Clinical trials
Weight Loss clinical trials
Below are recruiting weight loss clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06852391RecruitingPhase 4
Weight loss program with or without semaglutide for teens with obesity
This trial studies how the body adapts to weight loss in teens with obesity. You will either get a behavioral lifestyle program alone or with a weight loss medication called semaglutide.
Hamilton, OntarioAges 12–17 - NCT06862375Recruiting
Mayo Clinic diet for weight loss study
This trial tests if following the Mayo Clinic Diet helps adults with overweight or obesity lose weight. You would use the diet book and app and get support from the study team.
Rochester, MinnesotaAges 18–64 - NCT06911073Recruiting
Postbiotic supplement for weight loss and metabolic health
This trial tests whether a daily postbiotic supplement can help with weight loss and improve metabolic health in adults who are overweight or moderately obese. You would take the supplement while keeping your usual diet and exercise habits.
Birmingham, AlabamaAges 18–65 - NCT06913712Recruiting
BMI and treatment response in IIH
This study looks at how body weight (BMI) affects how well people with Idiopathic Intracranial Hypertension (IIH) respond to treatment. It may help doctors understand if weight influences symptom relief.
Valencia, ValenciaAges 18 years+ - NCT06948825RecruitingPhase 2
Lifestyle program vs. metformin for mothers after gestational diabetes
This study compares a lifestyle program (diet and exercise) with the medication metformin to see which better helps mothers who recently had gestational diabetes improve their health. You may be eligible if you had a single baby, are between 8 weeks and 12 months postpartum, and have a BMI of 25 to 45.
Washington D.C., District of ColumbiaAges 18–45 - NCT06981936RecruitingPhase 4
Do vitamins help prevent deficiencies while on weight-loss injections?
This trial tests if a daily multivitamin and mineral tablet can prevent nutrient shortages in people taking GLP-1 medicines (like Wegovy or Saxenda) for weight loss. You would take either the vitamin tablet or a placebo (a tablet with no active ingredients) for a year, to see which group has better nutrient levels.
AlexandriaAges 18–65 - NCT07059104Recruiting
Breast reconstruction after weight loss surgery study
This study looks at how breast reconstruction with implants works for women who have had major weight loss surgery. It uses national health registries to track outcomes and help doctors and patients make better choices.
GothenburgAges Any age - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65 - NCT07082608Recruiting
Weight loss procedure plus lifestyle changes for sleep apnea
This study tests whether a stomach procedure called endoscopic sleeve gastroplasty (ESG) plus lifestyle changes helps people with sleep apnea lose more weight and improve their breathing compared to lifestyle changes alone. If you have moderate to severe sleep apnea and have struggled to lose weight, this may be an option.
Hyderabad, TelanganaAges 18 years+ - NCT07124832Recruiting
Weight loss study for adults with obesity
This study tests a program to help people with obesity lose weight. It looks at how well the program works and if it is safe for participants.
ManisaAges 18–65 - NCT07144800Recruiting
Family COMIDA: Helping Hispanic families eat healthier
This study aims to help Hispanic/Latino families who are overweight or have obesity eat healthier. It will test a program that includes text messages and video calls to support parents and their children aged 8–12.
New York, New YorkAges 18 years+ - NCT07163650RecruitingPhase 4
Obesity medication 6 months after weight-loss surgery
This trial is for people who had metabolic surgery 6 months ago and still have a BMI of 28 or higher. It tests whether an anti-obesity medication can help with further weight loss after surgery.
Nanjing, JiangsuAges 18–55 - NCT07165431Recruiting
Postbiotic supplement study for overweight and obesity
This study tests whether taking a daily postbiotic gummy for 12 weeks can improve body composition and metabolic health in people with overweight or obesity. It may help if you have stable weight and no major health conditions like diabetes.
Pamplona, NavarreAges 18–70 - NCT07184086RecruitingPhase 1
Weight loss and metabolism study with two medicines
This study tests how two medicines, cagrilintide and semaglutide, affect your metabolism compared to diet alone. It may help you understand how weight loss changes your body's energy use.
Orlando, FloridaAges 18–65 - NCT07213466RecruitingPhase 4
Personalized weight-loss medication for bipolar disorder
This study wants to see if a personalized approach with FDA-approved weight-loss medications can help people with bipolar disorder who are overweight or have obesity, while staying on their mood stabilizer treatment. It might be a good fit if you have bipolar disorder and struggle with your weight.
Rochester, MinnesotaAges 18–65 - NCT07223242RecruitingPhase 2/Phase 3
Tailored exercise training for heart failure with preserved pumping strength
This trial tests a personalized exercise program to help people with a type of heart failure called HFpEF. You may qualify if your heart still pumps well but you have trouble being active, and you are willing to use a phone app and exercise regularly.
Dallas, TexasAges 18 years+ - NCT07223983RecruitingPhase 1
Semaglutide for alcohol use disorder after weight loss surgery
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with alcohol use disorder who have had gastric bypass or sleeve gastrectomy in the past 7 years. It may reduce alcohol cravings or drinking.
New Haven, ConnecticutAges 18 years+ - NCT07237750Recruiting
Weight loss trial: endoscopy procedure vs lifestyle changes
This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.
Beijing, Beijing MunicipalityAges 18–65 - NCT07292441RecruitingPhase 3
Long-term weight loss study for trial participants
This study is for people who finished a previous weight loss trial and want to continue treatment with an injectable medication GZR18. It tests how well the medicine works over a longer period.
Beijing, Beijing MunicipalityAges 18–75 - NCT07297290RecruitingPhase 3
Testing Metformin for Weight Loss in Obesity
This trial tests whether metformin, a common diabetes medicine, can help people with obesity lose weight. It is for people who do not have diabetes and have not used weight loss treatments in the past year.
Enugu, Enugu StateAges 20–59 - NCT07315659Recruiting
Time-restricted eating for weight loss maintenance in obesity
This study tests whether eating only during a set window of hours each day can help people with obesity keep weight off after losing it. You would follow a specific meal schedule and get all your food provided for a period.
Granada, GranadaAges 18–70 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07368777Recruiting
Genetics-based diet counseling vs standard diet for weight loss
This trial compares two types of diet counseling—one based on your genetic makeup and the other standard advice—to see which helps more with weight loss and reducing body fat. It is for adults who are overweight or obese and willing to follow a diet program.
MarousiAges 18–65 - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70
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Common questions
- Are there clinical trials for weight loss?
- Yes. Clin2 currently lists 194 recruiting weight loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weight loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.