understand what to expect and how to tailor care, while requiring blood draws and stool samples before and after surgery.
Columbia, MissouriAges 18–80 - NCT07351214Enrolling by invitation
Mindfulness support for weight regain after slimming surgery
This trial tests if motivational interviewing combined with mindfulness can help patients manage weight regain after weight loss surgery. You may qualify if you regained weight at least 6 months after surgery.
AnkaraAges Any age
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 194 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.